Effects of prothrombin on the individual activated protein C-mediated cleavages of coagulation factor Va. (Q46806167)

25 December 2017

title

Effects of prothrombin on the individual activated protein C-mediated cleavages of coagulation factor Va. (English)

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25 December 2017

author name string

Sinh Tran

series ordinal

1

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25 December 2017

Eva Norstrøm

series ordinal

2

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25 December 2017

Björn Dahlbäck

series ordinal

3

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25 December 2017

language of work or name

English

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publication date

15 January 2008

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25 December 2017

Journal of Biological Chemistry

published in

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25 December 2017

volume

283

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issue

11

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25 December 2017

page(s)

6648-6655

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25 December 2017

Blood coagulation and its regulation by anticoagulant pathways: genetic pathogenesis of bleeding and thrombotic diseases

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Prothrombin kringle 1 domain interacts with factor Va during the assembly of prothrombinase complex.

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Exosites in the substrate specificity of blood coagulation reactions

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Prothrombin residues 473-487 contribute to factor Va binding in the prothrombinase complex

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A control switch for prothrombinase: characterization of a hirudin-like pentapeptide from the COOH terminus of factor Va heavy chain that regulates the rate and pathway for prothrombin activation.

21 January 2018

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Peptide Bond Cleavages and Loss of Functional Activity during Inactivation of Factor Va and Factor VaR506Q by Activated Protein C

21 January 2018

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Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C

21 January 2018

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Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C

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Mutation in blood coagulation factor V associated with resistance to activated protein C.

21 January 2018

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Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C

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Importance of protein S and phospholipid for activated protein C-mediated cleavages in factor Va.

21 January 2018

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Effects of factor Xa and protein S on the individual activated protein C-mediated cleavages of coagulation factor Va.

21 January 2018

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Inhibition of the anticoagulant activity of protein S by prothrombin

21 January 2018

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A chimeric protein C containing the prothrombin Gla domain exhibits increased anticoagulant activity and altered phospholipid specificity.

21 January 2018

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Enhanced rate of cleavage at Arg-306 and Arg-506 in coagulation factor Va by Gla domain-mutated human-activated protein C.

21 January 2018

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Small-volume extrusion apparatus for preparation of large, unilamellar vesicles

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Proposed structural models of the prothrombinase (FXa-FVa) complex

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Characterization of a factor Xa binding site on factor Va near the Arg-506 activated protein C cleavage site.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M708036200

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25 December 2017

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25 December 2017