High frequency of IKZF1 genetic alterations in adult patients with B-cell acute lymphoblastic leukemia (Q50921558)

25 March 2018

title

High frequency of IKZF1 genetic alterations in adult patients with B-cell acute lymphoblastic leukemia (English)

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Kenji Tokunaga

1

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Shunichiro Yamaguchi

2

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Eisaku Iwanaga

3

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Tomoko Nanri

4

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Taizo Shimomura

5

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Hitoshi Suzushima

6

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Hiroaki Mitsuya

7

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Norio Asou

8

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publication date

7 July 2013

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European Journal of Haematology

published in

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volume

91

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issue

3

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page(s)

201-208

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The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia

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A pathway-based gene signature correlates with therapeutic response in adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

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TEL/AML1 fusion gene resulting from a cryptic t(12;21) is uncommon in adult patients with B-cell lineage ALL and CML lymphoblastic transformation

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Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

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Haematopoietic cell-fate decisions, chromatin regulation and ikaros

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Intensified consolidation therapy with dose-escalated doxorubicin did not improve the prognosis of adults with acute lymphoblastic leukemia: the JALSG-ALL97 study

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Combination of intensive chemotherapy and imatinib can rapidly induce high-quality complete remission for a majority of patients with newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia

21 January 2018

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Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute

21 January 2018

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Expression of dominant-negative Ikaros isoforms and associated genetic alterations in Chinese adult patients with leukemia

21 January 2018

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Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

21 January 2018

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

21 January 2018

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IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia

21 January 2018

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Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.

21 January 2018

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Frequent pathway mutations of splicing machinery in myelodysplasia

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Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study.

21 January 2018

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Chemotherapy-phased imatinib pulses improve long-term outcome of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: Northern Italy Leukemia Group protocol 09/00.

21 January 2018

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Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance

21 January 2018

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IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report

21 January 2018

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Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia.

21 January 2018

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BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

21 January 2018

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Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph ALL)

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Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia

21 January 2018

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Identifiers

DOI

10.1111/EJH.12155

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25 March 2018

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25 March 2018