Fosfomycin: Pharmacological, Clinical and Future Perspectives. (Q47136072)

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8 April 2020

title

Fosfomycin: Pharmacological, Clinical and Future Perspectives (English)

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8 April 2020

6

Cees van Nieuwkoop

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8 April 2020

Jasper Stevens

8

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8 April 2020

Daniel Touw

7

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8 April 2020

3

Jacobus Burggraaf

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8 April 2020

author name string

Anneke Corinne Dijkmans

1

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8 April 2020

Natalia Veneranda Ortiz Zacarías

2

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8 April 2020

Johan Willem Mouton

4

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8 April 2020

Erik Bert Wilms

5

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8 April 2020

Ingrid Maria Catharina Kamerling

9

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8 April 2020

publication date

31 October 2017

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Antibiotics (Basel, Switzerland)

8 April 2020

published in

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8 April 2020

volume

6

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8 April 2020

issue

4

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Creative Commons Attribution 4.0 International

8 April 2020

copyright license

start time

31 October 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing of Pseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance.

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Molecular Mechanisms and Clinical Impact of Acquired and Intrinsic Fosfomycin Resistance

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Fosfomycin versus meropenem in bacteraemic urinary tract infections caused by extended-spectrum β-lactamase-producing Escherichia coli (FOREST): study protocol for an investigator-driven randomised controlled trial

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Evaluation of three-dose fosfomycin tromethamine in the treatment of patients with urinary tract infections: an uncontrolled, open-label, multicentre study

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Is fosfomycin a potential treatment alternative for multidrug-resistant gram-negative prostatitis?

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'Old' antibiotics for emerging multidrug-resistant bacteria

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The role of pharmacokinetics/pharmacodynamics in setting clinical MIC breakpoints: the EUCAST approach

23 May 2018

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Tackling antibiotic resistance

23 May 2018

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The revival of fosfomycin

23 May 2018

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Antimicrobial susceptibilities of commonly encountered bacterial isolates to fosfomycin determined by agar dilution and disk diffusion methods

23 May 2018

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Conserving antibiotics for the future: New ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective

23 May 2018

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Critical shortage of new antibiotics in development against multidrug-resistant bacteria—Time to react is now

23 May 2018

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Synergy of fosfomycin with other antibiotics for Gram-positive and Gram-negative bacteria

23 May 2018

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Fosfomycin for the treatment of multidrug-resistant, including extended-spectrum beta-lactamase producing, Enterobacteriaceae infections: a systematic review.

23 May 2018

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Antimicrobial susceptibility of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Enterobacteriaceae isolates to fosfomycin

23 May 2018

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Fosfomycin: an old, new friend?

23 May 2018

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Clinical significance of the pharmacokinetic and pharmacodynamic characteristics of fosfomycin for the treatment of patients with systemic infections

23 May 2018

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Fosfomycin for the treatment of infections caused by multidrug-resistant non-fermenting Gram-negative bacilli: a systematic review of microbiological, animal and clinical studies

23 May 2018

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Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

23 May 2018

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Fosfomycin: use beyond urinary tract and gastrointestinal infections

23 May 2018

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Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE

23 May 2018

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The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America

23 May 2018

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Role of ciprofloxacin in its synergistic effect with fosfomycin on drug-resistant strains of Pseudomonas aeruginosa

23 May 2018

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Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship

23 May 2018

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Fosfomycin resistance proteins: a nexus of glutathione transferases and epoxide hydrolases in a metalloenzyme superfamily

23 May 2018

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Antibiotic abscess penetration: fosfomycin levels measured in pus and simulated concentration-time profiles

23 May 2018

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Resistance to antibiotics: are we in the post-antibiotic era?

23 May 2018

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Fosfomycin therapy for multiresistant Pseudomonas aeruginosa in cystic fibrosis

23 May 2018

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Penetration of fosfomycin into inflammatory lesions in patients with cellulitis or diabetic foot syndrome

23 May 2018

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Distribution and antimicrobial activity of fosfomycin in the interstitial fluid of human soft tissues.

23 May 2018

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Characterization of the fomA and fomB gene products from Streptomyces wedmorensis, which confer fosfomycin resistance on Escherichia coli.

23 May 2018

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Effects of fosfomycin and imipenem-cilastatin on the nephrotoxicity of vancomycin and cisplatin in rats

23 May 2018

1 reference

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Emergence of fosfomycin-resistant isolates of Shiga-like toxin-producing Escherichia coli O26

23 May 2018

1 reference

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Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men.

23 May 2018

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MurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coli

23 May 2018

1 reference

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Fosfomycin kinetics after intravenous and oral administration to human volunteers

23 May 2018

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Fosfomycin concentrations in serum and bile (author's transl)

23 May 2018

1 reference

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The mechanism of action of fosfomycin (phosphonomycin)

23 May 2018

1 reference

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Isolation and characterization of mutations affecting the transport of hexose phosphates in Escherichia coli

23 May 2018

1 reference

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Antibacterial activity of cefmetazole alone and in combination with fosfomycin against methicillin- and cephem-resistant Staphylococcus aureus

23 May 2018

1 reference

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Penetration of fosfomycin into cerebrospinal fluid across non-inflamed and inflamed meninges

23 May 2018

1 reference

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Comparative pharmacokinetics of tromethamine fosfomycin and calcium fosfomycin in young and elderly adults

23 May 2018

1 reference

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An increase in the antimicrobial activity in vitro of fosfomycin under anaerobic conditions

23 May 2018

1 reference

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Effect of non-beta-lactam antibiotics on penicillin-binding protein synthesis of Enterococcus hirae ATCC 9790.

23 May 2018

1 reference

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Mechanisms of intestinal absorption of the antibiotic, fosfomycin, in brush-border membrane vesicles in rabbits and humans.

23 May 2018

1 reference

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Fosfomycin: Laboratory Studies

23 May 2018

1 reference

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Fosfomycin: Absorption and Excretion

23 May 2018

1 reference

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Characterization of spontaneous fosfomycin (phosphonomycin)-resistant cells of Escherichia coli B in vitro

23 May 2018

1 reference

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In vitro activity of colistin or sulbactam in combination with fosfomycin or imipenem against clinical isolates of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemases.

23 May 2018

1 reference

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Fosfomycin: efficacy against infections caused by multidrug-resistant bacteria

15 August 2018

1 reference

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Synergy of fosfomycin with carbapenems, colistin, netilmicin, and tigecycline against multidrug-resistant Klebsiella pneumoniae, Escherichia coli, and Pseudomonas aeruginosa clinical isolates.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Extracellular concentrations of fosfomycin in lung tissue of septic patients

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Intravenous fosfomycin for the treatment of nosocomial infections caused by carbapenem-resistant Klebsiella pneumoniae in critically ill patients: a prospective evaluation

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

High fosfomycin concentrations in bone and peripheral soft tissue in diabetic patients presenting with bacterial foot infection.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Fosfomycin for Pseudomonas-related exacerbations of cystic fibrosis

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Antimicrobial susceptibility of multidrug-resistant Gram negative bacteria to fosfomycin.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Pharmacokinetic and pharmacodynamic aspects of antimicrobial agents for the treatment of uncomplicated urinary tract infections.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Does combination antimicrobial therapy reduce mortality in Gram-negative bacteraemia? A meta-analysis

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Protective effect of fosfomycin on gentamicin-induced lipid peroxidation of rat renal tissue

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Concentrations of fosfomycin in the cerebrospinal fluid of neurointensive care patients with ventriculostomy-associated ventriculitis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Target site penetration of fosfomycin in critically ill patients

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Effectiveness of fosfomycin combined with other antimicrobial agents against multidrug-resistant Pseudomonas aeruginosa isolates using the efficacy time index assay

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Fosfomycin monophosphate and fosfomycin diphosphate, two inactivated fosfomycin derivatives formed by gene products of fomA and fomB from a fosfomycin producing organism Streptomyces wedmorensis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Pharmacokinetic profile of fosfomycin trometamol

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

Degree of absorption, pharmacokinetics of fosfomycin trometamol and duration of urinary antibacterial activity

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5745467

In-vitro activity of antimicrobial agent combinations against multiresistant Acinetobacter baumannii

15 August 2018

1 reference

12 December 2020

Pharmacokinetics of fosfomycin

1 reference

12 December 2020

Pharmacokinetic comparison between fosfomycin and other phosphonic acid derivatives

1 reference

12 December 2020

Pharmacokinetic study of fosfomycin and its bioavailability

1 reference

12 December 2020

The influence of uremia on the accessibility of phosphomycin into interstitial tissue fluid

1 reference

12 December 2020

Antibacterial spectrum of fosfomycin trometamol

1 reference

12 December 2020

Blood and urinary concentrations of fosfomycin as a function of the renal function value

1 reference

12 December 2020

Fosfomycin trometamol: multiple-dose regimen for the treatment of lower urinary tract infections

1 reference

12 December 2020

Pharmacokinetics of Phosphonomycin in Man I:Intravenous Administration

1 reference

12 December 2020

Pharmacokinetic profile of fosfomycin trometamol (Monuril)

1 reference

12 December 2020

In vitro activity of fosfomycin combined with ceftazidime, imipenem, amikacin, and ciprofloxacin against Pseudomonas aeruginosa

1 reference

12 December 2020

Phosphonomycin, a New Antibiotic Produced by Strains of Streptomyces

1 reference

12 December 2020

Fosfomycin Monophosphate and Fosfomycin Diphosphate, Two Inactivated Fosfomycin Derivatives Formed by Gene Products of fomA and fomB from a Fosfomycin Producing Organism Streptomyces wedmorensis.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.49.502

Identifiers

DOI

10.3390/ANTIBIOTICS6040024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29088073 AND SRC:MED&resulttype=core&format=json

8 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29088073 AND SRC:MED&resulttype=core&format=json

8 April 2020

PubMed publication ID

29088073

1 reference