Sphingosin-1-phosphate Receptor 1: a Potential Target to Inhibit Neuroinflammation and Restore the Sphingosin-1-phosphate Metabolism (Q50592328)

16 March 2018

title

Sphingosin-1-phosphate Receptor 1: a Potential Target to Inhibit Neuroinflammation and Restore the Sphingosin-1-phosphate Metabolism (English)

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author name string

Zeynab Kolahdooz

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Sanaz Nasoohi

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Masoumeh Asle-Rousta

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Abolhassan Ahmadiani

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publication date

10 April 2015

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Canadian Journal of Neurological Sciences

published in

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volume

42

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issue

3

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page(s)

195-202

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Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development of Alzheimer's disease

cites work

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ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimer's but not normal brain

21 January 2018

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Perturbation of sphingolipid metabolism and ceramide production in HIV-dementia

21 January 2018

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FTY720/fingolimod, a sphingosine analogue, reduces amyloid-β production in neurons.

21 January 2018

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Effects of small interfering RNA targeting sphingosine kinase-1 gene on the animal model of Alzheimer's disease

21 January 2018

1 reference

Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis

21 January 2018

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Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus.

21 January 2018

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Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension

21 January 2018

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Sphingosine 1-phosphate and cancer

21 January 2018

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Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E.

21 January 2018

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Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function

21 January 2018

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Amyloid-beta peptide enhances tumor necrosis factor-alpha-induced iNOS through neutral sphingomyelinase/ceramide pathway in oligodendrocytes

21 January 2018

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Sphingosine-1-phosphate phosphatases

21 January 2018

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Sphingosine-1-phosphate signaling and its role in disease

21 January 2018

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S1P metabolism in cancer and other pathological conditions

21 January 2018

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Aberrant upregulation of astroglial ceramide potentiates oligodendrocyte injury.

21 January 2018

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

21 January 2018

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Fingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid β-induced memory impairment.

21 January 2018

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Biologically active sphingolipids in cancer pathogenesis and treatment

21 January 2018

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Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?

21 January 2018

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Essential role for sphingosine kinases in neural and vascular development

21 January 2018

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Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

21 January 2018

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Inhibitors of the sphingosine kinase pathway as potential therapeutics.

21 January 2018

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Deregulation of sphingolipid metabolism in Alzheimer's disease

21 January 2018

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Distribution of sphingosine kinase activity and mRNA in rodent brain

21 January 2018

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A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging

21 January 2018

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Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

21 January 2018

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Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility

21 January 2018

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Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720

21 January 2018

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Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons

21 January 2018

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Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

21 January 2018

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Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance

21 January 2018

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Morris water maze: procedures for assessing spatial and related forms of learning and memory

21 January 2018

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Dual effects of daily FTY720 on human astrocytes in vitro: relevance for neuroinflammation

21 January 2018

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S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate

21 January 2018

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FTY720 (fingolimod) attenuates beta-amyloid peptide (Aβ42)-induced impairment of spatial learning and memory in rats

21 January 2018

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Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

21 January 2018

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Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate

21 January 2018

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Sphingosine kinase 1 deficiency exacerbates LPS-induced neuroinflammation

21 January 2018

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FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

21 January 2018

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Sphingosine Kinase 1 Mediation of Expression of the Anaphylatoxin Receptor C5L2 Dampens the Inflammatory Response to Endotoxin

21 January 2018

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Sphingosine kinase protects lipopolysaccharide-activated macrophages from apoptosis

21 January 2018

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Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier

21 January 2018

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Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia.

21 January 2018

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Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages

21 January 2018

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Sphingosine Kinase 1 and Sphingosine 1-Phosphate Receptor 3 Are Functionally Upregulated on Astrocytes under Pro-Inflammatory Conditions

21 January 2018

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Heterogeneity of microglial activation in the innate immune response in the brain

21 January 2018

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Vascular biology: the role of sphingosine 1-phosphate in both the resting state and inflammation

21 January 2018

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Brain membrane phospholipid alterations in Alzheimer's disease

21 January 2018

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BACE1 activity is modulated by cell-associated sphingosine-1-phosphate.

21 January 2018

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Sphingosine-1-phosphate: an enigmatic signalling lipid

21 January 2018

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Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease

21 January 2018

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7 January 2021

The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity

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7 January 2021

Fingolimod protects cultured cortical neurons against excitotoxic death

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7 January 2021

The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor

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7 January 2021

Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy

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7 January 2021

Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis.

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7 January 2021

Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization-liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal

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7 January 2021

Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway

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7 January 2021

Identifiers

DOI

10.1017/CJN.2015.19

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16 March 2018

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16 March 2018