Hot melt extruded Aprepitant-Soluplus solid dispersion: preformulation considerations, stability and in vitro study (Q48062570)

8 February 2018

title

Hot melt extruded Aprepitant-Soluplus solid dispersion: preformulation considerations, stability and in vitro study (English)

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8 February 2018

author name string

Sai Sumana Penumetcha

1

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Lakshmi Narayana Gutta

2

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Harish Dhanala

3

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Satyanarayana Yamili

4

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Swetha Challa

5

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Sneha Rudraraju

6

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Soumya Rudraraju

7

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Varma Rudraraju

8

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language of work or name

English

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publication date

1 March 2016

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Drug Development and Industrial Pharmacy

published in

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volume

42

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issue

10

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page(s)

1609-1620

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Melt extrusion with poorly soluble drugs

cites work

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Klucel™ EF and ELF polymers for immediate-release oral dosage forms prepared by melt extrusion technology

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Characterisation of solid dispersions of paracetamol and EUDRAGIT E prepared by hot-melt extrusion using thermal, microthermal and spectroscopic analysis.

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Physicochemical characterization of felodipine-kollidon VA64 amorphous solid dispersions prepared by hot-melt extrusion

21 January 2018

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Physicochemical characterization of hot melt extruded bicalutamide-polyvinylpyrrolidone solid dispersions

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Water vapor sorption of hot-melt extruded hydroxypropyl cellulose films: effect on physico-mechanical properties, release characteristics, and stability

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In vitro and in vivo evaluation of amorphous solid dispersions generated by different bench-scale processes, using griseofulvin as a model compound

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The use of three different solid dispersion formulations--melt extrusion, film-coated beads, and a glass thermoplastic system--to improve the bioavailability of a novel microsomal triglyceride transfer protein inhibitor

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A solid-state approach to enable early development compounds: selection and animal bioavailability studies of an itraconazole amorphous solid dispersion

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A classification system to assess the crystallization tendency of organic molecules from undercooled melts.

21 January 2018

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Selection of excipients for melt extrusion with two poorly water-soluble drugs by solubility parameter calculation and thermal analysis.

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Theoretical and practical approaches for prediction of drug-polymer miscibility and solubility.

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Preparation and pharmacokinetic study of aprepitant-sulfobutyl ether-β-cyclodextrin complex

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Nanomedicines in the treatment of emesis during chemotherapy: focus on aprepitant

21 January 2018

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Preparation of carbamazepine-Soluplus solid dispersions by hot-melt extrusion, and prediction of drug-polymer miscibility by thermodynamic model fitting

21 January 2018

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Characterization and quantitation of aprepitant drug substance polymorphs by attenuated total reflectance fourier transform infrared spectroscopy

21 January 2018

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Rate-limiting steps of oral absorption for poorly water-soluble drugs in dogs; prediction from a miniscale dissolution test and a physiologically-based computer simulation.

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Characterization and performance assessment of solid dispersions prepared by hot melt extrusion and spray drying process

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21 January 2018

Identifiers

DOI

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8 February 2018

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8 February 2018