Chronic Administration of the N-Methyl-D-Aspartate Receptor Antagonist Ketamine Improves Rett Syndrome Phenotype (Q47647748)

4 February 2018

title

Chronic Administration of the N-Methyl-D-Aspartate Receptor Antagonist Ketamine Improves Rett Syndrome Phenotype (English)

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4 February 2018

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Annarita Patrizi

1

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4 February 2018

Nathalie Picard

2

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4 February 2018

Alex Joseph Simon

3

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4 February 2018

Georgia Gunner

4

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4 February 2018

Eleonora Centofante

5

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4 February 2018

Nick Arthur Andrews

6

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4 February 2018

Michela Fagiolini

7

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4 February 2018

language of work or name

English

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publication date

24 August 2015

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4 February 2018

published in

Biological Psychiatry

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4 February 2018

volume

79

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4 February 2018

issue

9

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4 February 2018

page(s)

755-764

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4 February 2018

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.

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The MeCP2-null mouse hippocampus displays altered basal inhibitory rhythms and is prone to hyperexcitability.

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Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment

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12 December 2020

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BDNF deregulation in Rett syndrome

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10.1016/J.BIOPSYCH.2015.08.018

Identifiers

DOI

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4 February 2018

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4 February 2018