RGS Proteins Maintain Robustness of GPCR-GIRK Coupling by Selective Stimulation of the G Protein Subunit Gα o (Q48655186)

13 February 2018

title

RGS proteins maintain robustness of GPCR-GIRK coupling by selective stimulation of the G protein subunit Gαo (English)

1 reference

13 February 2018

RGS Proteins Maintain Robustness of GPCR-GIRK Coupling by Selective Stimulation of the G Protein Subunit Gα o (English)

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

25 December 2024

author name string

Huai-hu Chuang

1

1 reference

13 February 2018

Alexander Y. Chuang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22355188

25 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22355188

25 December 2024

publication date

21 February 2012

1 reference

13 February 2018

full work available at URL

https://www.science.org/doi/pdf/10.1126/scisignal.2002202

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

25 December 2024

1 reference

13 February 2018

volume

5

1 reference

13 February 2018

issue

212

1 reference

13 February 2018

page(s)

ra15

1 reference

13 February 2018

Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel

cites work

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

The G-protein-gated atrial K channel IKACh is a heteromultimer of two inwardly rectifying K( )-channel proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

The G protein-gated potassium current I(K,ACh) is constitutively active in patients with chronic atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Changes in I K, ACh single-channel activity with atrial tachycardia remodelling in canine atrial cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Evaluation of the role of I(KACh) in atrial fibrillation using a mouse knockout model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K channel GIRK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: The effects of subtype-selective agonists and the role of G-protein-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Mapping a barbiturate withdrawal locus to a 0.44 Mb interval and analysis of a novel null mutant identify a role for Kcnj9 (GIRK3) in withdrawal from pentobarbital, zolpidem, and ethanol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

A pervasive mechanism for analgesia: activation of GIRK2 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Absence and rescue of morphine withdrawal in GIRK/Kir3 knock-out mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

A mouse model for Down syndrome exhibits learning and behaviour deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

The beta gamma subunits of GTP-binding proteins activate the muscarinic K channel in heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Cellular modelling: experiments and simulation to develop a physiological model of G-protein control of muscarinic K channels in mammalian atrial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

The regulator of G protein signaling family

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

RGS8 accelerates G-protein-mediated modulation of K currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

RGS7 and RGS8 differentially accelerate G protein-mediated modulation of K currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Coordinating speed and amplitude in G-protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Cellular mechanisms that determine selective RGS protein regulation of G protein-coupled receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Cellular regulation of RGS proteins: modulators and integrators of G protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

New roles for RGS2, 5 and 8 on the ratio-dependent modulation of recombinant GIRK channels expressed in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Regulators of G-protein signaling form a quaternary complex with the agonist, receptor, and G-protein. A novel explanation for the acceleration of signaling activation kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Endogenous RGS proteins enhance acute desensitization of GABA(B) receptor-activated GIRK currents in HEK-293T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Endogenous RGS proteins facilitate dopamine D(2S) receptor coupling to G(alphao) proteins and Ca2 responses in CHO-K1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

HL-1 cells express an inwardly rectifying K current activated via muscarinic receptors comparable to that in mouse atrial myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Overexpression of beta 1 and beta 2 adrenergic receptors in rat atrial myocytes. Differential coupling to G protein-gated inward rectifier K( ) channels via G(s) and G(i)/o.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Changes in striatal signaling induce remodeling of RGS complexes containing Gbeta5 and R7BP subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Mechanism of RGS4, a GTPase-activating Protein for G Protein α Subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Interaction between the RGS domain of RGS4 with G protein alpha subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Muscarinic activation of inwardly rectifying K( ) conductance reduces EPSPs in rat hippocampal CA1 pyramidal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Kinetic Scaffolding Mediated by a Phospholipase C- and Gq Signaling Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Regulators of G-protein signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Determination of the contact energies between a regulator of G protein signaling and G protein subunits and phospholipase C beta 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Measurement of heterotrimeric G-protein and regulators of G-protein signaling interactions by time-resolved fluorescence resonance energy transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Molecular architecture of G o and the structural basis for RGS16-mediated deactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gbeta5 complex and accelerates inactivation of the mGluR6-G(o) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

G protein-coupled inwardly rectifying K channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

21 January 2018

3

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Kir3-based inward rectifier potassium current: potential role in atrial tachycardia remodeling effects on atrial repolarization and arrhythmias

25 December 2024

6

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Decreased cocaine self-administration in Kir3 potassium channel subunit knockout mice

25 December 2024

12

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors.

25 December 2024

23

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

RGS expression rate-limits recovery of rod photoresponses

25 December 2024

26

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

RGS expression level precisely regulates the duration of rod photoresponses

25 December 2024

28

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

RGS9, a GTPase accelerator for phototransduction

25 December 2024

30

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Mutational analysis of the Asn residue essential for RGS protein binding to G-proteins

25 December 2024

54

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

IRK(1-3) and GIRK(1-4) inwardly rectifying K channel mRNAs are differentially expressed in the adult rat brain

25 December 2024

60

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat Brain

25 December 2024

61

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Phospholipase C-beta1 directly accelerates GTP hydrolysis by Galphaq and acceleration is inhibited by Gbeta gamma subunits

25 December 2024

64

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions

25 December 2024

70

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.

25 December 2024

72

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2002202

25 December 2024

Identifiers

1 reference

13 February 2018

1 reference

13 February 2018