Gene drives to fight malaria: current state and future directions (Q49849235)

22 February 2018

6 references

23 March 2019

20 June 2019

19 September 2019

2 August 2022

3 October 2022

20 October 2022

Gene drives to fight malaria: current state and future directions (English)

1 reference

22 February 2018

biomedical investigative technique

3 references

23 March 2019

20 June 2019

19 September 2019

1 reference

19 September 2019

1 reference

2

1 reference

22 February 2018

Andrew Hammond

object named as

Andrew M Hammond

series ordinal

1

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language of work or name

1 reference

19 February 2018

1 reference

22 February 2018

Pathogens and Global Health

1 December 2017

6 references

23 March 2019

20 June 2019

19 September 2019

2 August 2022

3 October 2022

20 October 2022

7 references

22 February 2018

23 March 2019

20 June 2019

19 September 2019

2 August 2022

3 October 2022

20 October 2022

1-12

1 reference

22 February 2018

Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

copyright license

6 references

23 March 2019

20 June 2019

19 September 2019

2 August 2022

3 October 2022

on focus list of Wikimedia project

20 October 2022

ScienceSource

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Engineered Reciprocal Chromosome Translocations Drive High Threshold, Reversible Population Replacement in Drosophila.

1 reference

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Can CRISPR-based gene drive be confined in the wild? A question for molecular and population biology.

26 August 2018

1 reference

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The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito.

26 August 2018

1 reference

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Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria.

26 August 2018

1 reference

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Changes in the microbiota cause genetically modified Anopheles to spread in a population.

26 August 2018

1 reference

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Evaluating strategies for reversing CRISPR-Cas9 gene drives.

26 August 2018

1 reference

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Rules of the road for insect gene drive research and testing

26 August 2018

1 reference

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Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations.

26 August 2018

1 reference

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Crystallographic analyses illustrate significant plasticity and efficient recoding of meganuclease target specificity

26 August 2018

1 reference

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Overcoming evolved resistance to population-suppressing homing-based gene drives.

26 August 2018

1 reference

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The spread of Wolbachia through mosquito populations

26 August 2018

1 reference

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Local introduction and heterogeneous spatial spread of dengue-suppressing Wolbachia through an urban population of Aedes aegypti

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR-Cas9 nuclease off-targets

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Lethal gene drive selects inbreeding

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Evolution of Resistance Against CRISPR/Cas9 Gene Drive.

26 August 2018

1 reference

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26 August 2018

1 reference

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A CRISPR-Cas9 sex-ratio distortion system for genetic control

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Evolutionary biology and genetic techniques for insect control

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

The Ecology and Evolutionary Dynamics of Meiotic Drive.

26 August 2018

1 reference

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Cheating evolution: engineering gene drives to manipulate the fate of wild populations

26 August 2018

1 reference

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Cas9-triggered chain ablation of cas9 as a gene drive brake.

26 August 2018

1 reference

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High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Gene drive through a landscape: Reaction-diffusion models of population suppression and elimination by a sex ratio distorter.

26 August 2018

1 reference

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The dawn of active genetics.

26 August 2018

1 reference

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A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Rationally engineered Cas9 nucleases with improved specificity

26 August 2018

1 reference

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Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Safeguarding CRISPR-Cas9 gene drives in yeast

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

BIOSAFETY. Safeguarding gene drive experiments in the laboratory

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Stimulating Anopheles gambiae swarms in the laboratory: application for behavioural and fitness studies

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

P transposable elements in Drosophila and other eukaryotic organisms

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Genome editing. The mutagenic chain reaction: a method for converting heterozygous to homozygous mutations

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Engineering the control of mosquito-borne infectious diseases

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Stability of the wMel Wolbachia Infection following invasion into Aedes aegypti populations

26 August 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

26 August 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Concerning RNA-guided gene drives for the alteration of wild populations

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Biotechnology. Regulating gene drives

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

A synthetic sex ratio distortion system for the control of the human malaria mosquito

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

First steps towards underdominant genetic transformation of insect populations

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Heritable strategies for controlling insect vectors of disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Development of synthetic selfish elements based on modular nucleases in Drosophila melanogaster

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Homing endonucleases from mobile group I introns: discovery to genome engineering

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Reprogramming homing endonuclease specificity through computational design and directed evolution

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Genetic control of mosquitoes

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

A synthetic gene drive system for local, reversible modification and suppression of insect populations

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Optimising homing endonuclease gene drive performance in a semi-refractory species: the Drosophila melanogaster experience

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

General principles of single-construct chromosomal gene drive.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Infertility resulting from transgenic I-PpoI male Anopheles gambiae in large cage trials

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Requirements for effective malaria control with homing endonuclease genes

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Tapping natural reservoirs of homing endonucleases for targeted gene modification

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

A synthetic homing endonuclease-based gene drive system in the human malaria mosquito

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Inverse Medea as a novel gene drive system for local population replacement: a theoretical analysis

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Insect population control by homing endonuclease-based gene drive: an evaluation in Drosophila melanogaster

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

A TALE nuclease architecture for efficient genome editing

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Targeting the X chromosome during spermatogenesis induces Y chromosome transmission ratio distortion and early dominant embryo lethality in Anopheles gambiae

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Wolbachia: master manipulators of invertebrate biology

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

The population genetics of using homing endonuclease genes in vector and pest management

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Sex Ratio Distortion Caused by Meiotic Drive in a Mosquito, Culex pipiens L.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Gene drive systems for insect disease vectors

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Homing endonuclease structure and function

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Pest control by genetic manipulation of sex ratio

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Population genetics of autocidal control and strain replacement

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Sterile-Male Method of Population Control

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Site-specific selfish genes as tools for the control and genetic engineering of natural populations.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

The Genome Sequence of the Malaria Mosquito Anopheles gambiae

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Outcrossed sex allows a selfish gene to invade yeast populations.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Engineered underdominance allows efficient and economical introgression of traits into pest populations

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Stable germline transformation of the malaria mosquito Anopheles stephensi.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Homing endonucleases: keeping the house in order

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Mechanisms of intron mobility.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

The population dynamics of maternal-effect selfish genes

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

26 August 2018

Extraordinary Sex Ratios

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Genetic distortion of sex ratio in a mosquito, Aedes aegypti

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Possible use of translocations to fix desirable genes in insect pest populations.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Maternal-effect selfish genes in flour beetles

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066861

Extraordinary sex ratios. A sex-ratio theory for sex linkage and inbreeding has new implications in cytogenetics and entomology

26 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29457956

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1080/20477724.2018.1438880

1 reference

22 February 2018

PMC publication ID

6066861

0 references

1 reference

22 February 2018