Hyperammonemia alters the modulation by different neurosteroids of the glutamate-nitric oxide-cyclic GMP pathway through NMDA- GABAA - or sigma receptors in cerebellum in vivo. (Q48258716)

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English	Hyperammonemia alters the modulation by different neurosteroids of the glutamate-nitric oxide-cyclic GMP pathway through NMDA- GABAA - or sigma receptors in cerebellum in vivo.	scientific article

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20 February 2020

Hyperammonemia alters the modulation by different neurosteroids of the glutamate-nitric oxide-cyclic GMP pathway through NMDA- GABAA - or sigma receptors in cerebellum in vivo (English)

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20 February 2020

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20 February 2020

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Alba González-Usano

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17 February 2013

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Journal of Neurochemistry

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20 February 2020

The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy

1 reference

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The neurosteroid system: implication in the pathophysiology of hepatic encephalopathy

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Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma

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A simple animal model of hyperammonemia

1 reference

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Neurosteroids: a novel function of the brain

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Neurosteroids: endogenous regulators of the GABA(A) receptor

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Metabotropic glutamate receptor 5 modulates the nitric oxide-cGMP pathway in cerebellum in vivo through activation of AMPA receptors

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Hypolocomotion in rats with chronic liver failure is due to increased glutamate and activation of metabotropic glutamate receptors in substantia nigra

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Inflammation and hepatic encephalopathy: ibuprofen restores learning ability in rats with portacaval shunts.

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Hyperammonemia increases GABAergic tone in the cerebellum but decreases it in the rat cortex

1 reference

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Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo

1 reference

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Neurosteroids: biosynthesis and function of these novel neuromodulators

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Characterization and measurement of dehydroepiandrosterone sulfate in rat brain

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Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum

1 reference

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Restoration of learning ability in hyperammonemic rats by increasing extracellular cGMP in brain

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Actions of 3 alpha,5 alpha-tetrahydrodeoxycorticosterone on single neurones of the mesencephalic reticular formation in the rat.

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Desensitization of AMPA receptors and AMPA-NMDA receptor interaction: an in vivo cyclic GMP microdialysis study in rat cerebellum

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In vivo microdialysis study of GABAA and GABaB receptors modulating the glutamate receptor/NO/ cyclic GMP pathway in the rat hippocampus

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Benzodiazepine-sensitive GABA(A) receptors limit the activity of the NMDA/NO/cyclic GMP pathway: a microdialysis study in the cerebellum of freely moving rats

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Neurobiology of ammonia.

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Effects of progesterone administration and APPswe PSEN1Deltae9 mutation for cognitive performance of mid-aged mice

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Chronic hyperammonemia impairs the glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo

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GABAergic neurosteroids mediate the effects of ethanol on long-term potentiation in rat hippocampal slices

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Brain neurosteroids are 4th generation neuromessengers in the brain: cell biophysical analysis of steroid signal transduction

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Neurosteroids and GABAA receptor function.

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Increasing the function of the glutamate-nitric oxide-cyclic guanosine monophosphate pathway increases the ability to learn a Y-maze task

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Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

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Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids

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The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease

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Dehydroepiandrosterone sulfate attenuates dizocilpine-induced learning impairment in mice via sigma 1-receptors

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Neuroactive neurosteroids as endogenous effectors for the sigma1 (sigma1) receptor: pharmacological evidence and therapeutic opportunities

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Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus

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Opipramol, a potent sigma ligand, is an anti-ischemic agent: neurochemical evidence for an interaction with the N-methyl-D-aspartate receptor complex in vivo by cerebellar cGMP measurements

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Neurocognitive deficits in schizophrenia are associated with alterations in blood levels of neurosteroids: a multiple regression analysis of findings from a double-blind, randomized, placebo-controlled, crossover trial with DHEA.

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Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy

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Sigma1 receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory

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Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration

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Neurosteroid modulation of GABAergic neurotransmission in the central amygdala: a role for NMDA receptors

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Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

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Role of nitric oxide and cyclic GMP in the dizocilpine-induced impairment of spontaneous alternation behavior in mice

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10.1111/JNC.12119

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23227932 AND SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23227932 AND SRC:MED&resulttype=core&format=json

20 February 2020

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