Blockade of TREM-2 exacerbates experimental autoimmune encephalomyelitis (Q48218333)

9 February 2018

title

Blockade of TREM-2 exacerbates experimental autoimmune encephalomyelitis (English)

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9 February 2018

experimental autoimmune encephalomyelitis

main subject

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author

Marco Colonna

7

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Laura Piccio

Laura Piccio

1

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Marina Cella

Marina Cella

4

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Anne H. Cross

Anne H Cross

6

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Paola Panina-Bordignon

8

Paola Panina-Bordignon

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9 February 2018

Cecilia Buonsanti

2

Cecilia Buonsanti

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9 February 2018

author name string

Margherita Mariani

3

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Susan Gilfillan

5

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language of work or name

English

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publication date

1 May 2007

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9 February 2018

European Journal of Immunology

published in

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9 February 2018

volume

37

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9 February 2018

issue

5

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9 February 2018

page(s)

1290-1301

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9 February 2018

Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.

cites work

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https://api.crossref.org/works/10.1002/EJI.200636837

Cutting Edge: TREM-2 Attenuates Macrophage Activation

21 January 2018

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https://api.crossref.org/works/10.1002/EJI.200636837

CNS manifestations of Nasu-Hakola disease: a frontal dementia with bone cysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

Pattern recognition by TREM-2: binding of anionic ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

https://api.crossref.org/works/10.1002/EJI.200636837

1 reference

7 January 2021

Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Immune function of microglia

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Microglia: a sensor for pathological events in the CNS

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Microglial response to brain injury: a brief synopsis

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Impaired differentiation of osteoclasts in TREM-2-deficient individuals

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

TREMs in the immune system and beyond

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts.

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2.

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Dap12 and Trem2, molecules involved in innate immunity and neurodegeneration, are co-expressed in the CNS.

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

DAP12-deficient mice fail to develop autoimmunity due to impaired antigen priming

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

KARAP/DAP12/TYROBP: three names and a multiplicity of biological functions

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Triggering receptor expressed in myeloid cells 2 (TREM2) trafficking in microglial cells: continuous shuttling to and from the plasma membrane regulated by cell stimulation.

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Brain microglia and blood-derived macrophages: molecular profiles and functional roles in multiple sclerosis and animal models of autoimmune demyelinating disease

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Microglia and multiple sclerosis

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Microglia induce myelin basic protein-specific T cell anergy or T cell activation, according to their state of activation

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Microglial cell activation and proliferation precedes the onset of CNS autoimmunity

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

The chemokine system in diverse forms of macrophage activation and polarization

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

The development of autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein is associated with an upregulation of both proinflammatory and immunoregulatory cytokines in the central nervous system

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

https://api.crossref.org/works/10.1002/EJI.200636837

1 reference

7 January 2021

The macrophage and the apoptotic cell: an innate immune interaction viewed simplistically?

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

"Eat me" and "don't eat me" signals govern the innate immune response and tissue repair in the CNS: emphasis on the critical role of the complement system

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Phagocytosis of apoptotic inflammatory cells by microglia and modulation by different cytokines: mechanism for removal of apoptotic cells in the inflamed nervous system

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Apoptosis of inflammatory cells in immune control of the nervous system: role of glia

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

LacZ inducible, antigen/MHC-specific T cell hybrids

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Plat-E: an efficient and stable system for transient packaging of retroviruses

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

A tumor necrosis factor receptor 1-dependent conversation between central nervous system-specific T cells and the central nervous system is required for inflammatory infiltration of the spinal cord.

1 reference

https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Parenchymal microglia of naïve adult C57BL/6J mice express high levels of B7.1, B7.2, and MHC class II

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https://api.crossref.org/works/10.1002/EJI.200636837

7 January 2021

Identifiers

DOI

10.1002/EJI.200636837

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9 February 2018

release_3z3hq6sd7fdpnlrstweu5dvjqi

Fatcat ID

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1 reference

9 February 2018