Unraveling the high- and low-sensitivity agonist responses of nicotinic acetylcholine receptors. (Q48667658)

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8 February 2020

title

Unraveling the high- and low-sensitivity agonist responses of nicotinic acetylcholine receptors (English)

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8 February 2020

author

Kasper Skytte Harpsøe

1

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Joergen Philip Kiaer Ahring

8 February 2020

2

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8 February 2020

Thomas Balle

6

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8 February 2020

author name string

Jeppe K Christensen

3

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8 February 2020

Marianne L Jensen

4

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8 February 2020

Dan Peters

5

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8 February 2020

language of work or name

English

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publication date

1 July 2011

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8 February 2020

published in

Journal of Neuroscience

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volume

31

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issue

30

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8 February 2020

page(s)

10759-10766

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Pharmacological similarities between native brain and heterologously expressed alpha4beta2 nicotinic receptors

8 February 2020

cites work

1 reference

12 December 2020

The Protein Data Bank

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12 December 2020

The beta subunit determines the ion selectivity of the GABAA receptor

1 reference

12 December 2020

Alternate stoichiometries of alpha4beta2 nicotinic acetylcholine receptors

1 reference

12 December 2020

Human alpha4beta2 acetylcholine receptors formed from linked subunits.

1 reference

12 December 2020

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

1 reference

12 December 2020

The benzodiazepine binding site of GABA A receptors as a target for the development of novel anxiolytics

1 reference

12 December 2020

Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations

1 reference

12 December 2020

Nicotine acts as a pharmacological chaperone to up-regulate human alpha4beta2 acetylcholine receptors

1 reference

12 December 2020

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

1 reference

12 December 2020

5-I A-85380 and TC-2559 differentially activate heterologously expressed alpha4beta2 nicotinic receptors.

1 reference

12 December 2020

alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine

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12 December 2020

Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee

1 reference

12 December 2020

Statistical potential for assessment and prediction of protein structures

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12 December 2020

Ca2 permeability of the (alpha4)3(beta2)2 stoichiometry greatly exceeds that of (alpha4)2(beta2)3 human acetylcholine receptors

1 reference

12 December 2020

An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo

1 reference

12 December 2020

Gene targeting demonstrates that alpha4 nicotinic acetylcholine receptor subunits contribute to expression of diverse [3H]epibatidine binding sites and components of biphasic 86Rb efflux with high and low sensitivity to stimulation by acetylcholine

1 reference

12 December 2020

Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution

1 reference

12 December 2020

Non-agonist-binding subunit interfaces confer distinct functional signatures to the alternate stoichiometries of the alpha4beta2 nicotinic receptor: an alpha4-alpha4 interface is required for Zn2 potentiation

1 reference

12 December 2020

NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile], a unique subtype-selective GABAA receptor positive allosteric modulator: in vitro actions, pharmacokinetic properties and in vivo anxiolytic efficacy

1 reference

12 December 2020

Pentameric concatenated (alpha4)(2)(beta2)(3) and (alpha4)(3)(beta2)(2) nicotinic acetylcholine receptors: subunit arrangement determines functional expression

1 reference

12 December 2020

Number and locations of agonist binding sites required to activate homomeric Cys-loop receptors

1 reference

12 December 2020

Human α3β4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells

1 reference

12 December 2020

Ongoing and future developments at the Universal Protein Resource

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12 December 2020

Genes encoding neuronal nicotinic acetylcholine receptors

1 reference

12 December 2020

Comparative protein modelling by satisfaction of spatial restraints

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12 December 2020

10.1523/JNEUROSCI.1509-11.2011

Identifiers

DOI

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release_nluogt6k45fpdec7rjce7dzowa

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Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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PubMed publication ID

21795528

1 reference