The role of the thioredoxin/thioredoxin reductase system in the metabolic syndrome: towards a possible prognostic marker? (Q48256915)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29327078 AND SRC:MED&resulttype=core&format=json

9 April 2020

title

The role of the thioredoxin/thioredoxin reductase system in the metabolic syndrome: towards a possible prognostic marker? (English)

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9 April 2020

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2

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9 April 2020

Alexey A Tinkov

1

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9 April 2020

Anatoly V Skalny

3

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9 April 2020

Margarita G Skalnaya

5

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9 April 2020

6

Salvatore Chirumbolo

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9 April 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29327078 AND SRC:MED&resulttype=core&format=json

author name string

Arne Holmgren

4

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9 April 2020

Jan Aaseth

7

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9 April 2020

publication date

11 January 2018

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Cellular and Molecular Life Sciences

9 April 2020

published in

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9 April 2020

volume

75

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9 April 2020

issue

9

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9 April 2020

page(s)

1567-1586

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Synergy between sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation

9 April 2020

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Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis

21 January 2018

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Elevation of serum thioredoxin levels in patients with type 2 diabetes

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Increased plasma levels of thioredoxin in patients with glucose intolerance

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Oxidative stress and cellular stress response in diabetic nephropathy.

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Thioredoxin-1 overexpression in transgenic mice attenuates streptozotocin-induced diabetic osteopenia: a novel role of oxidative stress and therapeutic implications.

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Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes

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Transgenic expression of antioxidant protein thioredoxin in pancreatic beta cells prevents progression of type 2 diabetes mellitus.

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21 January 2018

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Diabetes impairs exercise training-associated thioredoxin response and glutathione status in rat brain

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Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets

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21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

TXNIP regulates peripheral glucose metabolism in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Knockdown of thioredoxin-interacting protein ameliorates high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Protein glutathionylation in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Glutathione synthesis and its role in redox signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Protein denitrosylation: enzymatic mechanisms and cellular functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin-interacting protein is killing my beta-cells!

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Dietary wolfberry ameliorates retinal structure abnormalities in db/db mice at the early stage of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Glutaredoxin regulates nuclear factor kappa-B and intercellular adhesion molecule in Müller cells: model of diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Possible role for the thioredoxin system in the protective effects of probucol in the pancreatic islets of diabetic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Molecular aspects of lipoic acid in the prevention of diabetes complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Compendium of the antidiabetic effects of supranutritional selenate doses. In vivo and in vitro investigations with type II diabetic db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Arsenic exposure and type 2 diabetes: a systematic review of the experimental and epidemiological evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

The potential biological mechanisms of arsenic-induced diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Arsenic and selenium toxicity and their interactive effects in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Methylglyoxal causes dysfunction of thioredoxin and thioredoxin reductase in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin-1 gene therapy enhances angiogenic signaling and reduces ventricular remodeling in infarcted myocardium of diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Oxidative stress and hypertension: current concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Emerging potential of thioredoxin and thioredoxin interacting proteins in various disease conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Effects of long-term selenium deficiency on glutathione peroxidase and thioredoxin reductase activities and expressions in rat aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin interacting protein genetic variation is associated with diabetes and hypertension in the Brazilian general population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Genetic variation in thioredoxin interacting protein (TXNIP) is associated with hypertriglyceridaemia and blood pressure in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Enhanced oxidative stress and impaired thioredoxin expression in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Attenuation of angiotensin II-induced vascular dysfunction and hypertension by overexpression of Thioredoxin 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Mitochondrial Thioredoxin: novel regulator for NADPH oxidase and angiotensin II-induced hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Differential regulation of thioredoxin and NAD(P)H oxidase by angiotensin II in male and female mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin reductase inhibition reduces relaxation by increasing oxidative stress and s-nitrosylation in mouse aorta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Augmented S-nitrosylation contributes to impaired relaxation in angiotensin II hypertensive mouse aorta: role of thioredoxin reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Endothelial cells negatively modulate reactive oxygen species generation in vascular smooth muscle cells: role of thioredoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin reductase regulates the induction of haem oxygenase-1 expression in aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin-1 gene delivery induces heme oxygenase-1 mediated myocardial preservation after chronic infarction in hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Nitric oxide-dependent suppression of thioredoxin-interacting protein expression enhances thioredoxin activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin restores nitric oxide-induced inhibition of protein kinase C activity in lung endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

The role of oxidative stress in the pathophysiology of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Selenium and coenzyme Q10 interrelationship in cardiovascular diseases--A clinician's point of view

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Less increase of copeptin and MR-proADM due to intervention with selenium and coenzyme Q10 combined: Results from a 4-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Levels of sP-selectin and hs-CRP Decrease with Dietary Intervention with Selenium and Coenzyme Q10 Combined: A Secondary Analysis of a Randomized Clinical Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Decreased serum levels of thioredoxin in patients with coronary artery disease plus hyperhomocysteinemia is strongly associated with the disease severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Increased oxidative stress with elevated serum thioredoxin level in patients with coronary spastic angina

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin-1/peroxiredoxin-1 as sensors of oxidative stress mediated by NADPH oxidase activity in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Serum thioredoxin and alpha-tocopherol concentrations in patients with major risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Imbalance in superoxide dismutase/thioredoxin reductase activities in hypercholesterolemic subjects: relationship with low density lipoprotein oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Enhanced reduction in oxidative stress and altered glutathione and thioredoxin system response to unsaturated fatty acid load in familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Expression of glutaredoxin in human coronary arteries: its potential role in antioxidant protection against atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin in coronary culprit lesions: possible relationship to oxidative stress and intraplaque hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Increased plasma levels of thioredoxin in patients with coronary spastic angina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Plasma thioredoxin levels and platelet aggregability in patients with acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Laser microdissection-based analysis of hypoxia- and thioredoxin-related genes in human stable carotid plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Disturbed flow enhances inflammatory signaling and atherogenesis by increasing thioredoxin-1 level in endothelial cell nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Resveratrol enhances neovascularization in the infarcted rat myocardium through the induction of thioredoxin-1, heme oxygenase-1 and vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Resveratrol alleviate hypoxic pulmonary hypertension via anti-inflammation and anti-oxidant pathways in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Txnip ablation reduces vascular smooth muscle cell inflammation and ameliorates atherosclerosis in apolipoprotein E knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Macrophages in the Pathogenesis of Atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Thioredoxin-1 promotes anti-inflammatory macrophages of the M2 phenotype and antagonizes atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Suppression of the pro-inflammatory NLRP3/interleukin-1β pathway in macrophages by the thioredoxin reductase inhibitor auranofin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1beta expression in human monocyte-derived macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Oxidized LDL induces a coordinated up-regulation of the glutathione and thioredoxin systems in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Selenium effect on selenoprotein transcriptome in chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-018-2745-8

Differential reactivity of the functional sulfhydryl groups of cysteine-32 and cysteine-35 present in the reduced form of thioredoxin from Escherichia coli

21 January 2018

1 reference

12 December 2020

Expression of thioredoxin is enhanced in atherosclerotic plaques and during neointima formation in rat arteries

1 reference

12 December 2020

Thioredoxin reductase is the major selenoprotein expressed in human umbilical-vein endothelial cells and is regulated by protein kinase C

1 reference

12 December 2020

Truncated thioredoxin is a mitogenic cytokine for resting human peripheral blood mononuclear cells and is present in human plasma

1 reference

12 December 2020

Induction of thioredoxin reductase gene expression by peroxynitrite in human umbilical vein endothelial cells

1 reference

12 December 2020

Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease

1 reference

12 December 2020

The thioredoxin-thioredoxin reductase system: over-expression in human cancer

1 reference

12 December 2020

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES. IV. ISOLATION AND CHARACTERIZATION OF THIOREDOXIN, THE HYDROGEN DONOR FROM ESCHERICHIA COLI B

1 reference

12 December 2020

Thioredoxin and atherosclerosis

1 reference

12 December 2020

Increased lipogenesis and fatty acid reesterification contribute to hepatic triacylglycerol stores in hyperlipidemic Txnip-/- mice

1 reference

12 December 2020

Plasma thioredoxin levels in patients with unstable angina

1 reference

12 December 2020

Elevation of serum thioredoxin levels in patients with nonalcoholic steatohepatitis

1 reference

12 December 2020

Metabolic syndrome scientific statement by the American Heart Association and the National Heart, Lung, and Blood Institute

1 reference

12 December 2020

Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice

1 reference

12 December 2020

[Role of oxidative stress in non-alcoholic steatohepatitis]

1 reference

12 December 2020

The thioredoxin system in cancer-introduction to a thematic volume of Seminars in Cancer Biology

1 reference

12 December 2020

Discordant Response of Glutathione and Thioredoxin Systems in Human Hypertension?

1 reference

12 December 2020

TXNIP Links Redox Circuitry to Glucose Control

1 reference

12 December 2020

Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2

1 reference

12 December 2020

Nonalcoholic fatty liver disease: a manifestation of the metabolic syndrome.

1 reference

12 December 2020

Molecular scanning of the gene for thioredoxin, an antioxidative and antiapoptotic protein, and genetic susceptibility to type 1 diabetes

1 reference

12 December 2020

The metabolic syndrome: a gathering challenge in a time of abundance

1 reference

12 December 2020

Thioredoxin reductase 1 upregulates MCP-1 release in human endothelial cells

1 reference

12 December 2020

Olmesartan, a novel angiotensin II type 1 receptor antagonist, reduces severity of atherosclerosis in apolipoprotein E deficient mice associated with reducing superoxide production

1 reference

12 December 2020

Obesity-induced diabetes in mouse strains treated with gold thioglucose: a novel animal model for studying β-cell dysfunction

1 reference

12 December 2020

Inhibition of the thioredoxin system in the brain and liver of zebra-seabreams exposed to waterborne methylmercury

1 reference

12 December 2020

Polymorphisms of antioxidant enzymes, blood pressure and risk of hypertension

1 reference

12 December 2020

Treatments with sodium selenate or doxycycline offset diabetes-induced perturbations of thioredoxin-1 levels and antioxidant capacity

1 reference

12 December 2020

Correcting a marginal riboflavin deficiency improves hematologic status in young women in the United Kingdom (RIBOFEM)

1 reference

12 December 2020

Selenium homeostasis and induction of thioredoxin reductase during long term selenite supplementation in the rat

1 reference

12 December 2020

Administration of recombinant human thioredoxin‐1 significantly delays and prevents autoimmune diabetes in nonobese diabetic mice through modulation of autoimmunity

1 reference

12 December 2020

Oxidative stress, glutathione status, sirtuin and cellular stress response in type 2 diabetes

1 reference

12 December 2020

Human atherosclerotic plaque lipid extract impairs the antioxidant defense capacity of monocytes

1 reference

12 December 2020

Differences in the redox status of human visceral and subcutaneous adipose tissues--relationships to obesity and metabolic risk

1 reference

12 December 2020

Effect of selenium on selenoprotein expression in the adipose tissue of chickens

1 reference

12 December 2020

Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not w

1 reference

12 December 2020

The antiatherogenic effect of bixin in hypercholesterolemic rabbits is associated to the improvement of lipid profile and to its antioxidant and anti-inflammatory effects

1 reference

12 December 2020

Glycemic control and oxidative stress markers and their relationship with the thioredoxin interacting protein (TXNIP) gene in type 2 diabetic patients

1 reference

12 December 2020

Retrospective analysis of the relationship between elevated plasma levels of TXNIP and carotid intima-media thickness in subjects with impaired glucose tolerance and early Type 2 diabetes mellitus

1 reference

12 December 2020

Thioredoxin 1 in Prostate Tissue Is Associated with Gleason Score, Erythrocyte Antioxidant Enzyme Activity, and Dietary Antioxidants

1 reference

12 December 2020

Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients

1 reference

12 December 2020

Cardiovascular disease: Thioredoxin lowers hypertension

1 reference

12 December 2020

10.1007/S00018-018-2745-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29327078 AND SRC:MED&resulttype=core&format=json

9 April 2020

1 reference