Investigation of the Subcellular Neurotoxicity of Amyloid-β Using a Device Integrating Microfluidic Perfusion and Chemotactic Guidance (Q48340658)

10 February 2018

http://europepmc.org/abstract/MED/28121396

title

Investigation of the Subcellular Neurotoxicity of Amyloid-β Using a Device Integrating Microfluidic Perfusion and Chemotactic Guidance (English)

1 reference

10 February 2018

http://europepmc.org/abstract/MED/28121396

0 references

1 reference

1 reference

1 reference

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Peng Shi

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Wei Li

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Zhen Xu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Bingzhe Xu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Chung Yuen Chan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Xudong Lin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Ying Wang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Ganchao Chen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Zhigang Wang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Qiuju Yuan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Guangyu Zhu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

Wutian Wu

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

publication date

25 January 2017

1 reference

10 February 2018

http://europepmc.org/abstract/MED/28121396

published in

Advanced Healthcare Materials

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

describes a project that uses

10 June 2020

1 reference

Forecasting the global burden of Alzheimer’s disease

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Amyloid β-peptide (1-42)-induced oxidative stress in Alzheimer disease: importance in disease pathogenesis and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Testing Aβ toxicity on primary CNS cultures using drug-screening microfluidic chips.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Amyloid beta: multiple mechanisms of toxicity and only some protective effects?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Amyloid-beta precursor protein processing in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

A microfluidic culture platform for CNS axonal injury, regeneration and transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Combined microfluidics/protein patterning platform for pharmacological interrogation of axon pathfinding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Microfluidic local perfusion chambers for the visualization and manipulation of synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Synapse microarray identification of small molecules that enhance synaptogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Site-specific differentiation of neural stem cell regulated by micropatterned multicomponent interfaces.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

High-throughput mapping of brain-wide activity in awake and drug-responsive vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Autonomous system for cross-organ investigation of ethanol-induced acute response in behaving larval zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

β-Amyloid is transmitted via neuronal connections along axonal membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Axon guidance by diffusible chemoattractants: a gradient of netrin protein in the developing spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Semaphorin3A regulates neuronal polarization by suppressing axon formation and promoting dendrite growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Semaphorin 3A is a chemoattractant for cortical apical dendrites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2 accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Internalization of beta-amyloid peptide by primary neurons in the absence of apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

TgCRND8 amyloid precursor protein transgenic mice exhibit an altered gamma-secretase processing and an aggressive, additive amyloid pathology subject to immunotherapeutic modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Impaired β-amyloid secretion in Alzheimer's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Beta-amyloid monomers are neuroprotective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Stable size distribution of amyloid plaques over the course of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Nucleation of protein fibrillation by nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

A microfluidic chamber for analysis of neuron-to-cell spread and axonal transport of an alpha-herpesvirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Culturing hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

Chemical calcium indicators

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/ADHM.201600895

21 January 2018

Identifiers

DOI

10.1002/ADHM.201600895

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28121396 AND SRC:MED&resulttype=core&format=json

10 June 2020

1 reference