Cell Death Mechanisms of Neurodegeneration (Q47961296)

7 February 2018

review article

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title

Cell Death Mechanisms of Neurodegeneration (English)

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7 February 2018

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2

Ted M Dawson

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7 February 2018

Jing Fan

1

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7 February 2018

Valina L Dawson

series ordinal

3

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7 February 2018

publication date

1 January 2017

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7 February 2018

published in

Advances in neurobiology

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7 February 2018

volume

15

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7 February 2018

page(s)

403-425

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7 February 2018

Cell death in the nervous system

cites work

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis in neural development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Necroptosis drives motor neuron death in models of both sporadic and familial ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Activation of necroptosis in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Compromised autophagy and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The role of autophagy in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Control of autophagy as a therapy for neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Parthanatos, a messenger of death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Mitochondrial and nuclear cross talk in cell death: parthanatos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Excitotoxicity: bridge to various triggers in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Excitotoxic and Excitoprotective Mechanisms: Abundant Targets for the Prevention and Treatment of Neurodegenerative Disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) (PAR) polymer is a death signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The roles of PARP1 in gene control and cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

21 January 2018

PARP goes transcription

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose): novel functions for an old molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribosyl)ated chromatin domains: access granted

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribosyl)ation by PARP-1: 'PAR-laying' NAD into a nuclear signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribosyl)ation regulation of life and death in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) glycohydrolase silencing protects against H2O2-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis-inducing factor: a matter of neuron life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis-inducing factor: vital and lethal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Role of AIF in caspase-dependent and caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1–Dependent Cell Death (Parthanatos)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Deadly conversations: nuclear-mitochondrial cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The selective poly(ADP)ribose-polymerase 1 inhibitor INO1001 reduces spinal cord injury during porcine aortic cross-clamping-induced ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Aβ(1-42)-induced rat model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

PARP-1 modulates amyloid beta peptide-induced neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

(ADP-ribose) polymerase 1 and AMP-activated protein kinase mediate progressive dopaminergic neuronal degeneration in a mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Pharmacological inhibition of PARP-1 reduces alpha-synuclein- and MPP -induced cytotoxicity in Parkinson's disease in vitro models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Expression pattern of apoptosis-related markers in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) polymerase-1 activation in a primate model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

PARP expression is increased in astrocytes but decreased in motor neurons in the spinal cord of sporadic ALS patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

PARP-1 involvement in neurodegeneration: A focus on Alzheimer's and Parkinson's diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly (ADP-ribose) polymerase, nitric oxide and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Therapeutic effect of a novel anti-parkinsonian agent zonisamide against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Molecular pathophysiology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Amyloid Precursor Protein Processing and Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Clinical perspectives of PARP inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Compensatory caspase activation in MPP -induced cell death in dopaminergic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis inducing factor mediates caspase-independent 1-methyl-4-phenylpyridinium toxicity in dopaminergic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis-inducing factor mediates dopaminergic cell death in response to LPS-induced inflammatory stimulus: evidence in Parkinson's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

AIF translocates to the nucleus in the spinal motor neurons in a mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Apoptosis-Inducing Factor Deficiency Induces Early Mitochondrial Degeneration in Brain Followed by Progressive Multifocal Neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The harlequin mouse mutation downregulates apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Therapeutic potential of AIF-mediated caspase-independent programmed cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Transient Poly(ADP-ribosyl)ation of Nuclear Proteins and Role of Poly(ADP-ribose) Polymerase in the Early Stages of Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribose) signaling in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Targeting programmed cell death in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

21 January 2018

Memantine hydrochloride.

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Poly(ADP-ribosylation) and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

Excessive Activation of Poly(ADP-Ribose) Polymerase Contributes to Inherited Photoreceptor Degeneration in the Retinal Degeneration 1 Mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-57193-5_16

10.1007/978-3-319-57193-5_16

21 January 2018

Identifiers

DOI

1 reference

7 February 2018

1 reference

7 February 2018