Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation (Q48370319)

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scientific article published on 5 September 2016

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English	Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation	scientific article published on 5 September 2016

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11 February 2018

http://europepmc.org/abstract/MED/27595325

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation (English)

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11 February 2018

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atherosclerosis

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Konstantinos Stellos

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Reinier A. Boon

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Lars Maegdefessel

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Harald Schwalbe

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Stefanie Dimmeler

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Xintian You

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Oliver Rossbach

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Oliver Rossbach

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Andreas M Zeiher

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Jes-Niels Boeckel

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Jes-Niels Boeckel

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Yosif Manavski

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Nicolas Jaé

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Kimon Stamatelopoulos

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Kimon Stamatelopoulos

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Aikaterini Gatsiou

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Aikaterini Gatsiou

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Ljubica Perisic

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Ljubica Perisic Matic

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Carolin Amrhein

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Carolin Amrhein

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David John

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Federica Francesca Lunella

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Frangiska Sigala

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Boris Fürtig

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Anders Franco-Cereceda

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Wei Chen

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Albrecht Bindereif

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5 September 2016

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Nature Medicine

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1140-1150

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Editor meets silencer: crosstalk between RNA editing and RNA interference

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Elucidating the inosinome: global approaches to adenosine-to-inosine RNA editing

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A-to-I editing of coding and non-coding RNAs by ADARs

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Systematic identification of abundant A-to-I editing sites in the human transcriptome

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Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome

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Alu elements shape the primate transcriptome by cis-regulation of RNA editing

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Genome-wide analysis of Alu editability

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Alu elements as regulators of gene expression

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Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks

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Widespread RNA editing of embedded alu elements in the human transcriptome

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Deficiency of the cysteine protease cathepsin S impairs microvessel growth

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Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.

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Cathepsin S activity regulates antigen presentation and immunity

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Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice

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RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

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Specialized roles for cysteine cathepsins in health and disease.

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Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo

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Association between serum cathepsin S and mortality in older adults

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Regulation of alternative splicing by RNA editing

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10.1038/NM.4172

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27595325

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27595325

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