A novel upstream enhancer of FOXP3, sensitive to methylation-induced silencing, exhibits dysregulated methylation in rheumatoid arthritis Treg cells. (Q50452727)

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scientific article published on 18 August 2014

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English	A novel upstream enhancer of FOXP3, sensitive to methylation-induced silencing, exhibits dysregulated methylation in rheumatoid arthritis Treg cells.	scientific article published on 18 August 2014

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10 March 2020

A novel upstream enhancer of FOXP3, sensitive to methylation-induced silencing, exhibits dysregulated methylation in rheumatoid arthritis Treg cells (English)

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10 March 2020

rheumatoid arthritis

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10 March 2020

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10 March 2020

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Emily M Schmidt

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10 March 2020

Henry Penn

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10 March 2020

Parisa Amjadi

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10 March 2020

Khaja Syed

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10 March 2020

Jordan E Read

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10 March 2020

Patricia Green

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10 March 2020

Bernard Gregory

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10 March 2020

Fionula M Brennan

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10 March 2020

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18 August 2014

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10 March 2020

European Journal of Immunology

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10 March 2020

44

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10 March 2020

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10 March 2020

2968-2978

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10 March 2020

Relative importance of genetic effects in rheumatoid arthritis: historical cohort study of Danish nationwide twin population.

1 reference

https://api.crossref.org/works/10.1002/EJI.201444453

21 January 2018

Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis.

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21 January 2018

DNA methylome signature in rheumatoid arthritis

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An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype

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Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

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21 January 2018

Naturally arising Foxp3-expressing CD25 CD4 regulatory T cells in immunological tolerance to self and non-self

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21 January 2018

Immunologic tolerance maintained by CD25 CD4 regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

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Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

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21 January 2018

Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis

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21 January 2018

Resistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells

1 reference

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21 January 2018

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

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21 January 2018

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

1 reference

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21 January 2018

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3( ) conventional T cells.

1 reference

https://api.crossref.org/works/10.1002/EJI.201444453

21 January 2018

DNA methylation controls Foxp3 gene expression

1 reference

https://api.crossref.org/works/10.1002/EJI.201444453

21 January 2018

FOXP3 promoter demethylation reveals the committed Treg population in humans.

1 reference

https://api.crossref.org/works/10.1002/EJI.201444453

21 January 2018

Molecular mechanisms underlying FOXP3 induction in human T cells

1 reference

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21 January 2018

Development of Foxp3( ) regulatory t cells is driven by the c-Rel enhanceosome

1 reference

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21 January 2018

Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation

1 reference

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21 January 2018

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

1 reference

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21 January 2018

Epigenetic alterations in autoimmune rheumatic diseases

1 reference

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Demethylation analysis of the FOXP3 locus shows quantitative defects of regulatory T cells in IPEX-like syndrome.

1 reference

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21 January 2018

Quantification of regulatory T cells in septic patients by real-time PCR-based methylation assay and flow cytometry

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21 January 2018

Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue

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21 January 2018

CD2 costimulation reveals defective activity by human CD4 CD25(hi) regulatory cells in patients with multiple sclerosis

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21 January 2018

Demethylation of the FOXP3 gene in human melanoma cells precludes the use of this epigenetic mark for quantification of Tregs in unseparated melanoma samples.

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21 January 2018

FOXP3 regulatory T cells in the human immune system

1 reference

https://api.crossref.org/works/10.1002/EJI.201444453

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DNA hypomethylation in inflammatory arthritis: reversal with methotrexate

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Prevalence of ZAP-70, LAT, SLP-76, and DNA methyltransferase 1 expression in CD4 T cells of patients with systemic lupus erythematosus.

1 reference

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21 January 2018

Abnormal DNA methylation in CD4 T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis

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21 January 2018

Regulation of DNA methylation in rheumatoid arthritis synoviocytes

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Meta-analysis: diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthritis

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21 January 2018

Rheumatoid factor determines structural progression of rheumatoid arthritis dependent and independent of disease activity

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21 January 2018

Rheumatoid factor is the strongest predictor of radiological progression of rheumatoid arthritis in a three-year prospective study in community-recruited patients

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CD4 CD25 T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis

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CD4( )CD25( ) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid

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Commentary: Do genes or environment influence development of rheumatoid arthritis?

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7 January 2021

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Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis

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Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts

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T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development

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Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis

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7 January 2021

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