TIEG and estrogen modulate SOST expression in the murine skeleton. (Q47606161)

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7 April 2020

title

TIEG and estrogen modulate SOST expression in the murine skeleton (English)

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7 April 2020

5

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7 April 2020

author name string

Malayannan Subramaniam

1

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7 April 2020

Kevin S Pitel

2

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7 April 2020

Elizabeth S Bruinsma

3

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7 April 2020

David G Monroe

4

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7 April 2020

publication date

24 November 2017

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Journal of Cellular Physiology

7 April 2020

published in

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volume

233

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issue

4

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7 April 2020

page(s)

3540-3551

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Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

7 April 2020

cites work

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Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein

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TIEG1/KLF10 modulates Runx2 expression and activity in osteoblasts

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TIEG-null mice display an osteopenic gender-specific phenotype

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TGFβ inducible early gene-1 plays an important role in mediating estrogen signaling in the skeleton

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Estrogen-TGFbeta cross-talk in bone and other cell types: role of TIEG, Runx2, and other transcription factors

21 January 2018

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Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: an essential role for the activation function 1 domain

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Overexpression of a nuclear protein, TIEG, mimics transforming growth factor-beta action in human osteoblast cells

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TGFbeta inducible early gene-1 directly binds to, and represses, the OPG promoter in osteoblasts

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TIEG1 enhances Osterix expression and mediates its induction by TGFβ and BMP2 in osteoblasts

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PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5741473

Crosstalk between Wnt and bone morphogenic protein signaling: a turbulent relationship

2 November 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5741473

Cytokine-specific induction of the TGF-beta inducible early gene (TIEG): regulation by specific members of the TGF-beta family

2 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29044507

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/JCP.26211

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release_5wxnyfv6ung2ni6g67uoxli3ga

7 April 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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7 April 2020

PubMed publication ID

29044507

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