Expression of CCR7 in multiple sclerosis: implications for CNS immunity (Q47661247)

4 February 2018

title

Expression of CCR7 in multiple sclerosis: implications for CNS immunity (English)

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10

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Richard M Ransohoff

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object named as

Richard M Ransohoff

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author name string

Pia Kivisäkk

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Don J Mahad

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Melissa K Callahan

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Keith Sikora

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Corinna Trebst

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Barbara Tucky

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Jerome Wujek

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Rivka Ravid

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Susan M Staugaitis

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publication date

1 May 2004

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published in

Annals of Neurology

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volume

55

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issue

5

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page(s)

627-638

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T-Cell Function and Migration — Two Sides of the Same Coin

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CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

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Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses

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Three or more routes for leukocyte migration into the central nervous system

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Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephal

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Differential expression of CCL19 by DC-Lamp mature dendritic cells in human lymph node versus chronically inflamed skin

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EBI1-ligand chemokine (ELC) attracts a broad spectrum of lymphocytes: activated T cells strongly up-regulate CCR7 and efficiently migrate toward ELC.

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Identifiers

DOI

10.1002/ANA.20049

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4 February 2018

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