Curcumin acts via transient receptor potential vanilloid-1 receptors to inhibit gut nociception and reverses visceral hyperalgesia. (Q51023920)

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29 February 2020

title

Curcumin acts via transient receptor potential vanilloid-1 receptors to inhibit gut nociception and reverses visceral hyperalgesia (English)

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sensory perception of pain

29 February 2020

main subject

curcumin

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6

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29 February 2020

author name string

L Zhi

1

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29 February 2020

L Dong

2

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29 February 2020

D Kong

3

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B Sun

4

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Q Sun

5

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G Zhang

7

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W Rong

8

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publication date

3 May 2013

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Neurogastroenterology and Motility

29 February 2020

published in

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volume

25

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issue

6

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page(s)

e429-40

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Sensory signal transduction in the vagal primary afferent neurons.

29 February 2020

cites work

1 reference

Vanilloid receptor type 1-immunoreactivity is expressed by intrinsic afferent neurones in the guinea-pig myenteric plexus.

21 January 2018

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Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.

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The cloned capsaicin receptor integrates multiple pain-producing stimuli

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The vanilloid receptor: a molecular gateway to the pain pathway

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A capsaicin-receptor homologue with a high threshold for noxious heat

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Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1.

21 January 2018

1 reference

The mechanosensitivity of mouse colon afferent fibers and their sensitization by inflammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3.

21 January 2018

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Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice

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TRPV1 receptor signaling mediates afferent nerve sensitization during colitis-induced motility disorders in rats.

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Inhibition of the vanilloid receptor subtype-1 attenuates TNBS-colitis

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Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats

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1 reference

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1 reference

Stimulation of dichlorofluorescin oxidation by capsaicin and analogues in RAW 264 monocyte/macrophages: lack of involvement of the vanilloid receptor

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Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.

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Through metal binding, curcumin protects against lead- and cadmium-induced lipid peroxidation in rat brain homogenates and against lead-induced tissue damage in rat brain.

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Inhibition of human low density lipoprotein oxidation by active principles from spices

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Protective activities of some phenolic 1,3-diketones against lipid peroxidation: possible involvement of the 1,3-diketone moiety

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Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication

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Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain

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Evaluation of antihyperalgesic effect of curcumin on formalin-induced orofacial pain in rat.

21 January 2018

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The effect of curcumin (active substance of turmeric) on the acetic acid-induced visceral nociception in rats

21 January 2018

1 reference

Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation

21 January 2018

1 reference

Curcumin's effect on intestinal inflammation and tumorigenesis in the ApcMin/ mouse

21 January 2018

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Curcumin attenuates DNB-induced murine colitis.

21 January 2018

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Curcumin prevents and ameliorates trinitrobenzene sulfonic acid-induced colitis in mice

21 January 2018

1 reference

Curcumin, the major component of food flavour turmeric, reduces mucosal injury in trinitrobenzene sulphonic acid-induced colitis

21 January 2018

1 reference

A potential role for the vanilloid receptor TRPV1 in the therapeutic effect of curcumin in dinitrobenzene sulphonic acid-induced colitis in mice

21 January 2018

1 reference

Curcumin produces an antihyperalgesic effect via antagonism of TRPV1.

21 January 2018

1 reference

Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system

21 January 2018

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Inhibition of the SERCA Ca2 pumps by curcumin. Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP.

21 January 2018

1 reference

Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells.

21 January 2018

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Curcumin: a new cell-permeant inhibitor of the inositol 1,4,5-trisphosphate receptor.

21 January 2018

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Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells

21 January 2018

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Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells.

21 January 2018

1 reference

Curcumin exerts antinociceptive effects in a mouse model of neuropathic pain: Descending monoamine system and opioid receptors are differentially involved

21 January 2018

1 reference

Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans

21 January 2018

1 reference

The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/NMO.12145

1 reference

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29 February 2020

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