Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma (Q47925032)

6 February 2018

title

Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma (English)

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7

Youssef Daali

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author name string

Marija Bosilkovska

1

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Julien Déglon

2

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Caroline Samer

3

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Bernhard Walder

4

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Jules Desmeules

5

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Christian Staub

6

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publication date

1 January 2014

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6 February 2018

published in

Bioanalysis

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volume

6

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issue

2

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page(s)

151-164

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Appropriate phenotyping procedures for drug metabolizing enzymes and transporters in humans and their simultaneous use in the "cocktail" approach

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Evaluation of flurbiprofen urinary ratios as in vivo indices for CYP2C9 activity.

21 January 2018

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Development of the "Inje cocktail" for high-throughput evaluation of five human cytochrome P450 isoforms in vivo

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Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers

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21 January 2018

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Application of dried blood spots combined with HPLC-MS/MS for the quantification of acetaminophen in toxicokinetic studies.

21 January 2018

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Therapeutic drug monitoring of antiretroviral drugs at home using dried blood spots: a proof-of-concept study

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Dried blood spot analysis for therapeutic drug monitoring of linezolid in patients with multidrug-resistant tuberculosis

21 January 2018

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Clinical validation of dried blood spot sampling in therapeutic drug monitoring of ciclosporin A in allogeneic stem cell transplant recipients: direct comparison between capillary and venous sampling

21 January 2018

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Application of dried blood spot sampling combined with LC-MS/MS for genotyping and phenotyping of CYP450 enzymes in healthy volunteers

21 January 2018

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Validation of Individual Quantitative Methods for Determination of Cytochrome P450 Probe Substrates in Human Dried Blood Spots with HPLC–MS/MS

21 January 2018

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Rapid LC-MS/MS quantification of the major benzodiazepines and their metabolites on dried blood spots using a simple and cost-effective sample pretreatment.

21 January 2018

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Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5 1 cocktail".

21 January 2018

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21 January 2018

Identifiers

DOI

10.4155/BIO.13.289

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6 February 2018

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6 February 2018