Cell division cycle 7 (Q5058187)

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mammalian protein found in Homo sapiens

CDC7-related kinase
cell division cycle 7 homolog
epididymis secretory sperm binding protein
CDC7
cell division cycle 7-related protein kinase
cell division cycle 7-like protein 1
CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1

Language	Label	Description	Also known as
English	Cell division cycle 7	mammalian protein found in Homo sapiens	CDC7-related kinase cell division cycle 7 homolog epididymis secretory sperm binding protein CDC7 cell division cycle 7-related protein kinase cell division cycle 7-like protein 1 CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1

Statements

1 reference

13 November 2019

UniProt protein ID

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00311

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

protein kinase activity

determination method or standard

3 references

8 April 2019

A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

8 April 2019

Drf1, a novel regulatory subunit for human Cdc7 kinase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

nucleotide binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

metal ion binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

protein binding

determination method or standard

6 references

8 April 2019

A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

8 April 2019

Drf1, a novel regulatory subunit for human Cdc7 kinase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

8 April 2019

Interaction of human minichromosome maintenance protein-binding protein with minichromosome maintenance 2-7

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

8 April 2019

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

8 April 2019

Crystal structure of human CDC7 kinase in complex with its activator DBF4

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

8 April 2019

Interactions of the human MCM-BP protein with MCM complex components and Dbf4

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

protein serine/threonine kinase activity

determination method or standard

1 reference

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00311&geneProductId=UniProtKB:O00311

determination method or standard

determination method or standard

1 reference

10 September 2018

Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00311&geneProductId=UniProtKB:O00311

determination method or standard

intercellular bridge

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

mitotic spindle

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

8 April 2019

Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

determination method or standard

biological process

cell cycle phase transition

determination method or standard

1 reference

8 April 2019

Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

phosphorylation

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

double-strand break repair via break-induced replication

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

positive regulation of nuclear cell cycle DNA replication

determination method or standard

1 reference

8 April 2019

A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

DNA replication

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

protein phosphorylation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

DNA replication initiation

determination method or standard

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00311&geneProductId=UniProtKB:O00311

determination method or standard

peptidyl-serine phosphorylation

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

positive regulation of cell population proliferation

determination method or standard

1 reference

8 April 2019

Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

determination method or standard

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00311&geneProductId=UniProtKB:O00311

determination method or standard

positive regulation of G2/M transition of mitotic cell cycle

determination method or standard

1 reference

8 April 2019

A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

regulation of cell shape

determination method or standard

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00311&geneProductId=UniProtKB:O00311

determination method or standard

negative regulation of G0 to G1 transition

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

peptidyl-threonine phosphorylation

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00311

determination method or standard

Gene Atlas image

PBB GE CDC7 204510 at fs.png
732 × 530; 11 KB

0 references

http://purl.uniprot.org/uniprot/O00311

1 reference

Identifiers.org

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00311

protein kinase, ATP binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00311

serine/threonine-protein kinase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00311

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000234626

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000234626

ENSP00000393139

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000393139

ENSP00000398077

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000398077

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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