Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease. (Q48540299)

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21 January 2020

title

Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease (English)

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21 January 2020

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21 January 2020

author name string

L B Moran

2

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21 January 2020

M E Kalaitzakis

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21 January 2020

M Deprez

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21 January 2020

D T Dexter

5

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21 January 2020

R K B Pearce

6

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21 January 2020

M B Graeber

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21 January 2020

publication date

13 May 2006

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21 January 2020

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21 January 2020

volume

7

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21 January 2020

issue

3

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21 January 2020

page(s)

139-148

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Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: statistical reliability and functional correlation

21 January 2020

cites work

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Crossref

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Proteasome inhibition alters neural mitochondrial homeostasis and mitochondria turnover

21 January 2018

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12 December 2020

Alpha-synuclein-immunoreactive cortical Lewy bodies are associated with cognitive impairment in Parkinson's disease.

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Glia cell number modulates sensitivity to MPTP in mice

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Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

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Altered proteasomal function in sporadic Parkinson's disease

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

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The human genome: gene expression profiling and schizophrenia

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

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Animal models of Parkinson's disease.

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12 December 2020

Hormones are key actors in gene x environment interactions programming the vulnerability to Parkinson's disease: glia as a common final pathway.

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12 December 2020

Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: glia dictates resistance versus vulnerability to neurodegeneration.

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Mitochondrial dysfunction in Parkinson's disease

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12 December 2020

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

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Neuropathology of the Substantia nigra

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Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease

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Lewy bodies in Betz cells of the motor cortex in a patient with Parkinson's disease

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The role of alpha-synuclein in Parkinson's disease: insights from animal models

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

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A possible role for humoral immunity in the pathogenesis of Parkinson's disease

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The age of onset of Parkinson's disease: etiological implications

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Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells

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NACP/alpha-synuclein-positive filamentous inclusions in astrocytes and oligodendrocytes of Parkinson's disease brains

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Proteasome inhibition causes nigral degeneration with inclusion bodies in rats

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The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells

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'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns

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Expression of NAD(P)H:quinone oxidoreductase in the normal and Parkinsonian substantia nigra

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The anatomy and pigmentation of the human substantia nigra in relation to selective neuronal vulnerability

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Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

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Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease.

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12 December 2020

The ubiquitin pathway in Parkinson's disease

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12 December 2020

p53-mediated mitochondrial dysfunction by proteasome inhibition in dopaminergic SH-SY5Y cells

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12 December 2020

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12 December 2020

Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease

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12 December 2020

Singular value decomposition for genome-wide expression data processing and modeling

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Microglial activation and dopamine terminal loss in early Parkinson's disease

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12 December 2020

Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

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12 December 2020

Genomics. Microarrays--guilt by association

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12 December 2020

Familial Parkinson's disease: a hint to elucidate the mechanisms of nigral degeneration

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Parkinson's disease and brain mitochondrial dysfunction: a functional phosphorus magnetic resonance spectroscopy study

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Effect of proteasome inhibitor on cultured mesencephalic dopaminergic neurons

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Monkey model of Parkinson's disease

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Genes and parkinsonism

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The cast of molecular characters in Parkinson's disease: felons, conspirators, and suspects

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Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses

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Mitochondrial complex I deficiency in Parkinson's disease

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Two novel point mutations of mitochondrial tRNA genes in histologically confirmed Parkinson disease

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Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

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12 December 2020

Parkinson's disease: an update*

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12 December 2020