Lesion Bypass and the Reactivation of Stalled Replication Forks. (Q47235095)

PubMed publication ID

29298091

12 January 2018

http://europepmc.org/abstract/MED/29298091

title

Lesion Bypass and the Reactivation of Stalled Replication Forks (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6419508&resulttype=core&format=json

13 May 2020

author name string

Kenneth J Marians

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6419508&resulttype=core&format=json

13 May 2020

publication date

3 January 2018

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PubMed publication ID

29298091

12 January 2018

http://europepmc.org/abstract/MED/29298091

number of pages

22

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Annual Review of Biochemistry

inferred from page(s)

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6419508&resulttype=core&format=json

13 May 2020

volume

87

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6419508&resulttype=core&format=json

13 May 2020

page(s)

217-238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6419508&resulttype=core&format=json

Isolation and characterization of mutants of Escherichia coli deficient in induction of mutations by ultraviolet light

13 May 2020

cites work

1 reference

12 December 2020

Uvm mutants of Escherichia coli K12 deficient in UV mutagenesis. I. Isolation of uvm mutants and their phenotypical characterization in DNA repair and mutagenesis

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12 December 2020

Mutagenic DNA repair in Escherichia coli. III. Requirement for a function of DNA polymerase III in ultraviolet-light mutagenesis

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12 December 2020

Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli

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12 December 2020

A model for replication repair in mammalian cells

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12 December 2020

Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III

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12 December 2020

Nature of the SOS-inducing signal in Escherichia coli. The involvement of DNA replication.

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12 December 2020

DNA polymerase III of Escherichia coli is required for UV and ethyl methanesulfonate mutagenesis

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12 December 2020

Capacity of RecA protein to bind preferentially to UV lesions and inhibit the editing subunit (epsilon) of DNA polymerase III: a possible mechanism for SOS-induced targeted mutagenesis

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12 December 2020

Post-Replication Repair of DNA in Ultraviolet-Irradiated Mammalian Cells. No Gaps in DNA Synthesized Late after Ultraviolet Irradiation

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12 December 2020

Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiation

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12 December 2020

Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains

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12 December 2020

Characterization of postreplication repair in Saccharomyces cerevisiae and effects of rad6, rad18, rev3 and rad52 mutations

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12 December 2020

UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.

1 reference

12 December 2020

The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis

1 reference

12 December 2020

The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication

1 reference

12 December 2020

Replisome assembly at oriC, the replication origin of E. coli, reveals an explanation for initiation sites outside an origin

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12 December 2020

The DNA replication checkpoint response stabilizes stalled replication forks

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12 December 2020

Structural analysis of DNA replication fork reversal by RecG

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12 December 2020

Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines

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12 December 2020

Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects

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12 December 2020

ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.

1 reference

12 December 2020

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

1 reference

12 December 2020

DNA damage-induced replication fork regression and processing in Escherichia coli.

1 reference

12 December 2020

PriA mediates DNA replication pathway choice at recombination intermediates

1 reference

12 December 2020

Fate of DNA replication fork encountering a single DNA lesion during oriC plasmid DNA replication in vitro

1 reference

12 December 2020

DNA helicase Srs2 disrupts the Rad51 presynaptic filament

1 reference

12 December 2020

The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.

1 reference

12 December 2020

Uncoupling of leading- and lagging-strand DNA replication during lesion bypass in vivo

1 reference

12 December 2020

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

1 reference

12 December 2020

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

1 reference

12 December 2020

Functional uncoupling of twin polymerases: mechanism of polymerase dissociation from a lagging-strand block.

1 reference

12 December 2020

Enzymatic switching for efficient and accurate translesion DNA replication.

1 reference

12 December 2020

The disposition of nascent strands at stalled replication forks dictates the pathway of replisome loading during restart

1 reference

12 December 2020

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

1 reference

12 December 2020

SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase

1 reference

12 December 2020

Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: structural insights and new members

1 reference

12 December 2020

Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.

1 reference

12 December 2020

A sliding-clamp toolbelt binds high- and low-fidelity DNA polymerases simultaneously.

1 reference

12 December 2020

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis

1 reference

12 December 2020

Multiple Mechanisms Control Chromosome Integrity after Replication Fork Uncoupling and Restart at Irreparable UV Lesions

1 reference

12 December 2020

Replication fork reactivation downstream of a blocked nascent leading strand

1 reference

12 December 2020

DNA primase acts as a molecular brake in DNA replication

1 reference

12 December 2020

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

1 reference

12 December 2020

REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo

1 reference

12 December 2020

Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork

1 reference

12 December 2020

UV irradiation induces a postreplication DNA damage checkpoint

1 reference

12 December 2020

Break-induced replication and telomerase-independent telomere maintenance require Pol32.

1 reference

12 December 2020

What a difference a decade makes: insights into translesion DNA synthesis

1 reference

12 December 2020

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments

1 reference

12 December 2020

Novel pro- and anti-recombination activities of the Bloom's syndrome helicase

1 reference

12 December 2020

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

1 reference

12 December 2020

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

1 reference

12 December 2020

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.

1 reference

12 December 2020

DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers

1 reference

12 December 2020

Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase.

1 reference

12 December 2020

Replication fork reversal and the maintenance of genome stability

1 reference

12 December 2020

Coordinating DNA replication by means of priming loop and differential synthesis rate

1 reference

12 December 2020

Multiple two-polymerase mechanisms in mammalian translesion DNA synthesis.

1 reference

12 December 2020

Postreplication gaps at UV lesions are signals for checkpoint activation

1 reference

12 December 2020

Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex.

1 reference

12 December 2020

Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

1 reference

12 December 2020

Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands

1 reference

12 December 2020

Replication and recombination factors contributing to recombination-dependent bypass of DNA lesions by template switch

1 reference

12 December 2020

Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression.

1 reference

12 December 2020

Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

1 reference

12 December 2020

UV stalled replication forks restart by re-priming in human fibroblasts

1 reference

12 December 2020

DNA replicases from a bacterial perspective

1 reference

12 December 2020

Analysis of protein dynamics at active, stalled, and collapsed replication forks.

1 reference

12 December 2020

The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell nuclear antigen (PCNA) regulates the Rev1-PCNA interaction and Polζ/Rev1-dependent translesion DNA synthesis

1 reference

12 December 2020

The Escherichia coli replisome is inherently DNA damage tolerant

1 reference

12 December 2020

Increase in dNTP pool size during the DNA damage response plays a key role in spontaneous and induced-mutagenesis in Escherichia coli

1 reference

12 December 2020

RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks

1 reference

12 December 2020

Inhibition of homologous recombination by the PCNA-interacting protein PARI

1 reference

12 December 2020

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2

1 reference

12 December 2020

Topoisomerase I poisoning results in PARP-mediated replication fork reversal

1 reference

12 December 2020

Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1

1 reference

12 December 2020

Competition, collaboration and coordination--determining how cells bypass DNA damage.

1 reference

12 December 2020

A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

1 reference

12 December 2020

Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway

1 reference

12 December 2020

Direct observation of stalled fork restart via fork regression in the T4 replication system.

1 reference

12 December 2020

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

1 reference

12 December 2020

A proteomic characterization of factors enriched at nascent DNA molecules

1 reference

12 December 2020

Rescuing stalled or damaged replication forks

1 reference

12 December 2020

Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination

1 reference

12 December 2020

Substrate-selective repair and restart of replication forks by DNA translocases

1 reference

12 December 2020

NMR mapping of PCNA interaction with translesion synthesis DNA polymerase Rev1 mediated by Rev1-BRCT domain

1 reference

12 December 2020

Translesion DNA polymerases

1 reference

12 December 2020

The accumulation of DNA repair defects is the molecular origin of carcinogenesis.

1 reference

12 December 2020

Causes of genome instability

1 reference

12 December 2020

FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling.

1 reference

12 December 2020

hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity

1 reference

12 December 2020

PrimPol, an archaic primase/polymerase operating in human cells

1 reference

12 December 2020

Repriming of DNA synthesis at stalled replication forks by human PrimPol

1 reference

12 December 2020

PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome

1 reference

12 December 2020

PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication

1 reference

12 December 2020

Dynamics of leading-strand lesion skipping by the replisome

1 reference

12 December 2020

A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome.

1 reference

12 December 2020

Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis

1 reference

12 December 2020

Regression of replication forks stalled by leading-strand template damage: I. Both RecG and RuvAB catalyze regression, but RuvC cleaves the holliday junctions formed by RecG preferentially

1 reference

12 December 2020

Visualization of recombination-mediated damage bypass by template switching

1 reference

12 December 2020

CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication.

1 reference

12 December 2020

DNA replication stress as a hallmark of cancer

1 reference

12 December 2020

The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ.

1 reference

12 December 2020

Error-free DNA damage tolerance and sister chromatid proximity during DNA replication rely on the Polα/Primase/Ctf4 Complex

1 reference

12 December 2020

Replication fork reversal in eukaryotes: from dead end to dynamic response

1 reference

12 December 2020

DNA2 drives processing and restart of reversed replication forks in human cells.

1 reference

12 December 2020

Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells

1 reference

12 December 2020

Regulated eukaryotic DNA replication origin firing with purified proteins

1 reference

12 December 2020

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation.

1 reference

12 December 2020

Error-free DNA-damage tolerance in Saccharomyces cerevisiae.

1 reference

12 December 2020

DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.

1 reference

12 December 2020

Regulation of Mutagenic DNA Polymerase V Activation in Space and Time

1 reference

12 December 2020

Polymerase δ replicates both strands after homologous recombination-dependent fork restart

1 reference

12 December 2020

Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication

1 reference

12 December 2020

cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ.

1 reference

12 December 2020

The architecture of a eukaryotic replisome.

1 reference

12 December 2020

Rad51 recombinase prevents Mre11 nuclease-dependent degradation and excessive PrimPol-mediated elongation of nascent DNA after UV irradiation.

1 reference

12 December 2020

The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis

1 reference

12 December 2020

The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1

1 reference

12 December 2020

DNA Polymerase III, but Not Polymerase IV, Must Be Bound to a τ-Containing DnaX Complex to Enable Exchange into Replication Forks

1 reference

12 December 2020

In vivo evidence for translesion synthesis by the replicative DNA polymerase δ.

1 reference

12 December 2020

Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides

1 reference

12 December 2020

DNA damage tolerance by recombination: Molecular pathways and DNA structures

1 reference

12 December 2020

PCNA tool belts and polymerase bridges form during translesion synthesis

1 reference

12 December 2020

Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates.

1 reference

12 December 2020

Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase

1 reference

12 December 2020

Functions, Regulation, and Therapeutic Implications of the ATR Checkpoint Pathway

1 reference

12 December 2020

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion

1 reference

12 December 2020

Chromatin Constrains the Initiation and Elongation of DNA Replication.

1 reference

12 December 2020

Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

1 reference

12 December 2020

How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication.

1 reference

12 December 2020

Quality control mechanisms exclude incorrect polymerases from the eukaryotic replication fork

1 reference

12 December 2020

Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases.

1 reference

12 December 2020

Moonlighting at replication forks - a new life for homologous recombination proteins BRCA1, BRCA2 and RAD51.

1 reference

12 December 2020

Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation

1 reference

12 December 2020

Mechanisms for initiating cellular DNA replication

1 reference

12 December 2020

Eukaryotic DNA Replication Fork.

1 reference

12 December 2020

Replication Restart in Bacteria

1 reference

12 December 2020

Building up and breaking down: mechanisms controlling recombination during replication

1 reference

12 December 2020

Frequent exchange of the DNA polymerase during bacterial chromosome replication.

1 reference

12 December 2020

CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome

1 reference

12 December 2020

Break induced replication in eukaryotes: mechanisms, functions, and consequences.

1 reference

12 December 2020

Single-molecule visualization of fast polymerase turnover in the bacterial replisome

1 reference

12 December 2020

Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours around the Same Obstacle

1 reference

12 December 2020

Independent and Stochastic Action of DNA Polymerases in the Replisome.

1 reference

12 December 2020

Replication Catastrophe: When a Checkpoint Fails because of Exhaustion

1 reference

12 December 2020

Replisome-mediated translesion synthesis by a cellular replicase.

1 reference

12 December 2020

The impact of replication stress on replication dynamics and DNA damage in vertebrate cells.

1 reference

12 December 2020

RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.

1 reference

12 December 2020

Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments

1 reference

12 December 2020

Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses

1 reference

12 December 2020

Replication-Transcription Conflicts Generate R-Loops that Orchestrate Bacterial Stress Survival and Pathogenesis

1 reference

12 December 2020

10.1146/ANNUREV-BIOCHEM-062917-011921

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6419508&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6419508&resulttype=core&format=json

13 May 2020

PubMed publication ID

29298091

1 reference