Glycemic Effect and Safety of a Systemic, Partial Glucokinase Activator, PF-04937319, in Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin-A Randomized, Crossover, Active-Controlled Study. (Q50223164)

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scientific article published on 6 May 2016

Language	Label	Description	Also known as
English	Glycemic Effect and Safety of a Systemic, Partial Glucokinase Activator, PF-04937319, in Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin-A Randomized, Crossover, Active-Controlled Study.	scientific article published on 6 May 2016

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27870481 AND SRC:MED&resulttype=core&format=json

27 March 2020

Glycemic Effect and Safety of a Systemic, Partial Glucokinase Activator, PF-04937319, in Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin-A Randomized, Crossover, Active-Controlled Study (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27870481 AND SRC:MED&resulttype=core&format=json

27 March 2020

1 reference

based on heuristic

inferred from title

type 2 diabetes

1 reference

based on heuristic

inferred from title

William S Denney

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27870481 AND SRC:MED&resulttype=core&format=json

27 March 2020

author name string

Douglas S Denham

2

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Europe PubMed Central

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27 March 2020

Michael R Riggs

3

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Europe PubMed Central

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27 March 2020

Neeta B Amin

4

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27 March 2020

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6 May 2016

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27 March 2020

Clinical pharmacology in drug development

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Europe PubMed Central

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27 March 2020

5

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27 March 2020

6

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27 March 2020

517-527

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27 March 2020

Novel treatments for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

GKAs for diabetes therapy: why no clinically useful drug after two decades of trying?

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Effects of MK-0941, a Novel Glucokinase Activator, on Glycemic Control in Insulin-Treated Patients With Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Dose-ranging study with the glucokinase activator AZD1656 in patients with type 2 diabetes mellitus on metformin

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

The relationship of glucokinase activator-induced hypoglycemia with arteriopathy, neuronal necrosis, and peripheral neuropathy in nonclinical studies

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Two dose-ranging studies with PF-04937319, a systemic partial activator of glucokinase, as add-on therapy to metformin in adults with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Sitagliptin 100 mg daily effect on DPP-4 inhibition and compound-specific glycemic improvement

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Diagnosis and Classification of Diabetes Mellitus

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Prediction of creatinine clearance from serum creatinine

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Metabolites in safety testing assessment in early clinical development: a case study with a glucokinase activator.

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

A model-based approach to predict longitudinal HbA1c, using early phase glucose data from type 2 diabetes mellitus patients after anti-diabetic treatment.

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Effects of JNJ-38431055, a novel GPR119 receptor agonist, in randomized, double-blind, placebo-controlled studies in subjects with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Effects of once-daily sitagliptin on 24-h glucose control following 4 weeks of treatment in Japanese patients with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Saxagliptin and metformin XR combination therapy provides glycemic control over 24 hours in patients with T2DM inadequately controlled with metformin

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Efficacy and tolerability of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy over 12 weeks in patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Once-daily sitagliptin, a dipeptidyl peptidase-4 inhibitor, for the treatment of patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Comparison of vildagliptin twice daily vs. sitagliptin once daily using continuous glucose monitoring (CGM): crossover pilot study (J-VICTORIA study).

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Effect of sitagliptin on glucose control in adult patients with Type 1 diabetes: a pilot, double-blind, randomized, crossover trial

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Effect of adding sitagliptin, a dipeptidyl peptidase-4 inhibitor, to metformin on 24-h glycaemic control and beta-cell function in patients with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

An efficient analysis of covariance model for crossover thorough QT studies with period-specific baseline days

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Translating the A1C assay into estimated average glucose values

1 reference

https://api.crossref.org/works/10.1002/CPDD.261

21 January 2018

Cross-over trials in Statistics in Medicine: the first '25' years

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7 January 2021

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10.1002/CPDD.261

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27870481 AND SRC:MED&resulttype=core&format=json

27 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27870481 AND SRC:MED&resulttype=core&format=json

27 March 2020

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