Purinergic dysregulation causes hypertensive glaucoma-like optic neuropathy (Q47863338)

15 June 2018

title

Purinergic dysregulation causes hypertensive glaucoma-like optic neuropathy (English)

1 reference

15 June 2018

Youichi Shinozaki

1

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author name string

Kenji Kashiwagi

2

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15 June 2018

Kazuhiko Namekata

3

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15 June 2018

Akiko Takeda

4

1 reference

15 June 2018

Nobuhiko Ohno

5

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15 June 2018

Bernard Robaye

6

1 reference

15 June 2018

Takayuki Harada

7

1 reference

15 June 2018

Takeshi Iwata

8

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15 June 2018

Schuichi Koizumi

9

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15 June 2018

publication date

5 October 2017

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15 June 2018

published in

JCI insight

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15 June 2018

volume

2

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15 June 2018

issue

19

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15 June 2018

Diadenosine tetraphosphate as a potential therapeutic nucleotide to treat glaucoma.

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Mechanosensitive release of adenosine 5'-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: a mechanism for purinergic involvement in chronic strain

16 June 2018

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16 June 2018

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16 June 2018

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Relationship of central corneal thickness and intraocular pressure by iCare rebound tonometer

16 June 2018

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Retinal ganglion cell and inner plexiform layer thickness measurements in regions of severe visual field sensitivity loss in patients with glaucoma

16 June 2018

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Retinal ganglion cell layer thickness and local visual field sensitivity in glaucoma.

16 June 2018

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Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucoma

16 June 2018

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Early microglia activation in a mouse model of chronic glaucoma

16 June 2018

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Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow

16 June 2018

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2-MeS-beta,gamma-CCl2-ATP is a potent agent for reducing intraocular pressure

16 June 2018

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Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of AA in trabecular meshwork cells

16 June 2018

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Measurement of local retinal ganglion cell layer thickness in patients with glaucoma using frequency-domain optical coherence tomography

16 June 2018

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P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

16 June 2018

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Elevated pressure triggers a physiological release of ATP from the retina: Possible role for pannexin hemichannels.

16 June 2018

1 reference

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Immunolocalisation of P2Y receptors in the rat eye.

16 June 2018

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UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

16 June 2018

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The influence of central corneal thickness and age on intraocular pressure measured by pneumotonometry, non-contact tonometry, the Tono-Pen XL, and Goldmann applanation tonometry

16 June 2018

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The effect of corneal thickness on intraocular pressure measurement in patients with corneal pathology

16 June 2018

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Basis of chloride transport in ciliary epithelium

16 June 2018

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The ins and outs of aqueous humour secretion

16 June 2018

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Stress-induced ATP release from and growth modulation of human lens and retinal pigment epithelial cells

16 June 2018

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Attenuation of signal flow from P2Y6 receptor by protein kinase C‐α in SK‐N‐BE(2)C human neuroblastoma cells

16 June 2018

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Glial cell inhibition of neurons by release of ATP

16 June 2018

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P2Y6 receptor mediates colonic NaCl secretion via differential activation of cAMP-mediated transport

16 June 2018

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Noninvasive assessment of aqueous humor turnover in the mouse eye.

16 June 2018

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Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial

16 June 2018

1 reference

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Propagation of intercellular calcium waves in retinal astrocytes and Müller cells

16 June 2018

1 reference

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The role of NaKCl cotransport in blood-to-aqueous chloride fluxes across rabbit ciliary epithelium.

16 June 2018

1 reference

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Age-associated increase in PGE2 synthesis and COX activity in murine macrophages is reversed by vitamin E

16 June 2018

1 reference

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A release mechanism for stored ATP in ocular ciliary epithelial cells

16 June 2018

1 reference

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Age-dependent increases in protein kinase C-alpha beta immunoreactivity and activity in the human brain: possible in vivo modulatory effects on guanine nucleotide regulatory G(i) proteins

16 June 2018

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Number of people with glaucoma worldwide

16 June 2018

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Pathways signaling the regulatory volume decrease of cultured nonpigmented ciliary epithelial cells.

16 June 2018

1 reference

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Role of cyclic AMP-induced Cl conductance in aqueous humour formation by the dog ciliary epithelium

16 June 2018

1 reference

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The prevalence of primary open-angle glaucoma in a population-based study in The Netherlands. The Rotterdam Study.

16 June 2018

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Risk factors for open-angle glaucoma. The Barbados Eye Study

16 June 2018

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The potential role of Ca2 for electrical cell-to-cell uncoupling and conduction block in myocardial tissue

16 June 2018

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Timolol inhibition of aqueous humor production in the cat

16 June 2018

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Permeability of cell junction depends on local cytoplasmic calcium activity

16 June 2018

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Silencing of P2Y2 receptors reduces intraocular pressure in New Zealand rabbits

16 June 2018

1 reference

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Hyposmotic stress causes ATP release and stimulates Na,K-ATPase activity in porcine lens

14 August 2018

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14 August 2018

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Inhibitions of chloride transport and gap junction reduce fluid flow across the whole porcine ciliary epithelium.

14 August 2018

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Knockout mice reveal a role for P2Y6 receptor in macrophages, endothelial cells, and vascular smooth muscle cells

14 August 2018

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Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma

14 August 2018

1 reference

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Hypotensive effect of UDP on intraocular pressure in rabbits.

14 August 2018

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The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma

14 August 2018

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Effects of central corneal thickness and corneal curvature on the intraocular pressure measurement by Goldmann applanation tonometer and ocular blood flow pneumatonometer.

14 August 2018

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Effects of dinucleoside polyphosphates on trabecular meshwork cells and aqueous humor outflow facility.

14 August 2018

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ATP release through connexin hemichannels in corneal endothelial cells

14 August 2018

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cAMP inhibits transepithelial chloride secretion across bovine ciliary body/epithelium

14 August 2018

1 reference

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Adenosine Tetraphosphate, Ap4, a Physiological Regulator of Intraocular Pressure in Normotensive Rabbit Eyes

14 August 2018

1 reference

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Common actions of adenosine receptor agonists in modulating human trabecular meshwork cell transport

14 August 2018

1 reference

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Presence of diadenosine polyphosphates in the aqueous humor: their effect on intraocular pressure

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5841869

TGF-beta effects on epithelial ion transport and barrier: reduced Cl- secretion blocked by a p38 MAPK inhibitor

14 August 2018

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The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.

14 August 2018

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Timolol may inhibit aqueous humor secretion by cAMP-independent action on ciliary epithelial cells

14 August 2018

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Model of ionic transport for bovine ciliary epithelium: effects of acetazolamide and HCO.

14 August 2018

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Chloride secretion by bovine ciliary epithelium: a model of aqueous humor formation.

14 August 2018

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The prevalence of glaucoma in the Melbourne Visual Impairment Project

14 August 2018

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Pharmacological and second messenger signalling selectivities of cloned P2Y receptors.

14 August 2018

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Müller cell-mediated neurite outgrowth of the retinal ganglion cells via P2Y6 receptor signals

14 August 2018

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12 December 2020

Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors

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12 December 2020

The optic nerve head component of the human ERG

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12 December 2020

Action Mechanism of Timolol to Lower the Intraocular Pressure in Rabbits

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12 December 2020

Forskolin lowers intraocular pressure in rabbits, monkeys, and man

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12 December 2020

Sodium and chloride transport across the isolated rabbit ciliary body

1 reference

12 December 2020

The influence of central corneal thickness and corneal curvature radius on the intraocular pressure as measured by different tonometers: noncontact and goldmann applanation tonometers

1 reference

12 December 2020

Chloride and sodium transport across bovine ciliary body/epithelium (CBE)

1 reference

12 December 2020

Activated microglia in the human glaucomatous optic nerve head

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12 December 2020

Extracellular ATP: a growth factor for vascular smooth muscle cells

1 reference

12 December 2020

Junctional membrane permeability : Effects of divalent cations

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12 December 2020

Effect of topically applied forskolin on aqueous humor dynamics in cynomolgus monkey

1 reference

12 December 2020

Effect of corneal thickness on intraocular pressure measurements with the pneumotonometer, Goldmann applanation tonometer, and Tono-Pen

1 reference

12 December 2020

Acute increase of intraocular pressure releases ATP into the anterior chamber

1 reference

12 December 2020

Varying effects of corneal thickness on intraocular pressure measurements with different tonometers

1 reference

12 December 2020

Fluorophotometric study of epinephrine and timolol in human subjects

1 reference

12 December 2020

Glaucoma patients present increased levels of diadenosine tetraphosphate, Ap(4)A, in the aqueous humour

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12 December 2020

Risk factors for open-angle glaucoma in a Japanese population: the Tajimi Study

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12 December 2020

Effects of corneal thickness on intraocular pressure measured with three different tonometers

1 reference

12 December 2020

10.1172/JCI.INSIGHT.93456

Identifiers

DOI

1 reference

15 June 2018

PMC publication ID

5841869

1 reference

15 June 2018

PubMed publication ID

28978804

1 reference

15 June 2018