Scientific Opinion on Dietary Reference Values for vitamin E as α-tocopherol (Q47157084)

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Maternal vitamin D and E intakes during pregnancy are associated with asthma in children

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Serum and dietary beta-carotene and alpha-tocopherol and incidence of type 2 diabetes mellitus in a community-based study of Swedish men: report from the Uppsala Longitudinal Study of Adult Men (ULSAM) study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Gender differences in food and nutrient intakes and status indices from the National Diet and Nutrition Survey of people aged 65 years and over

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Dietary vitamins E and C and prostate cancer risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Dietary factors and the risk of testicular cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Bioavailability of vitamin E in humans: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Canalicular bile secretion in man. Studies utilizing the biliary clearance of (14C)mannitol

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Minerals and vitamins and the risk of bladder cancer: results from the New Hampshire Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Ataxia with Isolated Vitamin E Deficiency: Heterogeneity of Mutations and Phenotypic Variability in a Large Number of Families

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin A and E content of human milk at early stages of lactation

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Biokinetics in humans of RRR-alpha-tocopherol: the free phenol, acetate ester, and succinate ester forms of vitamin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Quantitation of [5-CH3]-(2R, 4'R, 8'R)-α-Tocopherol in Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

In Vivo Formation of 8-Epi-Prostaglandin F 2α Is Increased in Hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general practice. Collaborative Group of the Primary Prevention Project

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Low maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Increased vitamin E intake is associated with higher alpha-tocopherol concentration in the maternal circulation but higher alpha-carboxyethyl hydroxychroman concentration in the fetal circulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Intake of dietary fat and vitamin in relation to breast cancer risk in Korean women: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Recent advances in vitamin E metabolism and deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

ON THE EXISTENCE OF A HITHERTO UNRECOGNIZED DIETARY FACTOR ESSENTIAL FOR REPRODUCTION.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Antioxidant supplements to prevent or slow down the progression of AMD: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Risk of ovarian carcinoma and consumption of vitamins A, C, and E and specific carotenoids: a prospective analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

The occurrence and effects of human vitamin E deficiency. A study in patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Selected micronutrient intake and the risk of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Premenopausal breast cancer risk and intake of vegetables, fruits, and related nutrients

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamins and carotenoids intake and the risk of basal cell carcinoma of the skin in women (United States).

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

The maximal amount of alpha-tocopherol intake from foods alone in U.S. adults (1994-1996 CSFII): an analysis by linear programming.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Unleashing the untold and misunderstood observations on vitamin E

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Dietary intakes of selected nutrients and food groups and risk of cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Scleroderma and repeated spontaneous abortions treated with vitamin E--a case report--.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS).

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Dietary vitamin C, E, and carotenoid intake and risk of renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Intestinal lipid absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin C and vitamin E supplement use and bladder cancer mortality in a large cohort of US men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

The absorption of vitamin E is influenced by the amount of fat in a meal and the food matrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry-based metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Human placental trophoblast cells express alpha-tocopherol transfer protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Antioxidant intake and primary open-angle glaucoma: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Time course of vitamin E repletion in the premature infant

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Intakes of vitamin A, C, and E, and beta-carotene are associated with risk of cervical cancer: a case-control study in Korea

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Case-control study of malignant melanoma in Washington State. II. Diet, alcohol, and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Baseline selenium status and effects of selenium and vitamin e supplementation on prostate cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Urinary α-carboxyethyl hydroxychroman can be used as a predictor of α-tocopherol adequacy, as demonstrated in the Energetics Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Polymorphisms in the CD36/FAT gene are associated with plasma vitamin E concentrations in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Carotenoids and tocopherols in various hepatobiliary conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Dietary alpha-, beta-, gamma- and delta-tocopherols in lung cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

The alpha-tocopherol transfer protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Intake of alpha-tocopherol is limited among US adults

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Ataxia with isolated vitamin E deficiency: neurological phenotype, clinical follow-up and novel mutations in TTPA gene in Italian families

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Antioxidant intake in pregnancy in relation to wheeze and eczema in the first two years of life

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Concentrations of alpha- and gamma-tocopherols in human breast milk during the first months of lactation and in infant formulas.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Oxidative stress in athletes during extreme endurance exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Effects of vitamin E on lipid peroxidation in healthy persons

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin E and respiratory tract infections in elderly nursing home residents: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Dietary intake of antioxidant vitamins and risk of Parkinson's disease: a case-control study in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Ultra-High-Pressure Liquid Chromatographic method for the analysis of tocopherols in human colostrum and milk

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Localization of alpha-tocopherol transfer protein in trophoblast, fetal capillaries' endothelium and amnion epithelium of human term placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin E--its role in neurological function

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Antioxidants, carotenoids, and risk of rectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Regulatory mechanisms to control tissue alpha-tocopherol.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Alpha-tocopherol beta-oxidation localized to rat liver mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Dietary beta-carotene, vitamin C and E intake and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Dynamics of lipid peroxidation and its inhibition by antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Role of vitamin E as a lipid-soluble peroxyl radical scavenger: in vitro and in vivo evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Intake of vitamins A, C, and E from diet and supplements and breast cancer in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

This kinetic, bioavailability, and metabolism study of RRR-α-tocopherol in healthy adults suggests lower intake requirements than previous estimates

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Repeated measurements of vegetables, fruits, beta-carotene, and vitamins C and E in relation to lung cancer. The Zutphen Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

The influence of maternal smoking on maternal and newborn oxidant and antioxidant status

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Direct observation of a free radical interaction between vitamin E and vitamin C

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Synthesis and analysis of conjugates of the major vitamin E metabolite, alpha-CEHC.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Effects of maternal antioxidant supplementation on maternal and fetal antioxidant levels: a randomized, double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Coenzyme Q concentration and total antioxidant capacity of human milk at different stages of lactation in mothers of preterm and full-term infants.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

ATP-binding cassette transporter A1 is significantly involved in the intestinal absorption of alpha- and gamma-tocopherol but not in that of retinyl palmitate in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Utility of Breath Ethane as a Noninvasive Biomarker of Vitamin E Status in Children

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Diet and bladder cancer in Spain: A multi-centre case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Absorption, transport, and tissue delivery of vitamin E

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

The relationship between dose of vitamin E and suppression of oxidative stress in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Immunohistochemical localization of alpha-tocopherol transfer protein and lipoperoxidation products in human first-trimester and term placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Effect of the stage of lactation in humans on carotenoid levels in milk, blood plasma and plasma lipoprotein fractions

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

A prospective study of vitamin intake and the risk of hearing loss in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

ATP-binding cassette transporter A1 is involved in hepatic alpha-tocopherol secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Biochemical validation of food frequency questionnaire-estimated carotenoid, alpha-tocopherol, and folate intakes among African Americans and non-Hispanic Whites in the Southern Community Cohort Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin E and colon cancer: is there an association?

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Multivitamins, individual vitamin and mineral supplements, and risk of diabetes among older U.S. adults

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Influence of major structural features of tocopherols and tocotrienols on their omega-oxidation by tocopherol-omega-hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Accumulation of ceroid in smooth muscle indicates severe malabsorption and vitamin E deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Tocopherol-binding proteins: their function and physiological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Antioxidant capacity of human milk and its association with vitamins A and E and fatty acid composition

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Serum vitamin E concentration and osmotic fragility in female long-distance runners

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Alpha-tocopherol (vitamin E) and beta-carotene supplementation does not affect the risk for large abdominal aortic aneurysm in a controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Postintervention effect of alpha tocopherol and beta carotene on different strokes: a 6-year follow-up of the Alpha Tocopherol, Beta Carotene Cancer Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Effect of alpha-tocopherol and beta-carotene supplementation on coronary heart disease during the 6-year post-trial follow-up in the ATBC study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin E, antioxidant and nothing more

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin E regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Mechanisms for the prevention of vitamin E excess

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Expression of the α-tocopherol transfer protein gene is regulated by oxidative stress and common single-nucleotide polymorphisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Relationship between vitamin E requirement and polyunsaturated fatty acid intake in man: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Human milk vitamin content after pasteurisation, storage, or tube feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin E and C supplementation and risk of cancer in men: posttrial follow-up in the Physicians' Health Study II randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Vitamin E and its function in membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Supplemental and dietary vitamin E intakes and risk of prostate cancer in a large prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

21 January 2018

Vitamin E metabolism.

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Nutritional factors in relation to endometrial cancer: a report from a population-based case-control study in Shanghai, China

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Addition products of alpha-tocopherol with lipid-derived free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Validation of an FFQ to assess antioxidant intake in overweight postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Validation of an FFQ to assess short-term antioxidant intake against 30 d food records and plasma biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Diet and breast cancer in Shanghai and Tianjin, China

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Abetalipoproteinemia: two case reports and literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Antioxidant intake and risk of osteoporotic hip fracture in Utah: an effect modified by smoking status.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Analysis of multiple metabolites of tocopherols and tocotrienols in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Genetic polymorphisms as determinants for disease-preventive effects of vitamin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Adolescent diet and risk of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

Effect of α-Tocopherol (Vitamin E) and β-Carotene Supplementation on the Incidence of Intermittent Claudication in Male Smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.2903/J.EFSA.2015.4149

21 January 2018

Identifiers

DOI

10.2903/J.EFSA.2015.4149

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5owhvlofizbx5n76cgdvy3itcq

mapped directly with Wikidata item

30 July 2022

based on heuristic

Fatcat ID

release_5owhvlofizbx5n76cgdvy3itcq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5owhvlofizbx5n76cgdvy3itcq