Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice (Q48194110)

9 February 2018

http://europepmc.org/abstract/MED/28238167

title

Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice (English)

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9 February 2018

http://europepmc.org/abstract/MED/28238167

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13 June 2020

author name string

Daniela Giuliani

2

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13 June 2020

Giovanni Pallio

3

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13 June 2020

Natasha Irrera

4

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13 June 2020

Eleonora Vandini

5

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13 June 2020

Fabrizio Canalini

6

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13 June 2020

Davide Zaffe

7

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13 June 2020

Alessandra Ottani

8

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13 June 2020

Letteria Minutoli

9

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13 June 2020

Mariagrazia Rinaldi

10

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13 June 2020

Salvatore Guarini

11

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13 June 2020

Francesco Squadrito

12

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13 June 2020

Domenica Altavilla

13

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13 June 2020

publication date

25 February 2017

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9 February 2018

http://europepmc.org/abstract/MED/28238167

published in

Inflammation Research

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13 June 2020

volume

66

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13 June 2020

issue

5

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13 June 2020

page(s)

389-398

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Immunotherapy against amyloid pathology in Alzheimer's disease

13 June 2020

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5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease

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Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model

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Mitochondrial ROS fuel the inflammasome

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Flavocoxid Inhibits Phospholipase A2, Peroxidase Moieties of the Cyclooxygenases (COX), and 5-Lipoxygenase, Modifies COX-2 Gene Expression, and Acts as an Antioxidant

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Flavocoxid, a nutraceutical approach to blunt inflammatory conditions.

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RETRACTED ARTICLE: Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis

21 January 2018

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A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation

21 January 2018

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A dual inhibitor of cyclooxygenase and 5-lipoxygenase protects against kainic acid-induced brain injury

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels

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21 January 2018

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Decrease of ERK/MAPK overactivation in prefrontal cortex reverses early memory deficit in a mouse model of Alzheimer's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28238167

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

From epidemiology to therapeutic trials with anti-inflammatory drugs in Alzheimer's disease: the role of NSAIDs and cyclooxygenase in beta-amyloidosis and clinical dementia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28238167

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00011-017-1022-X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28238167 AND SRC:MED&resulttype=core&format=json

13 June 2020

1 reference