Immunotherapy reduces vascular amyloid-beta in PDAPP mice. (Q46798116)

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9 January 2020

title

Immunotherapy reduces vascular amyloid-beta in PDAPP mice (English)

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Sally Schroeter

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Karen Khan

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Robin Barbour

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Minhtam Doan

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Ming Chen

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Terry Guido

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Davinder Gill

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Guriqbal Basi

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Dale Schenk

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Peter Seubert

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Dora Games

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language of work or name

English

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publication date

1 July 2008

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9 January 2020

published in

Journal of Neuroscience

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volume

28

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issue

27

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page(s)

6787-6793

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

9 January 2020

cites work

1 reference

12 December 2020

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

12 December 2020

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

12 December 2020

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

1 reference

12 December 2020

Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy.

1 reference

12 December 2020

Structural and functional disruption of vascular smooth muscle cells in a transgenic mouse model of amyloid angiopathy

1 reference

12 December 2020

Cerebral hemorrhage after passive anti-Abeta immunotherapy

1 reference

12 December 2020

Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology

1 reference

12 December 2020

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

1 reference

12 December 2020

Capillary and arterial cerebral amyloid angiopathy in Alzheimer's disease: defining the perivascular route for the elimination of amyloid beta from the human brain

1 reference

12 December 2020

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease

1 reference

12 December 2020

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

1 reference

12 December 2020

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease

1 reference

12 December 2020

Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.

1 reference

12 December 2020

Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.

1 reference

12 December 2020

Amyloid angiopathy-related vascular cognitive impairment.

1 reference

12 December 2020

Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage

1 reference

12 December 2020

Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease

1 reference

12 December 2020

Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.

1 reference

12 December 2020

Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease.

1 reference

12 December 2020

Vessel ultrastructure in APP23 transgenic mice after passive anti-Abeta immunotherapy and subsequent intracerebral hemorrhage

1 reference

12 December 2020

Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease

1 reference

12 December 2020

Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice.

1 reference

12 December 2020

Mice as models: transgenic approaches and Alzheimer's disease.

1 reference

12 December 2020

Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis

1 reference

12 December 2020

Abeta species removal after abeta42 immunization

1 reference

12 December 2020

Blocking the apolipoprotein E/amyloid-beta interaction as a potential therapeutic approach for Alzheimer's disease

1 reference

12 December 2020

Antibody-mediated clearance of amyloid-beta peptide from cerebral amyloid angiopathy revealed by quantitative in vivo imaging.

1 reference

12 December 2020

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

12 December 2020

Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: the CERAD experience, Part XV.

1 reference

12 December 2020

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

1 reference

12 December 2020

10.1523/JNEUROSCI.2377-07.2008

Identifiers

DOI

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9 January 2020

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9 January 2020

PubMed publication ID

18596154

1 reference