Mutations affecting either generation or survival of cells influence the pool size of mature B cells (Q47263297)

12 January 2018

title

Mutations affecting either generation or survival of cells influence the pool size of mature B cells (English)

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12 January 2018

author name string

Rolink AG

1

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12 January 2018

Brocker T

2

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12 January 2018

Bluethmann H

3

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12 January 2018

Kosco-Vilbois MH

4

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12 January 2018

Andersson J

5

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12 January 2018

Melchers F

6

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12 January 2018

language of work or name

English

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publication date

1 May 1999

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12 January 2018

published in

Immunity

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12 January 2018

volume

10

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12 January 2018

issue

5

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12 January 2018

page(s)

619-628

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12 January 2018

In vivo expression and function of hybrid Ia dimers (E alpha A beta) in recombinant and transgenic mice

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Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo

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Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression

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Analysis of the B-cell progenitor compartment at the level of single cells.

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The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow

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Depletion of CD4 T cells in major histocompatibility complex class II-deficient mice.

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Study of murine B-cell development through analysis of immunoglobulin variable region genes

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Demonstration of B-cell maturation in X-linked immunodeficient mice by simultaneous three-colour immunofluorescence

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Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

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CD4/major histocompatibility complex class II interaction analyzed with CD4‐ and lymphocyte activation gene‐3 (LAG‐3)‐Ig fusion proteins

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Defective B cell development and function in Btk-deficient mice

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Impaired B cell maturation in mice lacking Bruton's tyrosine kinase (Btk) and CD40

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A re‐evaluation of the effects of X‐linked immunodeficiency (xid) mutation on B cell differentiation and function in the mouse

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Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

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In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

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Newly produced virgin B cells migrate to secondary lymphoid organs but their capacity to enter follicles is restricted

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Antigen-driven selection of virgin and memory B cells

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The dynamic relationship between B-cell populations in adults

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Antigen-reactive T cell clones restricted by mixed isotype A beta d/E alpha d class II molecules

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Independent modes of natural killing distinguished in mice lacking Lag3

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The Bcl-2 family and cell death regulation

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Profound reduction of mature B cell numbers, reactivities and serum Ig levels in mice which simultaneously carry the XID and CD40 deficiency genes

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7 January 2021

Proliferation kinetics and the lifespan of B cells in central and peripheral lymphoid organs

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Normal development and function of CD8 cells but markedly decreased helper cell activity in mice lacking CD4

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IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development

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7 January 2021

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

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7 January 2021

Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity.

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7 January 2021

Requirement for invariant chain in B cell maturation and function.

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Differential requirements for survival and proliferation of CD8 naïve or memory T cells

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Direct demonstration of MHC class II surface expression on murine pre-B cells

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The status of Ig loci rearrangements in single cells from different stages of B cell development

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Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR Complex

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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7 January 2021

Transgenic mice selectively lacking MHC class II (I-E) antigen expression on B cells: an in vivo approach to investigate Ia gene function

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7 January 2021

Functional expression of a microinjected Ed alpha gene in C57BL/6 transgenic mice

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7 January 2021

10.1016/S1074-7613(00)80061-8

Identifiers

DOI

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12 January 2018

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12 January 2018