Kinetics and thermodynamics of ligand binding by cytochrome P450 3A4. (Q46935182)

26 December 2017

title

Kinetics and thermodynamics of ligand binding by cytochrome P450 3A4. (English)

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26 December 2017

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1

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26 December 2017

author name string

F Peter Guengerich

series ordinal

2

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26 December 2017

language of work or name

English

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publication date

8 February 2006

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26 December 2017

Journal of Biological Chemistry

number of pages

10

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based on heuristic

inferred from page(s)

published in

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26 December 2017

volume

281

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26 December 2017

issue

14

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26 December 2017

page(s)

9127-9136

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26 December 2017

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

cites work

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Structures of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Summary of information on human CYP enzymes: human P450 metabolism data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Testosterone 1 beta-hydroxylation by human cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

7,8-Benzoflavone stimulates the metabolic activation of aflatoxin B1 to mutagens by human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Binding and oxidation of alkyl 4-nitrophenyl ethers by rabbit cytochrome P450 1A2: evidence for two binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Examination of purported probes of human CYP2B6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Atypical kinetic profiles in drug metabolism reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Modelling atypical CYP3A4 kinetics: principles and pragmatism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Pyrene.pyrene complexes at the active site of cytochrome P450 3A4: evidence for a multiple substrate binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

A kinetic model for the metabolic interaction of two substrates at the active site of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Kinetic analysis for multiple substrate interaction at the active site of cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Analysis of homotropic and heterotropic cooperativity of diazepam oxidation by CYP3A4 using site-directed mutagenesis and kinetic modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

The thermodynamic landscape of testosterone binding to cytochrome P450 3A4: ligand binding and spin state equilibria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Reduction of cytochrome b5 by NADPH-cytochrome P450 reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Kinetic analysis of oxidation of coumarins by human cytochrome P450 2A6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

A survey of the year 2002 literature on applications of isothermal titration calorimetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

A survey of the year 2003 literature on applications of isothermal titration calorimetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Kinetics of Ferric Cytochrome P450 Reduction by NADPH−Cytochrome P450 Reductase: Rapid Reduction in the Absence of Substrate and Variations among Cytochrome P450 Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Temperature-dependent spin equilibrium of microsomal and solubilized cytochrome P-450 from rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Influence of P450 3A4 SRS-2 residues on cooperativity and/or regioselectivity of aflatoxin B(1) oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511375200

21 January 2018

Identifiers

DOI

10.1074/JBC.M511375200

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26 December 2017

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26 December 2017