Low FoxG1 and high Olig-2 labelling indices define a prognostically favourable subset in isocitrate dehydrogenase (IDH)-mutant gliomas. (Q47592896)

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7 April 2020

title

Low FoxG1 and high Olig-2 labelling indices define a prognostically favourable subset in isocitrate dehydrogenase (IDH)-mutant gliomas (English)

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7 April 2020

2

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7 April 2020

Ghazaleh Tabatabai

7

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7 April 2020

Jens Schittenhelm

8

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7 April 2020

author name string

S Schäfer

1

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7 April 2020

M Skardelly

3

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7 April 2020

M Koch

4

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I Ott

5

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F Paulsen

6

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publication date

23 November 2017

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Neuropathology and Applied Neurobiology

7 April 2020

published in

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volume

44

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issue

2

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page(s)

207-223

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CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012.

7 April 2020

cites work

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Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma

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Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

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ATRX immunostaining predicts IDH and H3F3A status in gliomas

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ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis

21 January 2018

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Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model

21 January 2018

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Identification of OLIG2 as the most specific glioblastoma stem cell marker starting from comparative analysis of data from similar DNA chip microarray platforms

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Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-β Pathway

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Lineage-Restricted OLIG2-RTK Signaling Governs the Molecular Subtype of Glioma Stem-like Cells.

21 January 2018

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The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma

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Olig2 labeling index is correlated with histological and molecular classifications in low-grade diffuse gliomas

21 January 2018

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Human brain factor 1, a new member of the fork head gene family

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FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formation

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Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth

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Diagnostic implications of IDH1-R132H and OLIG2 expression patterns in rare and challenging glioblastoma variants

21 January 2018

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A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas

21 January 2018

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Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors

21 January 2018

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H3F3A K27M mutation in pediatric CNS tumors: a marker for diffuse high-grade astrocytomas

21 January 2018

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Novel molecular stereotactic biopsy procedures reveal intratumoral homogeneity of loss of heterozygosity of 1p/19q and TP53 mutations in World Health Organization grade II gliomas.

21 January 2018

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Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT.

21 January 2018

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IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.

21 January 2018

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Mutational landscape and clonal architecture in grade II and III gliomas

21 January 2018

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Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951.

21 January 2018

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Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

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FOXG1 dysregulation is a frequent event in medulloblastoma

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FoxG1 interacts with Bmi1 to regulate self-renewal and tumorigenicity of medulloblastoma stem cells

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Overexpression of FOXG1 contributes to TGF-beta resistance through inhibition of p21WAF1/CIP1 expression in ovarian cancer

21 January 2018

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IDH1 and IDH2 mutations in gliomas

21 January 2018

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Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 January 2018

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Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors

21 January 2018

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Expression of the Oligodendroglial Lineage-Associated Markers Olig1 and Olig2 in Different Types of Human Gliomas

21 January 2018

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The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas

21 January 2018

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Quantitative analysis of mitotic Olig2 cells in adult human brain and gliomas: implications for glioma histogenesis and biology

21 January 2018

1 reference

Immunohistochemical analysis-based proteomic subclassification of newly diagnosed glioblastomas

21 January 2018

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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

21 January 2018

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Molecular mechanisms of OLIG2 transcription factor in brain cancer.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/NAN.12447

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29053887 AND SRC:MED&resulttype=core&format=json

release_znhwkjfobrdwritm6oueat2jp4

7 April 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/znhwkjfobrdwritm6oueat2jp4

mapped directly with Wikidata item

24 November 2022

based on heuristic

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