Posttranslational Modification of Sodium Channels (Q50086104)

24 February 2018

title

Posttranslational Modification of Sodium Channels (English)

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24 February 2018

author name string

Zifan Pei

series ordinal

1

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24 February 2018

Yanling Pan

series ordinal

2

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24 February 2018

Theodore R Cummins

series ordinal

3

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24 February 2018

publication date

26 October 2017

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24 February 2018

Handbook of experimental pharmacology

published in

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24 February 2018

Regulation of the cardiac voltage-gated Na channel (H1) by the ubiquitin-protein ligase Nedd4.

cites work

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Na channel regulation by Ca2 /calmodulin and Ca2 /calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes

21 January 2018

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Palmitoylation of nicotinic acetylcholine receptors

21 January 2018

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Ca2 /calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites

21 January 2018

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Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures

21 January 2018

1 reference

A novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic response

21 January 2018

1 reference

Protein arginine methyl transferases-3 and -5 increase cell surface expression of cardiac sodium channel

21 January 2018

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Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel.

21 January 2018

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Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

21 January 2018

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Serine-1321-independent regulation of the mu 1 adult skeletal muscle Na channel by protein kinase C

21 January 2018

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Contribution of sialic acid to the voltage dependence of sodium channel gating. A possible electrostatic mechanism

21 January 2018

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Multisite phosphorylation of voltage-gated sodium channel alpha subunits from rat brain

21 January 2018

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Palmitoylation influences the function and pharmacology of sodium channels.

21 January 2018

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Detection of protein palmitoylation in cultured hippocampal neurons by immunoprecipitation and acyl-biotin exchange (ABE).

21 January 2018

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C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation.

21 January 2018

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Neuronal expression of the ubiquitin ligase Nedd4-2 in rat dorsal root ganglia: modulation in the spared nerve injury model of neuropathic pain.

21 January 2018

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International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

21 January 2018

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Specific modulation of Na channels in hippocampal neurons by protein kinase C epsilon.

21 January 2018

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Identification of the cysteine residue responsible for disulfide linkage of Na channel α and β2 subunits

21 January 2018

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Caveolin-3 suppresses late sodium current by inhibiting nNOS-dependent S-nitrosylation of SCN5A.

21 January 2018

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Phosphorylation of the alpha subunit of the sodium channel by protein kinase C.

21 January 2018

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Human neocortical excitability is decreased during anoxia via sodium channel modulation

21 January 2018

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The role of palmitoylation in functional expression of nicotinic alpha7 receptors.

21 January 2018

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Hierarchical CRMP2 posttranslational modifications control NaV1.7 function

21 January 2018

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Expression of the sialyltransferase, ST3Gal4, impacts cardiac voltage-gated sodium channel activity, refractory period and ventricular conduction

21 January 2018

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Sialic acids attached to N- and O-glycans within the Nav1.4 D1S5-S6 linker contribute to channel gating

21 January 2018

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Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

21 January 2018

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Identification of PSD-95 palmitoylating enzymes

21 January 2018

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Two Nedd4-binding motifs underlie modulation of sodium channel Nav1.6 by p38 MAPK.

21 January 2018

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Resurgence of sodium channel research

21 January 2018

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Mechanisms of sodium channel inactivation

21 January 2018

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The human Kv1.1 channel is palmitoylated, modulating voltage sensing: Identification of a palmitoylation consensus sequence

21 January 2018

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Activation of protein kinase C alters the intracellular distribution and mobility of cardiac Na channels

21 January 2018

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

21 January 2018

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Nitric oxide increases persistent sodium current in rat hippocampal neurons

21 January 2018

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Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.

21 January 2018

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CaMKII Phosphorylation of Na(V)1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure

21 January 2018

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Identification and expression of delta-isoforms of the multifunctional Ca2 /calmodulin-dependent protein kinase in failing and nonfailing human myocardium

21 January 2018

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A quantitative description of membrane current and its application to conduction and excitation in nerve

21 January 2018

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The sialic acid component of the beta1 subunit modulates voltage-gated sodium channel function

21 January 2018

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Oxidation of multiple methionine residues impairs rapid sodium channel inactivation

21 January 2018

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Human DHHC proteins: a spotlight on the hidden player of palmitoylation

21 January 2018

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Ca2 /calmodulin-dependent protein kinase II-based regulation of voltage-gated Na channel in cardiac disease.

21 January 2018

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β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells

21 January 2018

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Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain.

21 January 2018

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Ubiquitylation of voltage-gated sodium channels.

21 January 2018

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Voltage-gated sodium channel expression in mouse DRG after SNI leads to re-evaluation of projections of injured fibers

21 January 2018

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Suppression of phosphoinositide 3-kinase signaling and alteration of multiple ion currents in drug-induced long QT syndrome

21 January 2018

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Increased persistent sodium current due to decreased PI3K signaling contributes to QT prolongation in the diabetic heart

21 January 2018

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Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes

21 January 2018

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Modulation of late sodium current by Ca2 , calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences

21 January 2018

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Regulation of the cardiac Na channel NaV1.5 by post-translational modifications.

21 January 2018

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Mass spectrometry-based identification of native cardiac Nav1.5 channel α subunit phosphorylation sites.

21 January 2018

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Large-scale profiling of protein palmitoylation in mammalian cells

21 January 2018

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Nav1.5 channels can reach the plasma membrane through distinct N-glycosylation states

21 January 2018

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Modulation of an inactivating human cardiac K channel by protein kinase C.

21 January 2018

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Functional effects of protein kinase C activation on the human cardiac Na channel

21 January 2018

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Functional modulation of brain sodium channels by protein kinase C phosphorylation

21 January 2018

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Oxygen deprivation inhibits Na current in rat hippocampal neurones via protein kinase C

21 January 2018

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The crystal structure of a voltage-gated sodium channel

21 January 2018

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Cardiac sodium channel palmitoylation regulates channel availability and myocyte excitability with implications for arrhythmia generation

21 January 2018

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SUMOylation of NaV1.2 channels mediates the early response to acute hypoxia in central neurons.

21 January 2018

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Phosphorylation of S1505 in the cardiac Na channel inactivation gate is required for modulation by protein kinase C.

21 January 2018

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Nitric oxide blocks fast, slow, and persistent Na channels in C-type DRG neurons by S-nitrosylation

21 January 2018

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Defective fast inactivation recovery and deactivation account for sodium channel myotonia in the I1160V mutant

21 January 2018

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Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins

21 January 2018

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Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx (5cv) mice.

21 January 2018

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Oxidation differentially modulates the recombinant voltage-gated Na( ) channel α-subunits Nav1.7 and Nav1.8.

21 January 2018

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Biosynthesis and processing of the alpha subunit of the voltage-sensitive sodium channel in rat brain neurons

21 January 2018

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Conventional protein kinase C isoforms and cross-activation of protein kinase A regulate cardiac Na current

21 January 2018

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Ion channel regulation by protein palmitoylation.

21 January 2018

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Ion channel regulation by protein S-acylation

21 January 2018

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Slow inactivation of Na( ) channels.

21 January 2018

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Redox signaling: nitrosylation and related target interactions of nitric oxide

21 January 2018

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(S)NO signals: translocation, regulation, and a consensus motif

21 January 2018

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Formation of aquaporin-4 arrays is inhibited by palmitoylation of N-terminal cysteine residues.

21 January 2018

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Protein kinase C enhances human sodium channel hNav1.7 resurgent currents via a serine residue in the domain III-IV linker

21 January 2018

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Dysregulation of sodium channel gating in critical illness myopathy

21 January 2018

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Palmitoylation by DHHC5/8 targets GRIP1 to dendritic endosomes to regulate AMPA-R trafficking

21 January 2018

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Sodium channel inactivation: molecular determinants and modulation

21 January 2018

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Modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by protein kinase A and protein kinase C.

21 January 2018

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Slow inactivation in voltage-gated sodium channels: molecular substrates and contributions to channelopathies

21 January 2018

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Role of sodium and calcium dysregulation in tachyarrhythmias in sudden cardiac death

21 January 2018

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Sodium channel alpha1-subunit mutations in severe myoclonic epilepsy of infancy and infantile spasms.

21 January 2018

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Removal of sodium channel inactivation in squid axon by the oxidant chloramine-T.

21 January 2018

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A cluster of hydrophobic amino acid residues required for fast Na( )-channel inactivation

21 January 2018

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Structural basis for gating charge movement in the voltage sensor of a sodium channel

21 January 2018

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Overview of the voltage-gated sodium channel family

21 January 2018

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Protein acyl thioesterases (Review).

21 January 2018

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The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure

21 January 2018

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Identification of N-terminal protein acetylation and arginine methylation of the voltage-gated sodium channel in end-stage heart failure human heart

21 January 2018

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Structural parts involved in activation and inactivation of the sodium channel

21 January 2018

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21 January 2018

Identifiers

DOI

10.1007/164_2017_69

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24 February 2018

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24 February 2018