The cyclin-ubiquitin ligase activity of cyclosome/APC is jointly activated by protein kinases Cdk1-cyclin B and Plk. (Q48868322)

16 February 2018

title

The cyclin-ubiquitin ligase activity of cyclosome/APC is jointly activated by protein kinases Cdk1-cyclin B and Plk. (English)

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16 February 2018

3

Avram Hershko

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16 February 2018

Amnon Golan

1

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16 February 2018

Yana Yudkovsky

series ordinal

2

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16 February 2018

language of work or name

English

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publication date

21 February 2002

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16 February 2018

Journal of Biological Chemistry

published in

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16 February 2018

volume

277

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issue

18

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16 February 2018

page(s)

15552-15557

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16 February 2018

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

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A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

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Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast

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Whose end is destruction: cell division and the anaphase-promoting complex

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Regulation of the APC and the exit from mitosis

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Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase

21 January 2018

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Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20.

21 January 2018

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Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex

21 January 2018

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Mitotic regulation of the APC activator proteins CDC20 and CDH1

21 January 2018

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21 January 2018

The spindle checkpoint

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Waiting for anaphase: Mad2 and the spindle assembly checkpoint

21 January 2018

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Polo-like kinases: positive regulators of cell division from start to finish.

21 January 2018

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The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts

21 January 2018

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PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression.

21 January 2018

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Regulation of APC activity by phosphorylation and regulatory factors

21 January 2018

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Binding of activated cyclosome to p13(suc1). Use for affinity purification

21 January 2018

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CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

21 January 2018

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Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

21 January 2018

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Activated polo-like kinase Plx1 is required at multiple points during mitosis in Xenopus laevis

21 January 2018

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Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1

21 January 2018

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Cell cycle: reaching for a role for the Cks proteins

21 January 2018

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p13(SUC1) and the WW domain of PIN1 bind to the same phosphothreonine-proline epitope

21 January 2018

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Subunits and substrates of the anaphase-promoting complex

21 January 2018

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Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase- promoting complex at mitosis

21 January 2018

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Mitotic effects of a constitutively active mutant of the Xenopus polo-like kinase Plx1.

21 January 2018

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Role of Suc1 in the activation of the cyclosome by protein kinase Cdk1/cyclin B

21 January 2018

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M111476200

Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M111476200

Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M111476200

Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M111476200

Identifiers

DOI

10.1074/JBC.M111476200

1 reference

16 February 2018

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16 February 2018