Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania. (Q48433009)

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29 December 2019

title

Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania (English)

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Jos Prickaerts

1

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Dieder Moechars

2

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Kim Cryns

3

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Ilse Lenaerts

4

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Hansfried van Craenendonck

5

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Ilse Goris

6

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Guy Daneels

7

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J Adriaan Bouwknecht

8

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Thomas Steckler

9

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language of work or name

English

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publication date

1 August 2006

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29 December 2019

published in

Journal of Neuroscience

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volume

26

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issue

35

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29 December 2019

page(s)

9022-9029

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The effect of lithium administration in animal models of depression: a short review

29 December 2019

cites work

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Glucocorticoids and depression

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Insulin-like growth factor 1 regulates developing brain glucose metabolism

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Enhancement of hippocampal neurogenesis by lithium

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Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.

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The role of dopamine in the mechanism of action of antidepressant drugs

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A concise review on the therapeutics of obesity

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Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists

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Hyperactivity and impaired response habituation in hyperdopaminergic mice

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The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

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GSK3 takes centre stage more than 20 years after its discovery

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Sensorimotor gating deficits in bipolar disorder patients with acute psychotic mania.

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Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection

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BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents

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Neonatal neuronal overexpression of glycogen synthase kinase-3 beta reduces brain size in transgenic mice.

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Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia

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Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system

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GSK-3: tricks of the trade for a multi-tasking kinase

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Alleviating the suppression of glycogen synthase kinase-3beta by Akt leads to the phosphorylation of cAMP-response element-binding protein and its transactivation in intact cell nuclei

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A single course of prenatal betamethasone in the rat alters postnatal brain cell proliferation but not apoptosis.

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In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3.

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Nicotine and ethanol enhancements of acoustic startle reflex are mediated in part by dopamine in C57BL/6J mice

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Signal transduction and genes-to-behaviors pathways in psychiatric diseases

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12 December 2020

[Schizophrenia and eating disorders]

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Glycogen synthase kinase-3 as drug target: from wallflower to center of attention

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Glycogen synthase kinase-3: a target for novel bipolar disorder treatments.

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Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

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12 December 2020

Perspectives for the development of animal models of bipolar disorder

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Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

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12 December 2020

Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus.

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12 December 2020

Habituation of acoustic startle is disrupted by psychotomimetic drugs: differential dependence on dopaminergic and nitric oxide modulatory mechanisms

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12 December 2020

AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test

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12 December 2020

The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels

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12 December 2020

Dysregulation of striatal dopamine signaling by amphetamine inhibits feeding by hungry mice

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12 December 2020

Body weight is regulated by the brain: a link between feeding and emotion

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12 December 2020

Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators

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12 December 2020

Psychiatric and medical comorbidities of bipolar disorder

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12 December 2020

Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs

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Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene

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An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

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Amphetamine disruption of prepulse inhibition of acoustic startle is reversed by depletion of mesolimbic dopamine

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Neural and developmental actions of lithium: a unifying hypothesis

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Lithium induces rapid relief of depression in tricyclic antidepressant drug non-responders

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12 December 2020

Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

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12 December 2020

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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12 December 2020

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.

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12 December 2020

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

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12 December 2020

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

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12 December 2020

A molecular mechanism for the effect of lithium on development

1 reference

12 December 2020

Mechanism of activation of protein kinase B by insulin and IGF-1

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12 December 2020

In vivo neurogenesis is inhibited by neutralizing antibodies to basic fibroblast growth factor

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12 December 2020

Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity

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12 December 2020

Signal Transduction and Genes-to-Behaviors Pathways in Psychiatric Diseases

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12 December 2020

10.1523/JNEUROSCI.5216-05.2006

Identifiers

DOI

1 reference

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29 December 2019

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29 December 2019

PubMed publication ID

16943560

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