RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions (Q47269284)

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scientific article published on 20 December 2017

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English	RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions	scientific article published on 20 December 2017

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scholarly article

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PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/29263218

RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions (English)

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Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/29263218

Langerhans cell histiocytosis specific to childhood

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based on heuristic

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based on heuristic

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4

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31 May 2020

Jerry E. Chipuk

21

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31 May 2020

Camille Bigenwald

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31 May 2020

13

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31 May 2020

Kenneth L McClain

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31 May 2020

Willem J.M. Mulder

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31 May 2020

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31 May 2020

Marylene Leboeuf

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Marylene Leboeuf

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31 May 2020

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Brandon Hogstad

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31 May 2020

Marie-Luise Berres

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31 May 2020

Rikhia Chakraborty

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31 May 2020

Madhavika Serasinghe

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31 May 2020

Karen Phaik Har Lim

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31 May 2020

Romain Remark

10

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31 May 2020

Samantha Baxter

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31 May 2020

Veronika Kana

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31 May 2020

Wing-Hong Kwan

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31 May 2020

Elisa Brandt

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31 May 2020

Helene Salmon

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31 May 2020

Poulikos Poulikakos

20

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31 May 2020

Carl E Allen

23

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31 May 2020

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publication date

20 December 2017

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13 January 2018

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Journal of Experimental Medicine

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31 May 2020

215

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31 May 2020

1

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31 May 2020

319-336

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31 May 2020

In-depth tissue profiling using multiplexed immunohistochemical consecutive staining on single slide

1 reference

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26 August 2018

Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis

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Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88.

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Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation

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Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations

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MAP2K1 and MAP3K1 mutations in Langerhans cell histiocytosis.

1 reference

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How I treat Langerhans cell histiocytosis

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Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

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HDL-mimetic PLGA nanoparticle to target atherosclerosis plaque macrophages

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Progress in understanding the pathogenesis of Langerhans cell histiocytosis: back to Histiocytosis X?

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Reproducible and sustained efficacy of targeted therapy with vemurafenib in patients with BRAF(V600E)-mutated Erdheim-Chester disease.

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Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

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High prevalence of somatic MAP2K1 mutations in BRAF V600E-negative Langerhans cell histiocytosis.

1 reference

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26 August 2018

Somatic activating ARAF mutations in Langerhans cell histiocytosis.

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BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups

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A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation

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Pathological consequence of misguided dendritic cell differentiation in histiocytic diseases

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Signatures of mutational processes in human cancer

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Targeting BCL2 family in human myeloid dendritic cells: a challenge to cure diseases with chronic inflammations associated with bone loss

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26 August 2018

Therapy prolongation improves outcome in multisystem Langerhans cell histiocytosis

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26 August 2018

Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells.

1 reference

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26 August 2018

BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis.

1 reference

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26 August 2018

Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial

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26 August 2018

Deciphering the transcriptional network of the dendritic cell lineage

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GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells

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RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors

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Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease

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26 August 2018

Dendritic Cell and Macrophage Heterogeneity In Vivo

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26 August 2018

Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

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26 August 2018

TGF-beta is required to maintain the pool of immature Langerhans cells in the epidermis.

1 reference

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26 August 2018

Recurrent BRAF mutations in Langerhans cell histiocytosis

1 reference

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Requirement of CCL17 for CCR7- and CXCR4-dependent migration of cutaneous dendritic cells

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GM-CSF-dependent, CD103 dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization.

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26 August 2018

Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells

1 reference

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Langerhans cell histiocytosis: Current concepts and treatments

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1 reference

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ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence

1 reference

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Reactivations in multisystem Langerhans cell histiocytosis: data of the international LCH registry

1 reference

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Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells

1 reference

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CXCL12-CXCR4 engagement is required for migration of cutaneous dendritic cells

1 reference

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Expansion of regulatory T cells in patients with Langerhans cell histiocytosis

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Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen.

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Inflammation, lymphatic function, and dendritic cell migration

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A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

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26 August 2018

Dendritic-cell trafficking to lymph nodes through lymphatic vessels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5748846

26 August 2018

Permanent consequences in Langerhans cell histiocytosis patients: a pilot study from the Histiocyte Society-Late Effects Study Group.

1 reference

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26 August 2018

Aberrant chemokine receptor expression and chemokine production by Langerhans cells underlies the pathogenesis of Langerhans cell histiocytosis.

1 reference

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CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

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Controversies and new approaches to treatment of Langerhans cell histiocytosis

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26 August 2018

TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor

1 reference

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26 August 2018

Langerhans'-cell histiocytosis (histiocytosis X)--a clonal proliferative disease.

1 reference

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26 August 2018

Clonal proliferation of Langerhans cells in Langerhans cell histiocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29263218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coincident expression of the chemokine receptors CCR6 and CCR7 by pathologic Langerhans cells in Langerhans cell histiocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29263218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-alpha enhances phenotypic and functional maturation of human epidermal Langerhans cells and induces IL-12 p40 and IP-10/CXCL-10 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/29263218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle proteins to monitor cancer of salivary glands

1 reference

https://pubmed.ncbi.nlm.nih.gov/29263218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29263218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.20161881

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263218 AND SRC:MED&resulttype=core&format=json

31 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263218 AND SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29263218 AND SRC:MED&resulttype=core&format=json

31 May 2020

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