Farnesyltransferase inhibitors versus Ras inhibitors. (Q47830137)

6 February 2018

review article

1 reference

title

Farnesyltransferase inhibitors versus Ras inhibitors. (English)

1 reference

6 February 2018

author name string

Gibbs JB

1

1 reference

6 February 2018

Graham SL

2

1 reference

6 February 2018

Hartman GD

3

1 reference

6 February 2018

Koblan KS

4

1 reference

6 February 2018

Kohl NE

5

1 reference

6 February 2018

Omer CA

6

1 reference

6 February 2018

Oliff A

7

1 reference

6 February 2018

publication date

1 August 1997

1 reference

6 February 2018

Current Opinion in Chemical Biology

published in

1 reference

6 February 2018

volume

1

1 reference

6 February 2018

issue

2

1 reference

6 February 2018

page(s)

197-203

1 reference

6 February 2018

Function and regulation of ras.

cites work

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Farnesyl transferase inhibitors: the successes and surprises of a new class of potential cancer chemotherapeutics

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

The potential of farnesyltransferase inhibitors as cancer chemotherapeutics

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Protein prenyltransferases

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Modulation of Ras and a-factor function by carboxyl-terminal proteolysis

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Protein isoprenylation and methylation at carboxyl-terminal cysteine residues

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Palmitoylation of Ha-Ras facilitates membrane binding, activation of downstream effectors, and meiotic maturation in Xenopus oocytes

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Suppression of human pancreatic cancer growth in BALB/c nude mice by manumycin, a farnesyl:protein transferase inhibitor

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Characterization of Ha-ras, N-ras, Ki-Ras4A, and Ki-Ras4B as in vitro substrates for farnesyl protein transferase and geranylgeranyl protein transferase type I

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Disruption of Oncogenic K-Ras4B Processing and Signaling by a Potent Geranylgeranyltransferase I Inhibitor

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro.

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Direct demonstration of geranylgeranylation and farnesylation of Ki-Ras in vivo

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

2-substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Design and synthesis of non-peptide Ras CAAX mimetics as potent farnesyltransferase inhibitors

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Discovery of novel nonpeptide tricyclic inhibitors of Ras farnesyl protein transferase

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Potent, cell active, non-thiol tetrapeptide inhibitors of farnesyltransferase.

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Structure-activity relationships of cysteine-lacking pentapeptide derivatives that inhibit ras farnesyltransferase

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Selection of potent inhibitors of farnesyl-protein transferase from a synthetic tetrapeptide combinatorial library

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Evidence for a catalytic role of zinc in protein farnesyltransferase. Spectroscopy of Co2 -farnesyltransferase indicates metal coordination of the substrate thiolate

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Substitution of cadmium for zinc in farnesyl:protein transferase alters its substrate specificity

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Amino acid substitutions that convert the protein substrate specificity of farnesyltransferase to that of geranylgeranyltransferase type I.

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Interaction of the transforming growth factor-beta type I receptor with farnesyl-protein transferase-alpha

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Interaction of transforming growth factor-beta receptor I with farnesyl-protein transferase-alpha in yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Effect of insulin on farnesyltransferase activity in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Ras oncoprotein inhibitors: the discovery of potent, ras nucleotide exchange inhibitors and the structural determination of a drug-protein complex

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase

1 reference

https://api.crossref.org/works/10.1016/S1367-5931(97)80010-5

7 January 2021

10.1016/S1367-5931(97)80010-5

Identifiers

DOI

1 reference

6 February 2018

1 reference

6 February 2018