Moderately high intake of folic acid has a negative impact on mouse embryonic development (Q50777137)

19 March 2018

title

Moderately high intake of folic acid has a negative impact on mouse embryonic development (English)

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5

Rima Rozen

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Jacob Selhub

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object named as

Jacob Selhub

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19 March 2018

author name string

Leonie G Mikael

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Liyuan Deng

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Ligi Paul

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publication date

2 November 2012

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Birth Defects Research Part A: Clinical and Molecular Teratology

published in

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volume

97

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issue

1

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page(s)

47-52

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The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake

cites work

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Folic acid to reduce neonatal mortality from neural tube disorders

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Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice

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Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation

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Nutritional interpretation of folic acid interventions

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Postnatal closure of membranous ventricular septal defects in Sprague-Dawley rat pups after maternal exposure with trimethadione

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Pre- and postfortification intake of folate and risk of colorectal cancer in a large prospective cohort study in the United States

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Perspectives on obesity and sweeteners, folic acid fortification and vitamin D requirements

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Folate rescues lithium-, homocysteine- and Wnt3A-induced vertebrate cardiac anomalies

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Long-term effect of low-dose folic acid intake: potential effect of mandatory fortification on the prevention of neural tube defects

21 January 2018

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Folate status of reproductive age women and neural tube defect risk: the effect of long-term folic acid supplementation at doses of 140 µg and 400 µg per day.

21 January 2018

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Model systems for the study of heart development and disease. Cardiac neural crest and conotruncal malformations

21 January 2018

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Infant methylenetetrahydrofolate reductase 677TT genotype is a risk factor for congenital heart disease

21 January 2018

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Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/ mice.

21 January 2018

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Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival.

21 January 2018

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A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis

21 January 2018

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Estimation of trends in serum and RBC folate in the U.S. population from pre- to postfortification using assay-adjusted data from the NHANES 1988-2010

21 January 2018

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High intake of folic acid disrupts embryonic development in mice

21 January 2018

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Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice

21 January 2018

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Safety considerations and potential interactions of vitamins: should vitamins be considered drugs?

21 January 2018

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High levels of folate from supplements and fortification are not associated with increased risk of colorectal cancer

21 January 2018

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Protective effect of periconceptional folic acid supplements on the risk of congenital heart defects: a registry-based case-control study in the northern Netherlands

21 January 2018

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Cardiac Neural Crest Cells Provide New Insight into Septation of the Cardiac Outflow Tract: Aortic Sac to Ventricular Septal Closure

21 January 2018

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Association of the C677T methylenetetrahydrofolate reductase mutation and elevated homocysteine levels with congenital cardiac malformations

21 January 2018

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Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study.

21 January 2018

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Maternal and offspring MTHFR gene C677T polymorphism as predictors of congenital atrial septal defect and patent ductus arteriosus

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Identifiers

DOI

10.1002/BDRA.23092

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19 March 2018

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19 March 2018