Conformational stability of the epidermal growth factor (EGF) receptor as influenced by glycosylation, dimerization and EGF hormone binding. (Q48117891)

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3 April 2020

title

Conformational stability of the epidermal growth factor (EGF) receptor as influenced by glycosylation, dimerization and EGF hormone binding (English)

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3 April 2020

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2

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3 April 2020

author name string

Eric S Taylor

series ordinal

1

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3 April 2020

Roberto D Lins

series ordinal

3

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3 April 2020

Steven K Lower

series ordinal

4

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3 April 2020

language of work or name

English

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publication date

18 January 2017

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3 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28019699 AND SRC:MED&resulttype=core&format=json

3 April 2020

volume

85

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3 April 2020

issue

4

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3 April 2020

page(s)

561-570

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The Inflammasome and the Epidermal Growth Factor Receptor (EGFR) Are Involved in the Staphylococcus aureus-Mediated Induction of IL-1alpha and IL-1beta in Human Keratinocytes

3 April 2020

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Cell Signaling in Mesothelial Cells by Asbestos: Evidence for the Involvement of Oxidative Stress in the Regulation of the Epidermal Growth Factor Receptor

16 June 2018

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N-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes

16 June 2018

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Effects of N-glycosylation on protein conformation and dynamics: Protein Data Bank analysis and molecular dynamics simulation study.

16 June 2018

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Membrane interaction of bound ligands contributes to the negative binding cooperativity of the EGF receptor

16 June 2018

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The EGFR family: not so prototypical receptor tyrosine kinases

16 June 2018

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Repetitive dissociation from crocidolite asbestos acts as persistent signal for epidermal growth factor receptor

16 June 2018

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Molecular determinants of epidermal growth factor binding: a molecular dynamics study

16 June 2018

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Architecture and membrane interactions of the EGF receptor

16 June 2018

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Conformational coupling across the plasma membrane in activation of the EGF receptor

16 June 2018

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Staphylococcus aureus protein A mediates invasion across airway epithelial cells through activation of RhoA GTPase signaling and proteolytic activity.

16 June 2018

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The core trisaccharide of an N-linked glycoprotein intrinsically accelerates folding and enhances stability

16 June 2018

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Ligand-induced ErbB receptor dimerization

16 June 2018

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Interaction of antibodies with ErbB receptor extracellular regions

16 June 2018

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N-Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor

16 June 2018

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EGFR antagonists in cancer treatment

16 June 2018

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Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation.

16 June 2018

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Staphylococcus aureus protein A activates TACE through EGFR-dependent signaling

16 June 2018

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Functional effects of glycosylation at Asn-579 of the epidermal growth factor receptor

16 June 2018

1 reference

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Validation of the 53A6 GROMOS force field

16 June 2018

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Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

16 June 2018

1 reference

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Real-time kinetics of ligand/cell surface receptor interactions in living cells: binding of epidermal growth factor to the epidermal growth factor receptor

16 June 2018

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Epidermal growth factor receptor glycosylation is required for ganglioside GM3 binding and GM3-mediated suppression [correction of suppresion] of activation

16 June 2018

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Glycosylation-induced conformational modification positively regulates receptor-receptor association: a study with an aberrant epidermal growth factor receptor (EGFRvIII/DeltaEGFR) expressed in cancer cells

16 June 2018

1 reference

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Analysis of the glycosylation patterns of the extracellular domain of the epidermal growth factor receptor expressed in Chinese hamster ovary fibroblasts

16 June 2018

1 reference

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How MAP kinases are regulated

16 June 2018

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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

16 June 2018

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Glycosylation of the epidermal growth factor receptor in A-431 cells. The contribution of carbohydrate to receptor function

16 June 2018

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Synthesis of epidermal growth factor receptor in human A431 cells. Glycosylation-dependent acquisition of ligand binding activity occurs post-translationally in the endoplasmic reticulum.

16 June 2018

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Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor

16 June 2018

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Ectodomain orientation, conformational plasticity and oligomerization of ErbB1 receptors investigated by molecular dynamics.

16 June 2018

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N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion.

14 August 2018

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A new GROMOS force field for hexopyranose-based carbohydrates

14 August 2018

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Overexpression of N-acetylglucosaminyltransferase III enhances the epidermal growth factor-induced phosphorylation of ERK in HeLaS3 cells by up-regulation of the internalization rate of the receptors.

14 August 2018

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The missing term in effective pair potentials

14 August 2018

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Crossref

https://api.crossref.org/works/10.1002/PROT.25220

Molecular dynamics with coupling to an external bath

21 January 2018

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Crossref

https://api.crossref.org/works/10.1002/PROT.25220

The Asn418-linked N-glycan of ErbB3 plays a crucial role in preventing spontaneous heterodimerization and tumor promotion

21 January 2018

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12 December 2020

The Asn-420-linked sugar chain in human epidermal growth factor receptor suppresses ligand-independent spontaneous oligomerization. Possible role of a specific sugar chain in controllable receptor activation

1 reference

12 December 2020

Fucosylated hybrid-type N-glycans on the secreted human epidermal growth factor receptor from swainsonine-treated A431 cells

1 reference

12 December 2020

Increased expression of epidermal growth factor receptor in rat pleural mesothelial cells correlates with carcinogenicity of mineral fibres

1 reference

12 December 2020

Extension and validation of the GROMOS 53A6(GLYC) parameter set for glycoproteins

1 reference

12 December 2020

Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor

1 reference

12 December 2020

Identifiers

DOI

10.1002/PROT.25220

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28019699 AND SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28019699 AND SRC:MED&resulttype=core&format=json

3 April 2020

PubMed publication ID

28019699

1 reference