HIF activation by pH-dependent nucleolar sequestration of VHL. (Q47385275)

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29 December 2019

title

HIF activation by pH-dependent nucleolar sequestration of VHL (English)

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29 December 2019

1

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29 December 2019

author name string

Lakshman Gunaratnam

series ordinal

2

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29 December 2019

Marie-Eve Bonicalzi

series ordinal

3

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29 December 2019

Stephen Lee

series ordinal

4

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29 December 2019

publication date

6 June 2004

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29 December 2019

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29 December 2019

volume

6

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29 December 2019

issue

7

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29 December 2019

page(s)

642-647

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

29 December 2019

cites work

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7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

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7 January 2021

Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex

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Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus

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Nucleolar Arf sequesters Mdm2 and activates p53

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A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells

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Molecular basis of the VHL hereditary cancer syndrome

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Hypoxia--a key regulatory factor in tumour growth

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Protection by acidotic pH against anoxic cell killing in perfused rat liver: evidence for a pH paradox.

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Neuroprotective effects of glutamate antagonists and extracellular acidity

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Acidosis reduces NMDA receptor activation, glutamate neurotoxicity, and oxygen-glucose deprivation neuronal injury in cortical cultures

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Extracellular acidosis delays cell death against glucose-oxygen deprivation in neuroblastoma x glioma hybrid cells.

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Protective effects of lactic acid on force production in rat skeletal muscle

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Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein

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Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein

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Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C

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Immunostaining of the von Hippel-Lindau gene product in normal and neoplastic human tissues

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On the Origin of Cancer Cells

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Cell and environment interactions in tumor microregions: the multicell spheroid model

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Tumour suppression by the human von Hippel-Lindau gene product

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The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

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Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

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7 January 2021

Role of exon 2-encoded beta -domain of the von Hippel-Lindau tumor suppressor protein

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7 January 2021

Hypoxia inducible factor activates the transforming growth factor-alpha/epidermal growth factor receptor growth stimulatory pathway in VHL(-/-) renal cell carcinoma cells

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7 January 2021

Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1

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7 January 2021

VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia

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7 January 2021

Mitotic treasures in the nucleolus

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7 January 2021