Interleukin-6 Trans-Signaling Pathway Promotes Immunosuppressive Myeloid-Derived Suppressor Cells via Suppression of Suppressor of Cytokine Signaling 3 in Breast Cancer (Q48540777)

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English	Interleukin-6 Trans-Signaling Pathway Promotes Immunosuppressive Myeloid-Derived Suppressor Cells via Suppression of Suppressor of Cytokine Signaling 3 in Breast Cancer	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

12 February 2018

http://europepmc.org/abstract/PMC/5736866

Interleukin-6 Trans-Signaling Pathway Promotes Immunosuppressive Myeloid-Derived Suppressor Cells via Suppression of Suppressor of Cytokine Signaling 3 in Breast Cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

12 February 2018

http://europepmc.org/abstract/PMC/5736866

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author name string

Mengmeng Jiang

1

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Jieying Chen

2

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Wenwen Zhang

3

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Rui Zhang

4

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Yingnan Ye

5

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Pengpeng Liu

6

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Wenwen Yu

7

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Feng Wei

8

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Europe PubMed Central

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Xiubao Ren

9

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Jinpu Yu

10

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

publication date

15 December 2017

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Europe PubMed Central

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

Frontiers in Immunology

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12 February 2018

http://europepmc.org/abstract/PMC/5736866

8

1 reference

Europe PubMed Central

PMC publication ID

12 February 2018

http://europepmc.org/abstract/PMC/5736866

1840

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Europe PubMed Central

PMC publication ID

12 February 2018

http://europepmc.org/abstract/PMC/5736866

Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling

1 reference

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22 May 2018

Dysregulation of SOCS-Mediated Negative Feedback of Cytokine Signaling in Carcinogenesis and Its Significance in Cancer Treatment

1 reference

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Tumor Microenvironment, a Paradigm in Hepatocellular Carcinoma Progression and Therapy

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22 May 2018

Tumor microenvironment-mediated chemoresistance in breast cancer.

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22 May 2018

Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies

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22 May 2018

Interleukin-10 attenuates tumour growth by inhibiting interleukin-6/signal transducer and activator of transcription 3 signalling in myeloid-derived suppressor cells

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22 May 2018

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

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22 May 2018

Phenotype, development, and biological function of myeloid-derived suppressor cells

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22 May 2018

The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells.

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Cancer associated fibroblasts have phenotypic and functional characteristics similar to the fibrocytes that represent a novel MDSC subset

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22 May 2018

Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex

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22 May 2018

Myeloid-Derived Suppressor Cells: Critical Cells Driving Immune Suppression in the Tumor Microenvironment

1 reference

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22 May 2018

SOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor Cells

1 reference

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22 May 2018

IL-6-stimulated CD11b CD14 HLA-DR- myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus

1 reference

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22 May 2018

Noncanonical NF-κB activation mediates STAT3-stimulated IDO upregulation in myeloid-derived suppressor cells in breast cancer

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22 May 2018

Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation

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22 May 2018

Inhibition of IL-6 family cytokines by SOCS3.

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22 May 2018

Interleukin-6: from basic biology to selective blockade of pro-inflammatory activities

1 reference

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Myeloid-derived suppressor cells predict survival of patients with advanced melanoma: comparison with regulatory T cells and NY-ESO-1- or melan-A-specific T cells

1 reference

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Targeting interleukin-6 in inflammatory autoimmune diseases and cancers

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22 May 2018

A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 trans-signaling in a murine model

1 reference

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Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases

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Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner

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22 May 2018

Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer

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Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer.

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Significance of IL-6 in the transition of hormone-resistant prostate cancer and the induction of myeloid-derived suppressor cells

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SOCS, Inflammation, and Autoimmunity

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Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity

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Upregulated expression of indoleamine 2, 3-dioxygenase in primary breast cancer correlates with increase of infiltrated regulatory T cells in situ and lymph node metastasis

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Role of SOCS1 in tumor progression and therapeutic application

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Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

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Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13

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Myeloid-derived suppressor cells as regulators of the immune system

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https://pubmed.ncbi.nlm.nih.gov/29326716

12 December 2020

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Identifiers

10.3389/FIMMU.2017.01840

1 reference

Europe PubMed Central

PMC publication ID

12 February 2018

http://europepmc.org/abstract/PMC/5736866

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 February 2018

http://europepmc.org/abstract/PMC/5736866

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 February 2018

http://europepmc.org/abstract/PMC/5736866

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