DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma. (Q47377422)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162699 AND SRC:MED&resulttype=core&format=json

3 April 2020

title

DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162699 AND SRC:MED&resulttype=core&format=json

fibrolamellar hepatocellular carcinoma

3 April 2020

main subject

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author

Sanford M Simon

11

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3 April 2020

David Requena

7

1 reference

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3 April 2020

author name string

Edward R Kastenhuber

1

1 reference

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3 April 2020

Gadi Lalazar

2

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3 April 2020

Shauna L Houlihan

3

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3 April 2020

Darjus F Tschaharganeh

4

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3 April 2020

Timour Baslan

5

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3 April 2020

Chi-Chao Chen

6

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3 April 2020

Sha Tian

8

1 reference

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3 April 2020

Benedikt Bosbach

9

1 reference

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3 April 2020

John E Wilkinson

10

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3 April 2020

Scott W Lowe

12

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3 April 2020

language of work or name

English

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publication date

21 November 2017

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Proceedings of the National Academy of Sciences of the United States of America

3 April 2020

published in

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3 April 2020

volume

114

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3 April 2020

issue

50

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3 April 2020

page(s)

13076-13084

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describes a project that uses

3 April 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5740683

inferred from PubMed Central ID database lookup

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Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma.

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Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells

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DNAJB1-PRKACA is specific for fibrolamellar carcinoma.

24 June 2018

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Unique genomic profile of fibrolamellar hepatocellular carcinoma

24 June 2018

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Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma

24 June 2018

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24 June 2018

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24 June 2018

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24 June 2018

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24 June 2018

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24 June 2018

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24 June 2018

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24 June 2018

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24 June 2018

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Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination

24 June 2018

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24 June 2018

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24 June 2018

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24 June 2018

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CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma.

24 June 2018

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14 August 2018

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Environmental exposures as a risk factor for fibrolamellar carcinoma.

14 August 2018

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mTORC1 and FGFR1 signaling in fibrolamellar hepatocellular carcinoma.

14 August 2018

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β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis

14 August 2018

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Consequences of lysine 72 mutation on the phosphorylation and activation state of cAMP-dependent kinase

14 August 2018

1 reference

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Fibrolamellar carcinoma of liver: a primary malignant oncocytic carcinoid?

14 August 2018

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12 December 2020

Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease

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12 December 2020

Fibrolamellar carcinomas show overexpression of genes in the RAS, MAPK, PIK3, and xenobiotic degradation pathways

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12 December 2020

Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1716483114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162699 AND SRC:MED&resulttype=core&format=json

release_ouxrwus5fffpnbyw7uqvvaskfa

3 April 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ouxrwus5fffpnbyw7uqvvaskfa

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162699 AND SRC:MED&resulttype=core&format=json

3 April 2020

PubMed publication ID

29162699

1 reference