Unpredictable rotational responses to L-dopa in the rat model of Parkinson's disease: the role of L-dopa pharmacokinetics and striatal dopamine depletion. (Q48945974)

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scientific article published on 13 September 2011

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English	Unpredictable rotational responses to L-dopa in the rat model of Parkinson's disease: the role of L-dopa pharmacokinetics and striatal dopamine depletion.	scientific article published on 13 September 2011

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scholarly article

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11 February 2020

Unpredictable rotational responses to L-dopa in the rat model of Parkinson's disease: the role of L-dopa pharmacokinetics and striatal dopamine depletion (English)

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Europe PubMed Central

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11 February 2020

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based on heuristic

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pharmacokinetics

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based on heuristic

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Pekka T. Männistö

6

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11 February 2020

Markus M Forsberg

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11 February 2020

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Tiina M Kääriäinen

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11 February 2020

Mikko Käenmäki

2

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11 February 2020

Niko Oinas

4

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11 February 2020

Anne Tammimäki

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11 February 2020

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13 September 2011

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11 February 2020

Basic and Clinical Pharmacology and Toxicology

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11 February 2020

110

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11 February 2020

2

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11 February 2020

162-170

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11 February 2020

Treatments for Parkinson disease--past achievements and current clinical needs

1 reference

https://api.crossref.org/works/10.1111/J.1742-7843.2011.00782.X

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Levodopa strengths and weaknesses

1 reference

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The 6-hydroxydopamine model: news from the past

1 reference

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Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance

1 reference

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Enhancement of the behavioral response to apomorphine administration following repeated treatment in the 6-hydroxydopamine-lesioned rat is temporally correlated with a rise in striatal preproenkephalin-B, but not preproenkephalin-A, gene expression

1 reference

https://api.crossref.org/works/10.1111/J.1742-7843.2011.00782.X

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The "motor complication syndrome" in rats with 6-OHDA lesions treated chronically with L-DOPA: relation to dose and route of administration

1 reference

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21 January 2018

Pharmacokinetics of levodopa

1 reference

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21 January 2018

Impact of gastric emptying on levodopa pharmacokinetics in Parkinson disease patients

1 reference

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Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Priming for l-dopa-induced dyskinesia in Parkinson's disease: a feature inherent to the treatment or the disease?

1 reference

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21 January 2018

Role of striatal L-DOPA in the production of dyskinesia in 6-hydroxydopamine lesioned rats.

1 reference

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21 January 2018

Does contraversive circling in the 6-OHDA-lesioned rat indicate an ability to induce motor complications as well as therapeutic effects in Parkinson's disease?

1 reference

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21 January 2018

Context-driven changes in L-DOPA-induced behaviours in the 6-OHDA lesioned rat.

1 reference

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21 January 2018

Direct and indirect striatal efferent pathways are differentially influenced by low and high dyskinetic drugs: behavioural and biochemical evidence

1 reference

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21 January 2018

Characterization of Enhanced Behavioral Responses tol-DOPA Following Repeated Administration in the 6-Hydroxydopamine-Lesioned Rat Model of Parkinson's Disease

1 reference

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21 January 2018

6-Hydroxydopamine-induced alterations in blood-brain barrier permeability

1 reference

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21 January 2018

Endothelial proliferation and increased blood-brain barrier permeability in the basal ganglia in a rat model of 3,4-dihydroxyphenyl-L-alanine-induced dyskinesia.

1 reference

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21 January 2018

Biotransformation of L-dopa in striatum and substantia nigra of rats with a unilateral, nigrostriatal lesion: a microdialysis study

1 reference

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21 January 2018

Effects of L-dopa on extracellular dopamine in striatum of normal and 6-hydroxydopamine-treated rats

1 reference

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21 January 2018

Peculiarities of L: -DOPA treatment of Parkinson's disease

1 reference

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21 January 2018

Mechanisms of the effects of exogenous levodopa on the dopamine-denervated striatum

1 reference

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21 January 2018

Circling behavior in rats with partial, unilateral nigro-striatal lesions: Effect of amphetamine, apomorphine, and DOPA

1 reference

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21 January 2018

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