mRNA 3'-UTR shortening is a molecular signature of mTORC1 activation (Q48173809)

9 February 2018

http://europepmc.org/abstract/MED/26074333

title

mRNA 3'-UTR shortening is a molecular signature of mTORC1 activation (English)

1 reference

9 February 2018

http://europepmc.org/abstract/MED/26074333

author

Ebbing P de Jong

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26074333 AND SRC:MED&resulttype=core&format=json

13 June 2020

Wei Zhang

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26074333 AND SRC:MED&resulttype=core&format=json

13 June 2020

Kenneth B Beckman

8

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13 June 2020

Timothy Griffin

12

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13 June 2020

author name string

Jae-Woong Chang

1

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13 June 2020

Hsin-Sung Yeh

3

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13 June 2020

Semo Jun

5

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13 June 2020

Kwan-Hyun Kim

6

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13 June 2020

Sun S Bae

7

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13 June 2020

Tae Hyun Hwang

9

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13 June 2020

Kye-Seong Kim

10

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13 June 2020

Rui Kuang

13

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13 June 2020

Jeongsik Yong

14

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13 June 2020

Do-Hyung Kim

11

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13 June 2020

language of work or name

English

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publication date

15 June 2015

1 reference

9 February 2018

http://europepmc.org/abstract/MED/26074333

published in

Nature Communications

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13 June 2020

volume

6

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13 June 2020

page(s)

7218

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Alternative cleavage and polyadenylation: extent, regulation and function

13 June 2020

cites work

1 reference

Alternative cleavage and polyadenylation: the long and short of it

21 January 2018

1 reference

Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors

21 January 2018

1 reference

Alternative polyadenylation: new insights from global analyses

21 January 2018

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Alternative mRNA polyadenylation in eukaryotes: an effective regulator of gene expression

21 January 2018

1 reference

Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites

21 January 2018

1 reference

Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells

21 January 2018

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Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq

21 January 2018

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Analysis of alternative cleavage and polyadenylation by 3' region extraction and deep sequencing.

21 January 2018

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Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

21 January 2018

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Alternative isoform regulation in human tissue transcriptomes

21 January 2018

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Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

21 January 2018

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Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development.

21 January 2018

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Global changes in processing of mRNA 3' untranslated regions characterize clinically distinct cancer subtypes

21 January 2018

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mTOR signaling in growth control and disease

21 January 2018

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Molecular mechanisms of mTOR-mediated translational control

21 January 2018

1 reference

The translational landscape of mTOR signalling steers cancer initiation and metastasis

21 January 2018

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A unifying model for mTORC1-mediated regulation of mRNA translation.

21 January 2018

1 reference

Regulation of mTORC1 and its impact on gene expression at a glance

21 January 2018

1 reference

A Central role for mTOR in lipid homeostasis

21 January 2018

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Coordinated regulation of protein synthesis and degradation by mTORC1

21 January 2018

1 reference

A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells

21 January 2018

1 reference

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

21 January 2018

1 reference

TSC1 involvement in bladder cancer: diverse effects and therapeutic implications

21 January 2018

1 reference

Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy

21 January 2018

1 reference

The pharmacology of mTOR inhibition

21 January 2018

1 reference

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

21 January 2018

1 reference

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

21 January 2018

1 reference

mTOR Kinase Domain Phosphorylation Promotes mTORC1 Signaling, Cell Growth, and Cell Cycle Progression

21 January 2018

1 reference

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

21 January 2018

1 reference

Making new contacts: the mTOR network in metabolism and signalling crosstalk

21 January 2018

1 reference

A growing role for mTOR in promoting anabolic metabolism

21 January 2018

1 reference

TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation.

21 January 2018

1 reference

Ubiquitin ligases and cell cycle control

21 January 2018

1 reference

Translational homeostasis via the mRNA cap-binding protein, eIF4E

21 January 2018

1 reference

Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses

21 January 2018

1 reference

Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.

21 January 2018

1 reference

The role of RING box protein 1 in mouse oocyte meiotic maturation

21 January 2018

1 reference

Mitotic regulation of the human anaphase-promoting complex by phosphorylation

21 January 2018

1 reference

RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival

21 January 2018

1 reference

Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase

21 January 2018

1 reference

TopHat: discovering splice junctions with RNA-Seq

21 January 2018

1 reference

Patterns of variant polyadenylation signal usage in human genes

21 January 2018

1 reference

A large-scale analysis of mRNA polyadenylation of human and mouse genes

21 January 2018

1 reference

Universal sample preparation method for proteome analysis

21 January 2018

1 reference

Reversed-phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells

21 January 2018

1 reference

Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling.

21 January 2018

1 reference

Mutation spectrum of the 9q34 tuberous sclerosis gene TSC1 in transitional cell carcinoma of the bladder.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26074333