Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia (Q48912106)

16 February 2018

http://europepmc.org/abstract/MED/8815885

title

Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia (English)

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16 February 2018

http://europepmc.org/abstract/MED/8815885

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D Giulian

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

L J Haverkamp

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

J H Yu

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

W Karshin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

D Tom

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

J Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

J Kirkpatrick

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

L M Kuo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

A E Roher

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

language of work or name

English

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publication date

1 October 1996

1 reference

16 February 2018

http://europepmc.org/abstract/MED/8815885

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

volume

16

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

issue

19

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

page(s)

6021-6037

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

15 May 2020

cites work

1 reference

12 December 2020

Cell surface morphology identifies microglia as a distinct class of mononuclear phagocyte

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12 December 2020

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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12 December 2020

Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.

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12 December 2020

Cytotoxic Effect of Brain Macrophages on Developing

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12 December 2020

Characterization of ameboid microglia isolated from developing mammalian brain.

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12 December 2020

beta-Amyloid peptide in vitro toxicity: lot-to-lot variability

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12 December 2020

Human monocytes/macrophages: NO or no NO?

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12 December 2020

Multiple and novel specificities of monoclonal antibodies O1, O4, and R-mAb used in the analysis of oligodendrocyte development

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12 December 2020

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12 December 2020

Re-evaluation of the structural organization of neuritic plaques in Alzheimer's disease.

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12 December 2020

Nitric oxide. A novel signal transduction mechanism for transcellular communication

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12 December 2020

Chemical characterization of A beta 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease.

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12 December 2020

Amino-terminal Deletions Enhance Aggregation of β-Amyloid Peptides in Vitro

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12 December 2020

Isolation and chemical characterization of Alzheimer's disease paired helical filament cytoskeletons: differentiation from amyloid plaque core protein

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12 December 2020

Brain glia release factors with opposing actions upon neuronal survival.

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12 December 2020

Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate

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12 December 2020

Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain

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12 December 2020

Sulfonated dyes attenuate the toxic effects of beta-amyloid in a structure-specific fashion

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12 December 2020

Diffuse type of senile plaques in the brains of Alzheimer-type dementia

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12 December 2020

Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein

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12 December 2020

Nonsteroidal antiinflammatory drug use in Alzheimer's disease.

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12 December 2020

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

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12 December 2020

Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

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12 December 2020

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains

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12 December 2020

Alzheimer patients and Down patients: cerebral preamyloid deposits differ ultrastructurally and histochemically from the amyloid of senile plaques

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12 December 2020

MHC class II-positive microglia in human brain: association with Alzheimer lesions

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12 December 2020

Lack of Alzheimer pathology after beta-amyloid protein injections in rat brain

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12 December 2020

beta-Amyloid precursor protein and Alzheimer's disease: the peptide plot thickens

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12 December 2020

Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro

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12 December 2020

Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study.

1 reference

12 December 2020

Down patients: extracellular preamyloid deposits precede neuritic degeneration and senile plaques.

1 reference

12 December 2020

Inflammatory mechanisms in Alzheimer's disease.

1 reference

12 December 2020

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

12 December 2020

Inhibition of mononuclear phagocytes reduces ischemic injury in the spinal cord

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12 December 2020

Cytotoxicity of microglia

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12 December 2020

Evidence that Aβ42 is the real culprit in alzheimer's disease

1 reference

12 December 2020

The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain

1 reference

12 December 2020

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

12 December 2020

The molecular pathology of Alzheimer's disease

1 reference

12 December 2020

Anti-Thy-1 immunotoxin, OX7-saporin, destroys cerebellar Purkinje cells after intraventricular injection in rats

1 reference

12 December 2020

Amyloid beta protein enhances the survival of hippocampal neurons in vitro

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12 December 2020

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

12 December 2020

Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth

1 reference

12 December 2020

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

12 December 2020

Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system

1 reference

12 December 2020

beta-Amyloid neurotoxicity: a discussion of in vitro findings

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12 December 2020

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

12 December 2020

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1 reference

12 December 2020

beta-Amyloid peptide-derived, oxygen-dependent free radicals inhibit glutamate uptake in cultured astrocytes: implications for Alzheimer's disease.

1 reference

12 December 2020

Deposits of A beta fibrils are not toxic to cortical and hippocampal neurons in vitro

1 reference

12 December 2020

Seminars in medicine of the Beth Israel Hospital, Boston. beta-Amyloid and the pathogenesis of Alzheimer's disease

1 reference

12 December 2020

Diffuse plaques do not accentuate synapse loss in Alzheimer's disease

1 reference

12 December 2020

Complement activation by beta-amyloid in Alzheimer disease

1 reference

12 December 2020

The possible contribution of microglia and macrophages to delayed neuronal death after ischemia

1 reference

12 December 2020

Morphological and biochemical analyses of amyloid plaque core proteins purified from Alzheimer disease brain tissue.

1 reference

12 December 2020

Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease

1 reference

12 December 2020

Aggregation State and Neurotoxic Properties of Alzheimer Beta-Amyloid Peptide

1 reference

12 December 2020

Glial cytokines in Alzheimer's disease: Review and pathogenic implications

1 reference

12 December 2020

Synthetic amyloid beta-protein fails to produce specific neurotoxicity in monkey cerebral cortex

1 reference

12 December 2020

New Alzheimer's therapy suggested

1 reference

12 December 2020

Anti-inflammatory drugs and Alzheimer disease.

1 reference

12 December 2020

In vivo effects of beta-amyloid implants in rodents: lack of potentiation of damage associated with transient global forebrain ischemia

1 reference

12 December 2020

Toxicity of synthetic A beta peptides and modeling of Alzheimer's disease

1 reference

12 December 2020

Reactive mononuclear phagocytes release neurotoxins after ischemic and traumatic injury to the central nervous system

1 reference

12 December 2020

The impact of microglia-derived cytokines upon gliosis in the CNS

1 reference

12 December 2020

10.1523/JNEUROSCI.16-19-06021.1996

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579176&resulttype=core&format=json

15 May 2020

1 reference