Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population. (Q51112214)

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26 March 2020

title

Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27804292 AND SRC:MED&resulttype=core&format=json

26 March 2020

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Qi Yang

1

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26 March 2020

Timothy M Jacobs

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26 March 2020

Justin D McCallen

3

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26 March 2020

Dominic T Moore

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26 March 2020

Justin T Huckaby

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26 March 2020

Jasmine N Edelstein

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26 March 2020

Samuel K Lai

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26 March 2020

language of work or name

English

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publication date

16 November 2016

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26 March 2020

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volume

88

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issue

23

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26 March 2020

page(s)

11804-11812

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Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes

26 March 2020

cites work

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12 December 2020

Accelerated clearance of a second injection of PEGylated liposomes in mice

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12 December 2020

PEGylation, successful approach to drug delivery

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12 December 2020

Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes

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12 December 2020

Antibody against poly(ethylene glycol) adversely affects PEG-asparaginase therapy in acute lymphoblastic leukemia patients

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Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose

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Clinical immunotoxicity of therapeutic proteins

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The aging of the immune system

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Nanoparticle PEGylation for Imaging and Therapy

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12 December 2020

Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials

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Role of the methoxy group in immune responses to mPEG-protein conjugates

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Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy

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12 December 2020

Stratification of antibody-positive subjects by antibody level reveals an impact of immunogenicity on pharmacokinetics

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12 December 2020

Accelerated blood clearance of PEGylated PLGA nanoparticles following repeated injections: effects of polymer dose, PEG coating, and encapsulated anticancer drug.

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12 December 2020

The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage.

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12 December 2020

Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins.

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12 December 2020

Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout

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12 December 2020

Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients

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12 December 2020

Single-dose, subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria: an open-label, multicentre, phase 1 dose-escalation trial

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12 December 2020

IgG subclasses and allotypes: from structure to effector functions

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12 December 2020

Anti-PEG immunity: emergence, characteristics, and unaddressed questions

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12 December 2020

Anti-PEG IgM and complement system are required for the association of second doses of PEGylated liposomes with splenic marginal zone B cells.

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12 December 2020

Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer

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12 December 2020

Immunogenicity of therapeutic recombinant immunotoxins

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12 December 2020

PEGylation of Biopharmaceuticals: A Review of Chemistry and Nonclinical Safety Information of Approved Drugs

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12 December 2020

The Mystery of Antibodies Against Polyethylene Glycol (PEG) - What do we Know?

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12 December 2020

Incidence, characterization, and clinical impact analysis of peginterferon beta1a immunogenicity in patients with multiple sclerosis in the ADVANCE trial

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12 December 2020

Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer

1 reference

12 December 2020

Antibodies against polyethylene glycol produced in animals by immunization with monomethoxy polyethylene glycol modified proteins

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12 December 2020

Polyethylene glycol reactive antibodies in man: titer distribution in allergic patients treated with monomethoxy polyethylene glycol modified allergens or placebo, and in healthy blood donors

1 reference

12 December 2020

Heterogeneity in surface antigen and glycoprotein expression of cell lines derived from different melanoma metastases of the same patient. Implications for the study of tumor antigens

1 reference

12 December 2020

Grafted poly-(ethylene glycol) on lipid surfaces inhibits protein adsorption and cell adhesion

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12 December 2020

A single dose of intravenously injected poloxamine-coated long-circulating particles triggers macrophage clearance of subsequent doses in rats.

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12 December 2020

A statistically defined endpoint titer determination method for immunoassays

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12 December 2020

10.1021/ACS.ANALCHEM.6B03437

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27804292 AND SRC:MED&resulttype=core&format=json

26 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27804292 AND SRC:MED&resulttype=core&format=json

26 March 2020

PubMed publication ID

27804292

1 reference