NNK reduction pathway gene polymorphisms and risk of lung cancer. (Q48852585)

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21 March 2020

title

NNK reduction pathway gene polymorphisms and risk of lung cancer (English)

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21 March 2020

4

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21 March 2020

author name string

Jennifer L Modesto

1

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21 March 2020

Anna Hull

2

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21 March 2020

Andrea Y Angstadt

3

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21 March 2020

Carla J Gallagher

5

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21 March 2020

Philip Lazarus

6

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21 March 2020

Joshua E Muscat

7

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21 March 2020

publication date

29 June 2014

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21 March 2020

published in

Molecular Carcinogenesis

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21 March 2020

volume

54 Suppl 1

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21 March 2020

page(s)

E94-E102

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Genetic susceptibility to lung cancer--light at the end of the tunnel?

21 March 2020

cites work

1 reference

Lung cancer epidemiology, risk factors, and prevention

21 January 2018

1 reference

Profile analysis of polycyclic aromatic hydrocarbons and metal content in sediment layers of a lake

21 January 2018

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Tobacco smoke carcinogens and lung cancer

21 January 2018

1 reference

Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines

21 January 2018

1 reference

Significance of reductases in the detoxification of the tobacco-specific carcinogen NNK.

21 January 2018

1 reference

Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes

21 January 2018

1 reference

Characterization of N-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human liver: importance of UDP-glucuronosyltransferase 1A4

21 January 2018

1 reference

The influence of repair pathways on the cytotoxicity and mutagenicity induced by the pyridyloxobutylation pathway of tobacco-specific nitrosamines

21 January 2018

1 reference

Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers

21 January 2018

1 reference

Urinary levels of tobacco-specific nitrosamine metabolites in relation to lung cancer development in two prospective cohorts of cigarette smokers

21 January 2018

1 reference

The identification of 11 beta-hydroxysteroid dehydrogenase as carbonyl reductase of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

21 January 2018

1 reference

Characterization of enzymes participating in carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human placenta

21 January 2018

1 reference

Expression and NNK reducing activities of carbonyl reductase and 11beta-hydroxysteroid dehydrogenase type 1 in human lung

21 January 2018

2 references

21 January 2018

12 December 2020

Analysis of N- and O-glucuronides of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human urine

1 reference

Stereoselective metabolism and tissue retention in rats of the individual enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

21 January 2018

1 reference

Association studies of excision repair cross-complementation group 1 (ERCC1) haplotypes with lung and head and neck cancer risk in a Caucasian population

21 January 2018

1 reference

A haplotype map of the human genome

21 January 2018

1 reference

Haploview: analysis and visualization of LD and haplotype maps

21 January 2018

1 reference

Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons

21 January 2018

1 reference

Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone

21 January 2018

1 reference

Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

21 January 2018

1 reference

Diesel exhaust influences carcinogenic PAH-induced genotoxicity and gene expression in human breast epithelial cells in culture

21 January 2018

1 reference

Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).

21 January 2018

1 reference

Carbonyl reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytosolic enzymes in human liver and lung

21 January 2018

1 reference

12 December 2020

Formation and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers in vitro in mouse, rat and human tissues.

1 reference

12 December 2020

Purification and characterization of oxidoreductases-catalyzing carbonyl reduction of the tobacco-specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human liver cytosol

1 reference

12 December 2020

O-Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9.

1 reference

12 December 2020

Genetic susceptibility to lung cancer: the role of DNA damage and repair.

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12 December 2020

Tobacco smoke and involuntary smoking

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12 December 2020

Enantioselectivity of carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone by tissue fractions from human and rat and by enzymes isolated from human liver.

1 reference

12 December 2020

The Role of Human Aldo-Keto Reductases in the Metabolic Activation and Detoxication of Polycyclic Aromatic Hydrocarbons: Interconversion of PAH Catechols and PAH o-Quinones

1 reference

12 December 2020

Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.

1 reference

12 December 2020

Metabolites of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers' urine.

1 reference

12 December 2020

The Changing Cigarette

1 reference

12 December 2020

11Beta-hydroxysteroid dehydrogenase responsible for carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes.

1 reference

12 December 2020

Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.

1 reference

12 December 2020

Identifiers

DOI

10.1002/MC.22187

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24976539 AND SRC:MED&resulttype=core&format=json

release_zeot2yvhljdsvmntabxrynl3fa

21 March 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/zeot2yvhljdsvmntabxrynl3fa

24 November 2022

mapped directly with Wikidata item

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21 March 2020

PubMed publication ID

24976539

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