Rasagiline delays retinal degeneration in a mouse model of retinitis pigmentosa via modulation of Bax/Bcl-2 expression. (Q47710236)

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13 March 2020

title

Rasagiline delays retinal degeneration in a mouse model of retinitis pigmentosa via modulation of Bax/Bcl-2 expression (English)

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13 March 2020

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Francisco J Diaz-Corrales

4

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13 March 2020

Sofia M Calado

3

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13 March 2020

author name string

Ana B Garcia-Delgado

1

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13 March 2020

Lourdes Valdés-Sánchez

2

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13 March 2020

Shom S Bhattacharya

5

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13 March 2020

publication date

25 January 2018

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CNS Neuroscience & Therapeutics

13 March 2020

published in

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volume

24

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issue

5

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page(s)

448-455

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describes a project that uses

13 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6489995/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Mutations in the PDE6B gene in autosomal recessive retinitis pigmentosa

1 reference

12 December 2020

Sparing by Rasagiline (Tvp-1012) of Cholinergic Functions and Behavior in the Postnatal Anoxia Rat

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12 December 2020

Rasagiline [N-propargyl-1R( )-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B

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12 December 2020

Neuroprotective effects of novel cholinesterase inhibitors derived from rasagiline as potential anti-Alzheimer drugs

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12 December 2020

Retinal degeneration mutants in the mouse

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12 December 2020

An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic bcl-2 in human dopaminergic SH-SY5Y cells

1 reference

12 December 2020

N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor

1 reference

12 December 2020

Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members

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12 December 2020

Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration

1 reference

12 December 2020

Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives

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12 December 2020

Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine

1 reference

12 December 2020

Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: interaction of Bcl-2 family members with PKC pathway

1 reference

12 December 2020

Biological characterization of gene response in Rpe65-/- mouse model of Leber's congenital amaurosis during progression of the disease

1 reference

12 December 2020

Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene

1 reference

12 December 2020

The BCL-2 protein family: opposing activities that mediate cell death

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12 December 2020

Mechanisms of apoptosis in retinitis pigmentosa.

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12 December 2020

Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease

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12 December 2020

The molecular basis of human retinal and vitreoretinal diseases

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12 December 2020

Rasagiline-induced delay of retinal ganglion cell death in experimental glaucoma in rats

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12 December 2020

Rasagiline interferes with neurodegeneration in the Prph2/rds mouse

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12 December 2020

ATR localizes to the photoreceptor connecting cilium and deficiency leads to severe photoreceptor degeneration in mice.

1 reference

12 December 2020

Rasagiline prevents neurodegeneration in thiamine deficient rats-a longitudinal MRI study

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12 December 2020

Retinal structure and function preservation by polysaccharides of wolfberry in a mouse model of retinal degeneration.

1 reference

12 December 2020

Rasagiline and selegiline suppress calcium efflux from mitochondria by PK11195-induced opening of mitochondrial permeability transition pore: a novel anti-apoptotic function for neuroprotection

1 reference

12 December 2020

BAX and BCL-2 polymorphisms, as predictors of proliferative vitreoretinopathy development in patients suffering retinal detachment: the Retina 4 project

1 reference

12 December 2020

Beneficial behavioral, neurochemical and molecular effects of 1-(R)-aminoindan in aged mice

1 reference

12 December 2020

Effect of long-term treatment with rasagiline on cognitive deficits and related molecular cascades in aged mice

1 reference

12 December 2020

Involvement of Bcl-2-associated athanogene (BAG)-family proteins in the neuroprotection by rasagiline

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12 December 2020

Identifiers

DOI

10.1111/CNS.12805

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29372592 AND SRC:MED&resulttype=core&format=json

13 March 2020

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13 March 2020

PubMed publication ID

29372592

1 reference