Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis (Q47160964)

http://europepmc.org/abstract/PMC/5731848

10 January 2018

title

Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis (English)

1 reference

http://europepmc.org/abstract/PMC/5731848

10 January 2018

author

Francesco Berardinelli

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Gabriele Babini

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Mirella Tanori

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Arianna Casciati

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Simona Leonardi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Emanuela Pasquali

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Francesca Antonelli

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Barbara Tanno

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Paola Giardullo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Alessandro Pannicelli

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Ilaria De Stefano

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Antonella Sgura

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Mariateresa Mancuso

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Anna Saran

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

Simonetta Pazzaglia

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

7 July 2016

1 reference

http://europepmc.org/abstract/PMC/5731848

10 January 2018

published in

Oncotarget

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

issue

60

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

100958-100974

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

13 June 2020

cites work

1 reference

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23 May 2018

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Functional Aspects of PARP1 in DNA Repair and Transcription

23 May 2018

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Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters

23 May 2018

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A comparison of gene set analysis methods in terms of sensitivity, prioritization and specificity

23 May 2018

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SIRT6 modulates paclitaxel and epirubicin resistance and survival in breast cancer.

23 May 2018

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Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer

23 May 2018

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Replication fork dynamics and the DNA damage response.

23 May 2018

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Inhibition of DNA-dependent protein kinase induces accelerated senescence in irradiated human cancer cells

23 May 2018

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Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells.

23 May 2018

1 reference

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p53 Upregulation Is a Frequent Response to Deficiency of Cell-Essential Genes

23 May 2018

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Pathways of mammalian replication fork restart.

23 May 2018

1 reference

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Overexpression of the pituitary tumor transforming gene induces p53-dependent senescence through activating DNA damage response pathway in normal human fibroblasts

23 May 2018

1 reference

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Mouse models of p53 functions

23 May 2018

1 reference

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PARP inhibition: PARP1 and beyond

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

23 May 2018

1 reference

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23 May 2018

Modes of p53 regulation

1 reference

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ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

23 May 2018

1 reference

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Rad54 protein promotes branch migration of Holliday junctions

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

23 May 2018

1 reference

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

23 May 2018

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23 May 2018

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Modulation of patched-associated susceptibility to radiation induced tumorigenesis by genetic background

23 May 2018

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Pathways for mitotic homologous recombination in mammalian cells

23 May 2018

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23 May 2018

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Functional interaction between DNA-PKcs and telomerase in telomere length maintenance

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1 heterozygous mice

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

23 May 2018

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Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development

23 May 2018

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Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis

23 May 2018

1 reference

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Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage

23 May 2018

1 reference

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DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

23 May 2018

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Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

23 May 2018

1 reference

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Homologous and non-homologous recombination differentially affect DNA damage repair in mice

23 May 2018

1 reference

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Mutations in the RAD54 recombination gene in primary cancers

23 May 2018

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Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer

23 May 2018

1 reference

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A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

23 May 2018

1 reference

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Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Altered Neural Cell Fates and Medulloblastoma in Mouse patched Mutants

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Recombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Cancer. Potential of the synthetic lethality principle

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Developmental and oncogenic radiation effects on neural stem cells and their differentiating progeny in mouse cerebellum

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

PARP-1 cooperates with Ptc1 to suppress medulloblastoma and basal cell carcinoma.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Two-hit model for progression of medulloblastoma preneoplasia in Patched heterozygous mice.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Linking DNA damage to medulloblastoma tumorigenesis in patched heterozygous knockout mice.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Multiple interactions with the Rad51 recombinase govern the homologous recombination function of Rad54.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5731848

Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29254138

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Les ataxies cérébelleuses autosomiques récessives

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29254138

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.10479

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29254138 AND SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

29254138

1 reference