Combined sublethal irradiation and agonist anti-CD40 enhance donor T cell accumulation and control of autochthonous murine pancreatic tumors. (Q48248569)

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scientific article published on 13 January 2018

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English	Combined sublethal irradiation and agonist anti-CD40 enhance donor T cell accumulation and control of autochthonous murine pancreatic tumors.	scientific article published on 13 January 2018

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29332158 AND SRC:MED&resulttype=core&format=json

9 April 2020

Combined sublethal irradiation and agonist anti-CD40 enhance donor T cell accumulation and control of autochthonous murine pancreatic tumors (English)

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9 April 2020

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9 April 2020

Lindsay K Ward-Kavanagh

1

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9 April 2020

Kathleen M Kokolus

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9 April 2020

Aron E Lukacher

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9 April 2020

author name string

Timothy K Cooper

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9 April 2020

publication date

13 January 2018

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9 April 2020

Cancer Immunology, Immunotherapy

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9 April 2020

67

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9 April 2020

4

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9 April 2020

639-652

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9 April 2020

Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy

1 reference

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CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer

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Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8( ) T cells

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Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy

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A phase I study of an agonist CD40 monoclonal antibody (CP-870,893) in combination with gemcitabine in patients with advanced pancreatic ductal adenocarcinoma

1 reference

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Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells

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Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment

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Agonistic CD40 antibodies and cancer therapy

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T-helper-1-cell cytokines drive cancer into senescence

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Intratumoral peptide injection enhances tumor cell antigenicity recognized by cytotoxic T lymphocytes: a potential option for improvement in antigen-specific cancer immunotherapy

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PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines

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Augmented IL-15Rα expression by CD40 activation is critical in synergistic CD8 T cell-mediated antitumor activity of anti-CD40 antibody with IL-15 in TRAMP-C2 tumors in mice

1 reference

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Agonistic antibody to CD40 boosts the antitumor activity of adoptively transferred T cells in vivo

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Determinants of successful CD8 T-cell adoptive immunotherapy for large established tumors in mice

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Identification of quantitative trait loci for murine autoimmune pancreatitis.

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CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans

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Combined anti-CD40 conditioning and well-timed immunization prolongs CD8 T cell accumulation and control of established brain tumors

1 reference

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CD8 T cells targeting a single immunodominant epitope are sufficient for elimination of established SV40 T antigen-induced brain tumors.

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Anti-CD40 conditioning enhances the T(CD8) response to a highly tolerogenic epitope and subsequent immunotherapy of simian virus 40 T antigen-induced pancreatic tumors

1 reference

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Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8 T cells via TLR4 signaling.

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IFN-gamma regulates donor CD8 T cell expansion, migration, and leads to apoptosis of cells of a solid tumor.

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/29332158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early immunization induces persistent tumor-infiltrating CD8 T cells against an immunodominant epitope and promotes lifelong control of pancreatic tumor progression in SV40 tumor antigen transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29332158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiotherapy promotes tumor-specific effector CD8 T cells via dendritic cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29332158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00262-018-2115-2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29332158 AND SRC:MED&resulttype=core&format=json

9 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29332158 AND SRC:MED&resulttype=core&format=json

9 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29332158 AND SRC:MED&resulttype=core&format=json

9 April 2020

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