G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning (Q50336980)

5 March 2018

title

G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning (English)

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G protein-coupled receptor

main subject

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2

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author name string

Sun-Hee Hwang

series ordinal

1

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5 March 2018

publication date

11 June 2014

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Birth Defects Research Part A: Clinical and Molecular Teratology

published in

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volume

103

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issue

1

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page(s)

12-19

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Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube

cites work

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Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

21 January 2018

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Sonic-hedgehog-mediated proliferation requires the localization of PKA to the cilium base.

21 January 2018

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Subunit Interactions and Organization of the Chlamydomonas reinhardtii Intraflagellar Transport Complex A Proteins

21 January 2018

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Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors

21 January 2018

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Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia

21 January 2018

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Intraflagellar transport complex structure and cargo interactions

21 January 2018

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The graded response to Sonic Hedgehog depends on cilia architecture

21 January 2018

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Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning

21 January 2018

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Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

21 January 2018

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

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Vertebrate Smoothened functions at the primary cilium

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Direct recording and molecular identification of the calcium channel of primary cilia.

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Primary cilia are specialized calcium signalling organelles

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Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism

21 January 2018

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A Smoothened-Evc2 complex transduces the Hedgehog signal at primary cilia

21 January 2018

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Analysis of mouse embryonic patterning and morphogenesis by forward genetics

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Selective targeting of somatostatin receptor 3 to neuronal cilia

21 January 2018

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Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

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21 January 2018

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Cilia and Hedgehog responsiveness in the mouse

21 January 2018

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Hedgehog signalling in the mouse requires intraflagellar transport proteins

21 January 2018

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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

21 January 2018

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Proteomic Analysis of Mammalian Primary Cilia

21 January 2018

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Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia

21 January 2018

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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

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The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia

21 January 2018

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IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport

21 January 2018

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Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

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Regulating the transition from centriole to basal body

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A motility in the eukaryotic flagellum unrelated to flagellar beating

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The orphan G protein-coupled receptor 161 is required for left-right patterning

21 January 2018

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The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking

21 January 2018

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Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

21 January 2018

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Neuropeptide Y family receptors traffic via the Bardet-Biedl syndrome pathway to signal in neuronal primary cilia

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DISC1 regulates primary cilia that display specific dopamine receptors

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The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development

21 January 2018

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The tubby family proteins

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TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia

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The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling

21 January 2018

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A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

21 January 2018

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Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.

21 January 2018

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Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling

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Complex interactions between genes controlling trafficking in primary cilia

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A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome

21 January 2018

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Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway

21 January 2018

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EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia

21 January 2018

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Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

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Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification

21 January 2018

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Patched1 regulates hedgehog signaling at the primary cilium

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Intraflagellar transport

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Intraflagellar transport motors in cilia: moving along the cell's antenna

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A three-part signal governs differential processing of Gli1 and Gli3 proteins by the proteasome

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The primary cilium as the cell's antenna: signaling at a sensory organelle

21 January 2018

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Targeting of vasoactive intestinal peptide receptor 2, VPAC2, a secretin family G-protein coupled receptor, to primary cilia

21 January 2018

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Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

21 January 2018

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Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP.

21 January 2018

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THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia

21 January 2018

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A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes

21 January 2018

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Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube

21 January 2018

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Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

21 January 2018

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Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors

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Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

21 January 2018

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Specified neural progenitors sort to form sharp domains after noisy Shh signaling.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BDRA.23267

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5 March 2018

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5 March 2018